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1.发明授权Medical diagnostic ultrasound contrast agent destruction with reduced biological effect 失效医学诊断超声造影剂破坏，生物效应降低公开(公告)号：US07946988B2
公开(公告)日：2011-05-24
申请号：US11302567
申请日：2005-12-13
申请人： Anming He Cai , Lewis J. Thomas
发明人： Anming He Cai , Lewis J. Thomas
IPC分类号： A61B8/00
摘要： Contrast agent destruction transmissions have reduced biological effect in medical diagnostic ultrasound. Ramping-up amplitude and/or ramping-down frequency reduce biological effect. The amplitude ramps up linearly or non-linearly. The change in amplitude or frequency occurs over a single waveform or over a sequence of separate transmissions. An envelope of the single waveform or the sequence of separate transmissions has a non-uniform, asymmetrical, symmetrical, rectangular or other shape. For example, the frequency ramp-down is provided with a non-Gaussian envelope. The amplitude ramp-up or frequency ramp-down is a progressively increasing destructive characteristic or ability, destroying contrast agent at different regions relative to focal regions with a minimum of acoustic energy.
摘要翻译： 对比剂破坏传播在医学诊断超声中具有降低的生物学效应。 上升幅度和/或下降频率降低生物效应。 幅度线性或非线性地上升。 振幅或频率的变化发生在单个波形或单独传输序列上。 单个波形的包络或单独传输的序列具有不均匀，不对称，对称，矩形或其他形状。 例如，频率斜降具有非高斯包络。 幅度上升或频率斜降是逐渐增加的破坏性特征或能力，破坏相对于具有最小声能的焦点区域的不同区域处的造影剂。
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公开(公告)号：US07221972B2
公开(公告)日：2007-05-22
申请号：US10892921
申请日：2004-07-16
CPC分类号： A61B8/00 , G01S7/52098
摘要： The embodiments described herein relate to stepping through the stages of a protocol using an input device and a protocol controller for a medical diagnostic imaging system. The protocol controller may be operative to transition from one stage to a next stage in the protocol in response to no more than a single input from the input device. Thus, a single input from the input device may indicate to the protocol controller to transition to each of the stages of the protocol. In one embodiment, the same single input, such as a stage transition input, is received to transition to each stage of the at least two sequential stages. In another embodiment, different single input, such as different keys on a keyboard, may be used to transition to different stages of the at least two sequential stages. Other embodiments are provided, and each of the embodiments described herein can be used alone or in combination with one another.
摘要翻译： 本文描述的实施例涉及使用输入设备和用于医学诊断成像系统的协议控制器来逐步执行协议的阶段。 协议控制器可以响应于不超过来自输入设备的单个输入而在协议中从一个级转换到下一级。 因此，来自输入设备的单个输入可以向协议控制器指示转换到协议的每个阶段。 在一个实施例中，接收相同的单个输入，例如级转换输入，以转换到至少两个顺序级的每个级。 在另一个实施例中，可以使用不同的单个输入，例如键盘上的不同的键来转换到至少两个顺序级的不同阶段。 提供了其它实施例，并且本文所述的每个实施例可以单独使用或彼此组合使用。
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3.发明授权Medical diagnostic ultrasound system and method for contrast agent image beamformation 有权医学诊断超声系统和造影剂图像波束形成方法公开(公告)号：US06491633B1
公开(公告)日：2002-12-10
申请号：US09523075
申请日：2000-03-10
申请人： Sriram Krishnan , Lewis J. Thomas
发明人： Sriram Krishnan , Lewis J. Thomas
IPC分类号： A61B800
摘要： A method and system for contrast agent image beamformation is provided. The acoustic energy of transmit beams is spread laterally to reduce contrast agent destruction. For example, a smaller aperture is provided for contrast agent imaging than for a default imaging mode. As another example, an apodization profile with a low amplitude for edge elements for contrast agent imaging is used as compared to the edge elements for a default imaging mode. As yet another example, the focal point used for contrast agent imaging is set to be outside of the region of interest (e.g. a shallow or deep focal point).
摘要翻译： 提供了造影剂图像波束形成的方法和系统。 发射光束的声能横向扩展，以减少造影剂的破坏。 例如，与默认成像模式相比，为造影剂成像提供较小的孔径。 作为另一示例，与用于默认成像模式的边缘元素相比，使用具有用于造影剂成像的边缘元素的具有低幅度的变迹曲线。 作为另一示例，用于造影剂成像的焦点被设置为在感兴趣区域（例如，浅或深焦点）之外。
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公开(公告)号：US06309356B1
公开(公告)日：2001-10-30
申请号：US09518972
申请日：2000-03-06
IPC分类号： A61B800
CPC分类号： G01S15/8959 , G01S7/52026 , G01S7/52049 , G01S15/8909
摘要： A pulse echo beamforming system generates high spatial bandwidth ultrasound images using only a few transmit/receive events per frame. Each transmit/receive event consists of firing an unfocused or weakly focused wave and receiving and storing the echo on every receive channel. Each set of stored echoes is delayed and apodized to form component beams for each desired image point in the region insonified by that particular wave. The final images are synthesized by adding two or more of the component beams for each image point.
