公开(公告)号：US08484721B2

公开(公告)日：2013-07-09

申请号：US12534699

申请日：2009-08-03

申请人： Monica Sin-Ling Lam ,  Constantine P. Sapuntzakis

发明人： Monica Sin-Ling Lam ,  Constantine P. Sapuntzakis

IPC分类号： H04L9/32 ,  G06F12/00

CPC分类号： G06F21/53 ,  G06F2221/2149

摘要： Some embodiments of the present invention provide a system that presents an alternate computing environment on a host computing device. During operation, this system detects the presence of a removable storage device which is in communication with an interface of the host computing device. The system also locates code which implements the alternate computing environment on the removable storage device. Finally, the system runs the code which presents the alternate computing environment through an environment player on the host device, wherein the environment player prevents a user of the alternate computing environment from interacting directly with a native computing environment of the host computing device.

摘要翻译： 本发明的一些实施例提供一种在主机计算设备上呈现备用计算环境的系统。 在操作期间，该系统检测与主计算设备的接口通信的可移动存储设备的存在。 该系统还可以在可移动存储设备上定位实现备用计算环境的代码。 最后，系统运行通过主机设备上的环境播放器呈现替代计算环境的代码，其中环境播放器防止替代计算环境的用户直接与主计算设备的本机计算环境进行交互。

公开(公告)号：US08266576B2

公开(公告)日：2012-09-11

申请号：US11833208

申请日：2007-08-02

申请人： Monica Sin-Ling Lam ,  Andrew D. Berkheimer ,  Constantine P. Sapuntzakis ,  John C. Whaley ,  Ramesh U. V. Chandra ,  Michael K. Chen ,  Won-Suk Chun ,  Kelvin Kam-Suen Yue

发明人： Monica Sin-Ling Lam ,  Andrew D. Berkheimer ,  Constantine P. Sapuntzakis ,  John C. Whaley ,  Ramesh U. V. Chandra ,  Michael K. Chen ,  Won-Suk Chun ,  Kelvin Kam-Suen Yue

IPC分类号： G06F9/44

CPC分类号： G06F8/63 ,  G06F8/658 ,  G06F9/44505 ,  G06F9/45533 ,  G06F17/30233

摘要： Methods, systems, and apparatus, including computer program apparatus, implementing techniques for publishing, subscribing to, or playing live appliances. A live appliance includes a current virtual machine image. In publishing, a proxy file of a live appliance file type is provided to the publisher. The type is mapped to a live appliance player; so that when a proxy file is opened, the current virtual machine image is run. The player automatically binds a writeable file system external to the virtual machine image to the image to provide file storage that is accessible from within the virtual machine image and from a host operating system. The player also creates a subscription to the live appliance on the host computer if one does not exist when the proxy file is run. With the subscription, the player runs the then-current virtual machine image whenever the live appliance is run.

摘要翻译： 方法，系统和装置，包括计算机程序装置，用于发布，订阅或播放活
动电器的技术。 活动设备包括当前的虚拟机映像。 在发布时，会向发布商提供活动家电文件类型的代理文件。 该类型映射到活动家电播放器; 以便当代理文件打开时，将运行当前的虚拟机映像。 播放器自动将虚拟机映像外部的可写文件系统绑定到映像，以提供可从虚拟机映像和主机操作系统访问的文件存储。 如果代理文件运行时，播放器还会在主机上创建对主机的订阅。 通过订阅，播放器将在运行live设备时运行当前的虚拟机映像。

公开(公告)号：US07890689B2

公开(公告)日：2011-02-15

申请号：US12043672

申请日：2008-03-06

申请人： Monica Sin-Ling Lam ,  Constantine Paul Sapuntzakis ,  Ramesh U. V. Chandra ,  Nickolai Borisovich Zeldovich ,  Mendel Rosenblum ,  James Eugene Chow ,  David James Brumley

