摘要:
A method of differentiation from an embryonic stem cell of a primate into a hematopoietic cell, comprising maintaining an embryonic stem cell of a primate under conditions suitable for induction of differentiation into a hematopoietic cell, transplanting the resulting cell into a fetus in a uterus of a pregnant sheep, rearing the fetus, administering a cytokine specific for a primate to a born lamb, and obtaining a hematopoietic cell of a primate from a sheep obtained by rearing the lamb, a method for producing a hematopoietic cell of a primate, a hematopoietic cell obtained by the method, and a method for producing a chimeric sheep which produces a hematopoietic cell of a primate, comprising maintaining an embryonic stem cell of a primate under conditions suitable for induction of differentiation into a hematopoietic cell, and transplanting the resulting cell into a fetus in a uterus of a pregnant sheep. According to the present invention, it becomes possible to develop a means for treating a disease or a condition requiring construction of a hematopoietic system or an action of a hematopoietic cell.
摘要:
A pneumatic radial tire comprising a carcass, a belt layer, and a bead apex rubber. The carcass includes an inner carcass ply and an outer carcass ply that passes outside of the inner carcass. The bead portions are provided with a U-shaped first bead reinforcing layer and a second bead reinforcing layer. And the tire is suitable for use as a high performance tire being capable of improving initial response characteristics at the time of steering and of achieving cuts in running times.
摘要:
A method of manufacturing a strip of unvulcanized rubber compound including short fibers oriented towards specific directions is disclosed, and the method comprises: extruding a mixture of unvulcanized rubber and short fibers to form a strip of the mixture and to orient the short fibers towards the extruding direction; and piercing the strip with needles in a thickness direction of the strip to orient the short fibers towards the piercing direction.