Inertia valves
    4.
    发明授权
    Inertia valves 失效
    惯性阀

    公开(公告)号:US4735462A

    公开(公告)日:1988-04-05

    申请号:US930247

    申请日:1986-11-13

    CPC分类号: B60T8/282 F16K17/366

    摘要: An inertia valve includes a valve member which is free to move axially in a cylindrical bore and a valve seat which may be closed by the valve member is provided at one end of the cylindrical bore, said valve seat being supported on a support member so that it surrounds a port defined by the support member, the seat being spaced from the support member at its inner periphery so that it provides a flexible inner peripheral portion which may be deformed by the valve member.

    摘要翻译: 惯性阀包括可在圆柱形孔中自由移动的阀构件,并且可由阀构件封闭的阀座设置在圆柱孔的一端处,所述阀座支撑在支撑构件上,使得 它围绕由支撑构件限定的端口,座在其内周与支撑构件间隔开,使得其提供可被阀构件变形的柔性内周部分。

    Compounds and methods for inhibiting selectin-mediated function
    5.
    发明授权
    Compounds and methods for inhibiting selectin-mediated function 有权
    抑制选择蛋白介导功能的化合物和方法

    公开(公告)号:US08530448B2

    公开(公告)日:2013-09-10

    申请号:US12753452

    申请日:2010-04-02

    IPC分类号: A61K31/70 C07H15/00

    CPC分类号: C07H15/252

    摘要: Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids, which include a portion or analogue thereof) linked to a carbohydrate or glycomimetic.

    摘要翻译: 提供化合物和方法用于调节由选择素结合介导的体外和体内过程。 更具体地,描述了选择素调节剂及其用途,其中调节(例如,抑制或增强)选择素介导的功能的选择素调节剂包含称为BASAs的一类化合物(苄基氨基磺酸,其包括其部分或类似物) 与碳水化合物或糖模拟物连接。

    Compounds and methods for inhibiting selectin-mediated function
    7.
    发明授权
    Compounds and methods for inhibiting selectin-mediated function 有权
    抑制选择蛋白介导功能的化合物和方法

    公开(公告)号:US07741312B2

    公开(公告)日:2010-06-22

    申请号:US11411266

    申请日:2006-04-26

    IPC分类号: A61K31/70 C07H15/00

    CPC分类号: C07H15/252

    摘要: Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids, which include a portion or analogue thereof linked to a carbohydrate or glycomimetic.

    摘要翻译: 提供化合物和方法用于调节由选择素结合介导的体外和体内过程。 更具体地,描述了选择素调节剂及其用途,其中调节(例如,抑制或增强)选择素介导的功能的选择素调节剂包含称为BASAs的一类化合物(苄基氨基磺酸,其包括其部分或类似物连接 到糖或糖模拟物。