公开(公告)号：US06951411B1

公开(公告)日：2005-10-04

申请号：US10018913

申请日：2000-06-15

Applicant: Krishna S. Kumar ,  Danny F. Lincoln ,  Jonathan A. Eppstein ,  Michael R. Hatch

Inventor： Krishna S. Kumar ,  Danny F. Lincoln ,  Jonathan A. Eppstein ,  Michael R. Hatch

IPC: A61B17/00 ,  A61B18/20 ,  F21V14/06

CPC classification number: A61B18/20 ,  A61B2017/00765 ,  A61B2018/20351

Abstract: An improved light beam generation and focusing device (15, 50) has a light source (16, 51) constructed and arranged to emit at least one beam of light (20), and a lens assembly (17, 19, 56) constructed and arranged to focus the at least one beam of light on a surface plane. The device is constructed and arranged to sequentially direct the at least one beam of light to at least two spaced locations (21, 21′) on the surface plane. The lens assembly comprises a collimating lens (17), and a spaced focusing lens (19).

Abstract translation: 改进的光束产生和聚焦装置（15,50）具有构造和布置成发射至少一个光束（20）的光源（16,51），以及构成并构造的透镜组件（17,19,56） 布置成将至少一束光聚焦在表面上。 该装置被构造和布置成将至少一束光顺序地引导到表面上的至少两个间隔开的位置（21,21'）。 透镜组件包括准直透镜（17）和间隔开的聚焦透镜（19）。

公开(公告)号：US06925317B1

公开(公告)日：2005-08-02

申请号：US10018001

申请日：2000-06-12

Applicant: Mark A. Samuels ,  Krishna S. Kumar ,  Garrett T. Robinson ,  J. David Farquhar ,  Allison Minton ,  Diedre Williams ,  Michael R. Hatch ,  Alan M. Smith ,  Teresa Woods ,  Mark Vreeke

Inventor： Mark A. Samuels ,  Krishna S. Kumar ,  Garrett T. Robinson ,  J. David Farquhar ,  Allison Minton ,  Diedre Williams ,  Michael R. Hatch ,  Alan M. Smith ,  Teresa Woods ,  Mark Vreeke

IPC: A61B5/00 ,  A61B10/00 ,  A61B17/00

CPC classification number: A61B5/6833 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150343 ,  A61B5/150748 ,  A61B5/150961 ,  A61B5/150969 ,  A61B5/15111 ,  A61B5/15134 ,  A61B5/157 ,  A61B10/0045 ,  A61B2017/00477 ,  A61B2017/00482

Abstract: An alignment device and related systems and methods for aligning at least one apparatus with respect to a surface of a tissue. The alignment device comprises a tissue interface member suitable for positioning on the surface of the tissue and mating with the apparatus to maintain alignment of the apparatus during an operation of the apparatus. The alignment device is useful to align various apparatus that are part of a continuous analyte monitoring system.

Abstract translation: 对准装置以及用于相对于组织表面对准至少一个装置的相关系统和方法。 对准装置包括适于定位在组织的表面上并与装置配合的组织接口构件，以在装置的操作期间保持设备的对准。 对准装置可用于对准作为连续分析物监测系统的一部分的各种装置。

公开(公告)号：US06704587B1

公开(公告)日：2004-03-09

申请号：US09937865

申请日：2002-05-21

Applicant: Krishna S. Kumar ,  John J. Pasqua

Inventor： Krishna S. Kumar ,  John J. Pasqua

IPC: A61B500

CPC classification number: A61B5/1455 ,  A61B5/14532

Abstract: A system and method for detecting substances such as glucose in tissue. The system comprises an assay device and an optical apparatus. The assay device comprises a reactive region that is responsive to at least one substance in fluid to be collected from the tissue when the fluid is in contact with the reactive region, and which reactive region is also responsive to a first type of optical energy suitable to heat up and transfer heat by conduction to the tissue to ablate the tissue and form at least one opening in the tissue from which fluid is collected. The optical apparatus has an activation head to which the assay device is attached, and a first optical energy source that outputs a first type of optical energy. An optical detecting device is included in the optical apparatus that measures a characteristic of the at least one substance from the response of the reactive region when the reactive region is in contact with the at least one substance.

Abstract translation: 用于检测组织中诸如葡萄糖的物质的系统和方法。 该系统包括测定装置和光学装置。 测定装置包括当流体与反应性区域接触时响应于待从组织中收集的流体中的至少一种物质的反应区域，以及哪个反应性区域也对第一类型的适合于 通过传导加热和传递热量到组织以烧蚀组织并在组织中形成至少一个开口，从该组织中收集流体。 光学装置具有附着有测定装置的激活头和输出第一类型的光能的第一光能源。 光学检测装置包括在光学装置中，当反应区域与至少一种物质接触时，该反应区域的响应中测量至少一种物质的特性。