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公开(公告)号：US20070281333A1
公开(公告)日：2007-12-06
申请号：US11420881
申请日：2006-05-30
Applicant: Kuo-Chen Yeh , Cheng-Che Sage Kung
Inventor： Kuo-Chen Yeh , Cheng-Che Sage Kung
Abstract: Disclosed herein are recombinant copper or zinc binding polypeptides containing at least one copper or zinc binding motif and a sequence heterologous to it. Also disclosed is a method to reduce the concentration of a free copper or zinc ion in a substrate by contacting it with a recombinant polypeptide containing a copper or zinc binding motif. A further method relates to reducing the concentration of a free copper or zinc ion in a substrate by contacting it with a host cell that expresses a recombinant polypeptide containing a copper or zinc binding motif.
Abstract translation: 本文公开了含有至少一个铜或锌结合基序和与其异源的序列的重组铜或锌结合多肽。 还公开了通过使其与含有铜或锌结合基序的重组多肽接触来降低底物中游离铜或锌离子的浓度的方法。 另一种方法涉及通过使其与表达含有铜或锌结合基序的重组多肽的宿主细胞接触来降低底物中游离铜或锌离子的浓度。
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公开(公告)号：US06121213A
公开(公告)日：2000-09-19
申请号：US123345
申请日：1998-07-28
Applicant: Democrita E. Vergara , Michael E. Trama , Kuo-Chen Yeh
Inventor： Democrita E. Vergara , Michael E. Trama , Kuo-Chen Yeh
CPC classification number: A61K8/22 , A61Q11/02 , A61K2800/52
Abstract: A denture cream for cleaning dentures and removable dental prostheses comprising a peroxide stabilized against chemical degradation by a combination of a bicarbonate and a phosphate, such as an alkali monofluorophosphate.
Abstract translation: 一种用于清洁假牙和可拆卸牙科假体的义齿霜，其包含通过碳酸氢盐和磷酸盐的组合（例如碱金属一氟磷酸盐）的化学降解而稳定的过氧化物。
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公开(公告)号：US5225441A
公开(公告)日：1993-07-06
申请号：US63324
申请日：1987-06-18
Applicant: Richard I. Vogel , Kuo-Chen Yeh , Frank J. Sena
Inventor： Richard I. Vogel , Kuo-Chen Yeh , Frank J. Sena
IPC: A61K8/00 , A61K8/36 , A61K9/20 , A61K9/68 , A61K31/20 , A61P1/02 , A61P29/00 , A61Q11/00 , C07C57/12
CPC classification number: A61Q11/00 , A61K31/20 , A61K8/361 , Y10S514/90 , Y10S514/901 , Y10S514/902
Abstract: Omega-3, 20-22 carbon atom, hexa- or penta-unsaturated fatty acids are used in the treatment of periodontal disease.
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公开(公告)号：US4267164A
公开(公告)日：1981-05-12
申请号：US117124
申请日：1980-01-31
Applicant: Kuo-Chen Yeh , Frank Mazzella
Inventor： Kuo-Chen Yeh , Frank Mazzella
CPC classification number: A61Q11/00 , A61K8/21 , A61K8/365 , A61K9/0007 , A61K2800/222
Abstract: An effervescent tablet is produced by preparing a powdered tabletable composition containing stannous fluoride and malic acid and an alkali metal bicarbonate in a weight ratio of about 3:2 as the effervescent couple.
Abstract translation: 通过制备含有氟化亚锡和苹果酸和碱金属碳酸氢盐的重量比为约3:2的粉末状可形成组合物作为泡腾对来制备泡腾片剂。
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公开(公告)号：US07659362B2
公开(公告)日：2010-02-09
申请号：US11420881
申请日：2006-05-30
Applicant: Kuo-Chen Yeh , Cheng-Che Sage Kung
Inventor： Kuo-Chen Yeh , Cheng-Che Sage Kung
Abstract: Disclosed herein are recombinant copper or zinc binding polypeptides containing at least one copper or zinc binding motif and a sequence heterologous to it. Also disclosed is a method to reduce the concentration of a free copper or zinc ion in a substrate by contacting it with a recombinant polypeptide containing a copper or zinc binding motif. A further method relates to reducing the concentration of a free copper or zinc ion in a substrate by contacting it with a host cell that expresses a recombinant polypeptide containing a copper or zinc binding motif.
Abstract translation: 本文公开了含有至少一个铜或锌结合基序和与其异源的序列的重组铜或锌结合多肽。 还公开了通过使其与含有铜或锌结合基序的重组多肽接触来降低底物中游离铜或锌离子的浓度的方法。 另一种方法涉及通过使其与表达含有铜或锌结合基序的重组多肽的宿主细胞接触来降低底物中游离铜或锌离子的浓度。
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Patent Agency Ranking
公开(公告)号：US5885551A
公开(公告)日：1999-03-23
申请号：US904984
申请日：1997-08-01
Applicant: Alfred J. Smetana , Jon Hayes , Kuo-Chen Yeh , Laura McCulloch
Inventor： Alfred J. Smetana , Jon Hayes , Kuo-Chen Yeh , Laura McCulloch
CPC classification number: A61K8/733 , A61K6/0017 , A61Q11/00
Abstract: A method for treating dentinal hypersensitivity by administering a therapeutic amount of an alginate to a hypersensitive tooth.