摘要翻译： 脉冲回波波束成形系统使用每帧仅使用少量发射/接收事件来生成高空间带宽超声图像。 每个发射/接收事件包括触发未聚焦或弱聚焦的波，并在每个接收通道上接收和存储回波。 每组存储的回波被延迟和变迹以形成由该特定波加密的区域中的每个期望图像点的分量波束。 通过为每个图像点添加两个或更多个分量光束来合成最终图像。
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5.发明授权
公开(公告)号：US5327894A
公开(公告)日：1994-07-12
申请号：US24009
申请日：1993-03-01
申请人： Lewis J. Thomas
发明人： Lewis J. Thomas
CPC分类号： G01S7/52071 , G01S15/8981
摘要： An ultrasonic imaging system includes a receiver which demodulates the echo signals received by a transducer array and dynamically focuses the baseband echo signals, and a color flow processor which includes an adaptive wall filter in the form of a circular convolution filter that enables a narrow band of wall signals to be removed without loss of data samples. The mean frequency of the resulting filtered baseband echo signals is used to indicate the velocity of flowing reflectors and to control color of the displayed image.
摘要翻译： 超声波成像系统包括：解调由换能器阵列接收的回波信号并动态聚焦基带回波信号的接收机，以及包括循环卷积滤波器形式的自适应壁滤波器的色流处理器， 墙信号被删除而不丢失数据样本。 所得到的滤波的基带回波信号的平均频率用于指示流动的反射器的速度并控制显示的图像的颜色。
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公开(公告)号：US4825117A
公开(公告)日：1989-04-25
申请号：US126138
申请日：1987-11-27
IPC分类号： B06B1/06 , B29C70/54 , G10K11/00 , H01L41/053 , H01L41/08
CPC分类号： B06B1/067 , B29C70/54 , G10K11/004 , H01L41/053
摘要： An apparatus for monitoring the curing of a fiber reinforced composite plastic which is cured at temperatures of the order of 350.degree. C. and an ultrasonic transducer assembly useful in the apparatus. The transducer assembly comprises a lithium niobate piezoelectric element having anisotropic coefficients of thermal expansion which is mounted on a metal base of the transducer assembly by means of a layer of structured copper. The structured copper is thermo-compression diffusion bonded to the lithium niobate element and to the metal base, and is compliant in a transverse direction to compensate for differential thermal expansions while affording good electrical and thermal conductivity and good acoustic coupling between the lithium niobate element and metal base.
摘要翻译： 一种用于监测在350℃温度下固化的纤维增强复合塑料的固化的装置和在该装置中有用的超声换能器组件。 换能器组件包括具有各向异性热膨胀系数的铌酸锂压电元件，其通过结构化铜层安装在换能器组件的金属基座上。 结构化铜是热压缩扩散结合到铌酸锂元素和金属基底上，并且在横向方向上是柔性的，以补偿不同的热膨胀，同时提供良好的导电性和导热性，以及铌酸锂元素与铌酸锂元素之间良好的声耦合 金属底座。
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公开(公告)号：US07311667B2
公开(公告)日：2007-12-25
申请号：US10238523
申请日：2002-09-09
申请人： Anming He Cai , Lewis J. Thomas
发明人： Anming He Cai , Lewis J. Thomas
IPC分类号： A61B8/00
CPC分类号： B06B1/0629
摘要： Transducer with different array configurations and methods of using the transducers are provided. An electrode layer on one side of a transducer device defines a one-dimensional array of elements. An electrode layer on an opposite side of the transducer device defines a multi-dimensional array. For example, one transducer device may be used for both two-dimensional imaging and three-dimensional imaging in response to the one-dimensional array and multi-dimensional array electrode configurations. Real time three-dimensional imaging and two-dimensional imaging may be provided with a single transducer. As another example, elements defined by one electrode configuration have a different surface area than elements defined by another electrode configuration. The different configurations on opposite sides of the transducer devices may be a same type (e.g. both one-dimensional arrays) or different types.
