Pneumatic radial tire
    1.
    发明授权
    Pneumatic radial tire 失效
    气动子午线轮胎

    公开(公告)号:US06834698B2

    公开(公告)日:2004-12-28

    申请号:US09984893

    申请日:2001-10-31

    IPC分类号: B60C1500

    摘要: A pneumatic radial tire comprising a carcass, a belt layer, and a bead apex rubber. The carcass includes an inner carcass ply and an outer carcass ply that passes outside of the inner carcass. The bead portions are provided with a U-shaped first bead reinforcing layer and a second bead reinforcing layer. And the tire is suitable for use as a high performance tire being capable of improving initial response characteristics at the time of steering and of achieving cuts in running times.

    摘要翻译: 一种充气子午线轮胎,其包括胎体,带束层和胎圈三角橡胶。 胎体包括通过内侧胎体外侧的内部胎体帘布层和外部胎体帘布层。 胎圈部分设置有U形第一胎圈加强层和第二胎圈加强层。 并且该轮胎适合用作能够改善转向时的初始响应特性并实现运行时间的削减的高性能轮胎。

    Method of differentiation from embryo-stem cell of primate to hematogenous cell
    3.
    发明申请
    Method of differentiation from embryo-stem cell of primate to hematogenous cell 审中-公开
    从灵长类动物胚胎干细胞分化为造血细胞的方法

    公开(公告)号:US20070124826A1

    公开(公告)日:2007-05-31

    申请号:US10568502

    申请日:2004-08-24

    IPC分类号: A01K67/027 C12N5/08

    摘要: A method of differentiation from an embryonic stem cell of a primate into a hematopoietic cell, comprising maintaining an embryonic stem cell of a primate under conditions suitable for induction of differentiation into a hematopoietic cell, transplanting the resulting cell into a fetus in a uterus of a pregnant sheep, rearing the fetus, administering a cytokine specific for a primate to a born lamb, and obtaining a hematopoietic cell of a primate from a sheep obtained by rearing the lamb, a method for producing a hematopoietic cell of a primate, a hematopoietic cell obtained by the method, and a method for producing a chimeric sheep which produces a hematopoietic cell of a primate, comprising maintaining an embryonic stem cell of a primate under conditions suitable for induction of differentiation into a hematopoietic cell, and transplanting the resulting cell into a fetus in a uterus of a pregnant sheep. According to the present invention, it becomes possible to develop a means for treating a disease or a condition requiring construction of a hematopoietic system or an action of a hematopoietic cell.

    摘要翻译: 一种从灵长类动物的胚胎干细胞分化成造血细胞的方法,包括在适于诱导分化成造血细胞的条件下保持灵长类动物的胚胎干细胞,将所得细胞移植到子宫内的胎儿中 怀孕的绵羊,养育胎儿,向生长的羔羊施用特异性的灵长类动物的细胞因子,以及从通过饲养羊羔获得的绵羊获得灵长类动物的造血细胞,产生灵长类动物的造血细胞的方法,造血细胞 通过该方法获得的嵌合绵羊的制备方法以及产生灵长类动物造血细胞的嵌合羊的方法,包括在适于诱导分化成造血细胞的条件下保持灵长类动物的胚胎干细胞,并将得到的细胞移植到 胎儿在​​怀孕的绵羊的子宫。 根据本发明,可以开发用于治疗需要构建造血系统或造血细胞的作用的疾病或病症的手段。