发明人： Monica Sin-Ling Lam ,  Constantine Paul Sapuntzakis ,  Ramesh U. V. Chandra ,  Nickolai Borisovich Zeldovich ,  Mendel Rosenblum ,  James Eugene Chow ,  David James Brumley

IPC分类号： G06F12/00

CPC分类号： G06F9/44505 ,  G06F11/1456 ,  G06F11/1464 ,  H04L67/34 ,  H04L69/329

摘要： Various approaches for virtual appliance management are described. In one approach a virtual appliance repository stores one or more virtual appliances and is coupled to the host computer via a network. A storage device stores a transceiver program capable when executed on said host computer of requesting and receiving the virtual appliances, and generating for each received virtual appliance a respective local copy on the host computer of each received virtual appliance. The local copy is private to the host computer. The transceiver program further binds the virtual appliances to the host computer and obtains user data relevant to the virtual appliances. The transceiver program runs each of the virtual appliances from the respective private local copies on the host computer.

摘要翻译： 描述了虚拟设备管理的各种方法。 在一种方法中，虚拟设备存储库存储一个或多个虚拟设备，并且经由网络耦合到主计算机。 存储设备存储在所述主机计算机上执行请求和接收虚拟设备时能够收发的收发器程序，并且为每个接收的虚拟设备生成每个接收到的虚拟设备的主计算机上的相应本地副本。 本地副本对主机是私有的。 收发器程序还将虚拟设备绑定到主计算机，并获得与虚拟设备相关的用户数据。 收发器程序从主机上的相应私有本地副本运行每个虚拟设备。

公开(公告)号：US07645616B2

公开(公告)日：2010-01-12

申请号：US11875271

申请日：2007-10-19

申请人： Aimin Xu ,  Yu Wang ,  Karen Siu Ling Lam

发明人： Aimin Xu ,  Yu Wang ,  Karen Siu Ling Lam

IPC分类号： G01N33/53

CPC分类号： C12Q1/6883 ,  A61K31/44 ,  A61K31/4439 ,  C07K14/47 ,  C12Q2600/136 ,  C12Q2600/158 ,  Y10S436/811

摘要： Methods and compositions for identifying and treating obesity and obesity-induced metabolic disorders are provided. One aspect provides a method for the evaluation of risk and progression of glucose tolerance, insulin resistance and Type 2 diabetes in mammalian subjects. The method includes measuring the concentration of circulating lipocalin-2 in a subject and comparing the measured level to lipocalin-2 to a reference level. Another aspect provides methods of treating insulin resistance, type 2 diabetes and other related complications by administering to a patient a composition that can reduce the circulating levels of lipocalin-2, for example a lipocalin-2 antagonist.

摘要翻译： 提供了用于鉴定和治疗肥胖和肥胖诱导的代谢紊乱的方法和组合物。 一方面提供了用于评估哺乳动物受试者中葡萄糖耐量，胰岛素抵抗和2型糖尿病的风险和进展的方法。 该方法包括测量受试者中循环脂质运载蛋白-2的浓度，并将测量的水平与脂笼蛋白-2比较至参考水平。 另一方面提供了通过向患者施用可以降低脂质运载蛋白-2（例如脂质运载蛋白-2拮抗剂）的循环水平的组合物来治疗胰岛素抵抗，2型糖尿病和其它相关并发症的方法。

公开(公告)号：US07548957B1

公开(公告)日：2009-06-16

申请号：US10141583

申请日：2002-05-07

申请人： Derek Wichmann ,  Ling Lam

发明人： Derek Wichmann ,  Ling Lam

IPC分类号： G06F15/16

CPC分类号： G06F17/30893 ,  Y10S707/99934

摘要： A method and mechanism for portal web site architecture supporting a plurality of portlets, which are configurable content area displayable on a web page that provides content or performs one or more associated functions or both. Web providers provide the functionality and house the content for portlets. In response to receiving a request for a web page with a portlet, an application server contacts a web provider to obtain the content for the portlet, and assembles the web page using the retrieved content from the web provider and information stored in a database about the structure, appearance, and operation of the web page. Discussion forum portlets, notice board portlets, and memo pad portlets may be used to provide discussion forum functionality, notice board functionality, and memo pad functionality respectively.

