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8 条记录 (耗时 0.015 秒)

    Methods, Compositions and Devices Related to Seaweed Masks
    1.
    发明申请
    Methods, Compositions and Devices Related to Seaweed Masks 有权

    公开(公告)号：US20210186826A1

    公开(公告)日：2021-06-24

    申请号：US17252241

    申请日：2019-06-25

    申请人： Laclede, Inc.

    发明人： Michael Pellico

    IPC分类号： A61K8/02 ,  A45D44/00 ,  A61K8/04 ,  A61K8/25 ,  A61K8/34 ,  A61K8/73 ,  A61K8/9717 ,  A61K8/92 ,  A61K8/9789 ,  A61Q19/00 ,  A61K8/65 ,  A61K8/67

    摘要： Methods, compositions and devices for customizing a cosmetic mask for application to an individual, the cosmetic mask comprising a gel-like formulation that, when heated, can be customized for specific application to the individual. The invention further provides for a semi-solid starting formulation comprising a solvent, a humectant, a thickener, an acid, water and an effective amount of agar, wherein the semi-solid starting formulation forms a hydrogel when heated. Specifically, the semi-solid starting formulation, once heated, is applied to the skin of an individual while still warm, then forming a gel-like material once the formulation is allowed to fully cool on the skin.

    Use of Hydrolytic and Oxidative Enzymes to Dissolve Biofilm in Airway Passages
    7.
    发明申请
    Use of Hydrolytic and Oxidative Enzymes to Dissolve Biofilm in Airway Passages 审中-公开
    使用水解和氧化酶将生物膜溶解在气道通道中

    公开(公告)号：US20160144004A1

    公开(公告)日：2016-05-26

    申请号：US14991571

    申请日：2016-01-08

    申请人： Laclede, Inc.

    发明人： Michael Pellico

    IPC分类号： A61K38/54 ,  A61K38/40 ,  A61K31/573 ,  A61K38/44 ,  A61K38/47 ,  A61K38/46 ,  A61K45/06

    CPC分类号： A61K38/54 ,  A61K31/573 ,  A61K38/40 ,  A61K38/44 ,  A61K38/443 ,  A61K38/465 ,  A61K38/47 ,  A61K45/06 ,  C12Y111/01007 ,  C12Y302/01 ,  C12Y302/01011 ,  C12Y302/01015 ,  C12Y302/01017 ,  A61K2300/00

    摘要： A composition for removal of biofilm in the airway passage is useful for the treatment of infections such as pneumonia cause by Mycoplasma pneumoniae. In general, the composition comprises: (1) a quantity of at least one enzyme that catalyzes the hydrolysis of a bond that connects two monosaccharides in a polysaccharide or that connects a monosaccharide with a protein molecule in a glycoprotein sufficient to break down biofilm in the airway; and (2) a pharmaceutically acceptable carrier suitable for administration into the airway. The composition can further include ingredients such as a steroid, lysozyme, lactoferrin, or a peroxidase; if a peroxidase is included, the composition can further include an oxidase to generate peroxide as well as a substrate for the oxidase. The composition can be used in methods for treatment of an infection based on the ability of the composition to dissolve biofilm in the airway.

    摘要翻译： 用于在气道通道中去除生物膜的组合物可用于治疗由肺炎支原体引起的肺炎等感染。 通常，组合物包含：（1）一定量的至少一种酶，其催化连接多糖中的两个单糖的键的水解，或者连接单糖与蛋白质分子在足以分解生物膜中的蛋白质分子 气道 和（2）适于施用于气道的药学上可接受的载体。 该组合物还可以包括成分如类固醇，溶菌酶，乳铁蛋白或过氧化物酶; 如果包括过氧化物酶，组合物还可以包括氧化酶以产生过氧化物以及用于氧化酶的底物。 该组合物可用于基于组合物在气道中溶解生物膜的能力来治疗感染的方法。