Abstract translation: 一种通过将治疗量的藻酸盐施用于过敏性牙齿来治疗牙质过敏的方法。
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公开(公告)号：US5718885A
公开(公告)日：1998-02-17
申请号：US739279
申请日：1996-10-29
Applicant: James L. Gingold , Kenneth J. Markowitz , Kuo-Chen Yeh , Adonis Buelo , James K. Herms , Joseph Synodis
Inventor： James L. Gingold , Kenneth J. Markowitz , Kuo-Chen Yeh , Adonis Buelo , James K. Herms , Joseph Synodis
IPC: A61K8/00 , A61K8/19 , A61K8/20 , A61K8/22 , A61K8/25 , A61K8/26 , A61K8/28 , A61K8/36 , A61Q11/00 , A61K7/16 , A61K9/20 , A61K9/68
CPC classification number: A61Q11/00 , A61K8/19 , A61K8/22 , A61K8/25 , A61K8/26 , A61K8/28 , B82Y5/00 , A61K2800/413 , Y10S977/919
Abstract: Phosphate-free oral compositions containing cationically charged colloids are effective to treat tooth hypersensitivity.
Abstract translation: 含有阳离子电荷胶体的无磷酸盐口服组合物可有效治疗牙齿过敏。
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公开(公告)号：US5496558A
公开(公告)日：1996-03-05
申请号：US25174
申请日：1993-03-02
Applicant: Neil J. Napolitano , Kuo-Chen Yeh , Frank J. Sena , Phil J. Oths , Manuel M. Roque
Inventor： Neil J. Napolitano , Kuo-Chen Yeh , Frank J. Sena , Phil J. Oths , Manuel M. Roque
IPC: A23G4/00 , A61K8/86 , A61K9/00 , A61K9/20 , A61K9/68 , A61K31/045 , A61K31/19 , A61K31/765 , A61K47/32 , A61P1/00 , A61P1/02 , A61P43/00 , A61Q11/00 , A61F13/00
CPC classification number: A61K9/0058 , A61K8/0216 , A61K8/86 , A61K9/0056 , A61Q11/00
Abstract: A solid dosage form for relieving xerostomia symptoms comprising a lubricating polymer comprising polyethylene oxide and a sialogogue in a pharmaceutically acceptable, substantially non-cariogenic, carrier.
Abstract translation: 一种用于缓解口腔干燥症状的固体剂型，其包含在药学上可接受的，基本上不致龋齿的载体中的包含聚环氧乙烷和唾液酸反应的润滑聚合物。
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公开(公告)号：US5939048A
公开(公告)日：1999-08-17
申请号：US674797
申请日：1996-07-03
Applicant: Michael C. Alfano , Joseph D. Synodis , Alfred J. Smetana , Ronald S. Leight , Kuo-Chen Yeh
Inventor： Michael C. Alfano , Joseph D. Synodis , Alfred J. Smetana , Ronald S. Leight , Kuo-Chen Yeh
Abstract: An oral composition for treatment of hypersensitive teeth in which the salty taste of the desensitizing salt, such as a potassium or strontium salt, is masked by baking soda, sodium bicarbonate.
Abstract translation: 用于治疗过敏牙齿的口服组合物，其中脱敏盐如钾或锶盐的咸味被小苏打，碳酸氢钠掩蔽。
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公开(公告)号：US5032384A
公开(公告)日：1991-07-16
申请号：US302210
申请日：1989-01-27
Applicant: Kuo-Chen Yeh , Frank J. Sena , Michael C. Alfano
Inventor： Kuo-Chen Yeh , Frank J. Sena , Michael C. Alfano
IPC: A61K31/07 , A61K8/00 , A61K8/04 , A61K8/11 , A61K8/36 , A61K8/368 , A61K8/73 , A61K8/86 , A61K9/00 , A61K31/19 , A61K31/355 , A61K31/375 , A61P1/02 , A61P29/00 , A61P43/00 , A61Q11/00
CPC classification number: A61K31/19 , A61K31/355 , A61K31/375 , A61K9/006 , A61K9/0063 , Y10S514/90 , Y10S514/902
Abstract: Synergistic compositions comprising an antioxidant and an arylpropionic, non-steroidal anti-imflammatory drug used to treat certain diseases are disclosed. The compositions inhibit production of arachidonic acid cascade end-products which have been implicated as causes of tissue-destruction in periodontal disease. The compositions are administered in combination with a carrier, which may be a mucosal-tenacious polymer selected from the groups of semi-solid pastes, gels, ointments, liquids or films.
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