摘要翻译： 提供具有不同阵列配置的传感器和使用换能器的方法。 在换能器装置的一侧上的电极层限定了一维的元件阵列。 在换能器装置的相对侧上的电极层限定多维阵列。 例如，响应于一维阵列和多维阵列电极配置，一个换能器装置可用于二维成像和三维成像。 可以提供实时三维成像和二维成像单个换能器。 作为另一示例，由一个电极配置限定的元件具有与由另一电极配置限定的元件不同的表面积。 换能器装置的相对侧上的不同配置可以是相同类型（例如，一维阵列）或不同类型。
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公开(公告)号：US5457863A
公开(公告)日：1995-10-17
申请号：US34992
申请日：1993-03-22
CPC分类号： B06B1/0622 , A61B8/4483 , A61B8/4494 , Y10T29/42
摘要： An improved two-dimensional ultrasonic transducer array is provided by forming a plurality of elongated transducer strips each including a central body of piezoelectric material having mounted thereon a conducting inner matching layer and outer matching layer, a conducting inner backing layer and a nonconducting lossy outer backing layer, depositing a conducting film on the outer surface and one side surface of the outer matching layer and into electrical contact with the conducting backing layer of each strip and depositing a plurality of conducting films in space relation to one another on the back surface and one side surface of the lossy backing layer and into electrical contact with the conducting backing layer to provide an electric circuit to the front and back faces of the piezoelectric layer. The strips are then assembled in spaced parallel relation with insulating strips bonded therebetween, and grooves are cut transversely of the transducer strip through the matching layers, the piezoelectric layer, the inner backing layer and into but not through the lossy backing layer to thereby provide an array of individual transducers arranged in spaced parallel rows with conducting films extending from the face and back surfaces of each transducer to provide an independent electrical circuit to each transducer in the array.
摘要翻译： 通过形成多个细长的换能器带来提供改进的二维超声波换能器阵列，每个细长的换能器条包括压电材料的中心体，其上安装有导电内部匹配层和外部匹配层，导电内部背衬层和不导电有损耗的外部背衬 在外部匹配层的外表面和一个侧表面上沉积导电膜并与每个条的导电背衬层电接触并且在背面上彼此空间上沉积多个导电膜，一个 并且与导电背衬层电接触以提供到压电层的前表面和后表面的电路。 然后将条带以与之间的绝缘条隔开平行的关系组装，并且通过匹配层，压电层，内衬层横向切割槽，并且通过有损背衬层而不通过有损背衬层， 阵列的各个换能器以间隔开的平行排布置，导电膜从每个换能器的表面和后表面延伸，为阵列中的每个换能器提供独立的电路。
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9.发明授权Method and apparatus for applying synthetic aperture focusing techniques to a catheter based system for high frequency ultrasound imaging of small vessels 失效将合成孔径聚焦技术应用于基于导管的系统用于小血管的高频超声成像的方法和装置
公开(公告)号：US5186177A
公开(公告)日：1993-02-16
申请号：US803242
申请日：1991-12-05
CPC分类号： G01S15/892 , A61B8/12 , G01S15/8927 , G01S15/8956 , G01S15/8997 , G01S7/52047 , A61B8/445
摘要： A catheter based ultrasound imaging system is disclosed which is capable of providing images of coronary vessels at frequencies near 50 MHz. The catheter based system implements a Synthetic Aperture Focusing Technique (SAFT) by scanning through a miniature ultrasound transducer array to sequentially select and fully multiplex a subset of array elements to operate as a sub-aperture of the total synthetic aperture on each firing; thus reducing the number of required catheter interconnections. Each synthetic aperture array is dynamically and retrospectively focused to accommodate precision imaging at high frequency without conventional signal to noise losses.
摘要翻译： 公开了一种基于导管的超声成像系统，其能够在50MHz附近提供冠状血管的图像。 基于导管的系统通过扫描微型超声换能器阵列来实现合成孔径聚焦技术（SAFT），以顺序选择并完全复用阵列元件的子集，以在每次烧制时作为总合成孔径的子孔径进行操作; 从而减少所需导管互连的数量。 每个合成孔径阵列是动态和回顾性的聚焦，以适应高频下的精密成像，而没有常规的信噪比损失。
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10.发明授权
公开(公告)号：US4921415A
公开(公告)日：1990-05-01
申请号：US272358
申请日：1988-11-15
IPC分类号： B06B1/06 , B29C70/54 , G10K11/00 , H01L41/053
CPC分类号： B06B1/067 , B29C70/54 , G01N29/2475 , G10K11/004 , H01L41/053 , G01N2291/0251 , G01N2291/0421 , G01N2291/0422
摘要： An apparatus for monitoring the curing of a fiber reinforced composite plastic which is cured at temperatures of the order of 350.degree. C. and an ultrasonic transducer assembly useful in the apparatus. The transducer assembly comprises a lithium niobate piezoelectric element having anisotropic coefficients of thermal expansion which is mounted on a metal base of the transducer assembly by means of a layer of structured copper. The structured copper is thermo-compression diffusion bonded to the lithium niobate element and to the metal base, and is compliant in a transverse direction to compensate for differential thermal expansions while affording good electrical and thermal conductivity and good acoustic coupling between the lithium niobate element and metal base.
摘要翻译： 一种用于监测在350℃温度下固化的纤维增强复合塑料的固化的装置和在该装置中有用的超声换能器组件。 换能器组件包括具有各向异性热膨胀系数的铌酸锂压电元件，其通过结构化铜层安装在换能器组件的金属基座上。 结构化铜是热压缩扩散结合到铌酸锂元素和金属基底上，并且在横向方向上是柔性的，以补偿不同的热膨胀，同时提供良好的导电性和导热性，以及铌酸锂元素与铌酸锂元素之间良好的声耦合 金属底座。
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