摘要翻译： 支持多个portlet的门户网站架构的方法和机制，其是可提供内容或执行一个或多个相关功能或两者的网页上可显示的可配置内容区域。 Web提供商提供portlet的功能和内容。 响应于接收到具有Portlet的网页的请求，应用服务器联系web提供商以获取Portlet的内容，并使用来自web提供者的检索到的内容和存储在数据库中的信息来组装网页 网页的结构，外观和操作。 讨论论坛portlet，注意事项portlet和备忘录portlet可能分别用于提供论坛功能，注意事项功能和备忘录功能。

公开(公告)号：US20080215796A1

公开(公告)日：2008-09-04

申请号：US12043672

申请日：2008-03-06

申请人： Monica Sin-Ling Lam ,  Constantine Paul Sapuntzakis ,  Ramesh U.V. Chandra ,  Nickolai Borisovich Zeldovich ,  Mendel Rosenblum ,  James Eugene Chow ,  David James Brumley

发明人： Monica Sin-Ling Lam ,  Constantine Paul Sapuntzakis ,  Ramesh U.V. Chandra ,  Nickolai Borisovich Zeldovich ,  Mendel Rosenblum ,  James Eugene Chow ,  David James Brumley

IPC分类号： G06F12/00

CPC分类号： G06F9/44505 ,  G06F11/1456 ,  G06F11/1464 ,  H04L67/34 ,  H04L69/329

摘要： Various approaches for virtual appliance management are described. In one approach a virtual appliance repository stores one or more virtual appliances and is coupled to the host computer via a network. A storage device stores a transceiver program capable when executed on said host computer of requesting and receiving the virtual appliances, and generating for each received virtual appliance a respective local copy on the host computer of each received virtual appliance. The local copy is private to the host computer. The transceiver program further binds the virtual appliances to the host computer and obtains user data relevant to the virtual appliances. The transceiver program runs each of the virtual appliances from the respective private local copies on the host computer.

摘要翻译： 描述了虚拟设备管理的各种方法。 在一种方法中，虚拟设备存储库存储一个或多个虚拟设备，并且经由网络耦合到主计算机。 存储设备存储在所述主计算机上执行请求和接收虚拟设备时能够收发的收发器程序，并且为每个接收到的虚拟设备生成每个接收到的虚拟设备的主计算机上的相应本地副本。 本地副本对主机是私有的。 收发器程序还将虚拟设备绑定到主计算机，并获得与虚拟设备相关的用户数据。 收发器程序从主机上的相应私有本地副本运行每个虚拟设备。

公开(公告)号：US07373451B2

公开(公告)日：2008-05-13

申请号：US11007911

申请日：2004-12-08

申请人： Monica Sin-Ling Lam ,  Constantine Paul Sapuntzakis ,  Ramesh U. V. Chandra ,  Nickolai Borisovich Zeldovich ,  Mendel Rosenblum ,  James Eugene Chow ,  David James Brumley

发明人： Monica Sin-Ling Lam ,  Constantine Paul Sapuntzakis ,  Ramesh U. V. Chandra ,  Nickolai Borisovich Zeldovich ,  Mendel Rosenblum ,  James Eugene Chow ,  David James Brumley

IPC分类号： G06F12/00

CPC分类号： G06F9/44505 ,  G06F11/1456 ,  G06F11/1464 ,  H04L67/34 ,  H04L69/329

摘要： A cache-based system management architecture named “the Collective” automates system management and supports mobile computing. The Collective manages systems by manipulating virtual appliances, each encapsulating a system state. A virtual appliance (VA) may comprise a virtual network of VAs. Distributed repositories separately storing the VAs and user data. Publishers create and maintain VAs. A user plugs a bootable portable storage device implementing a VA transceiver (VAT) into a host computer. The VAT, comprising a Manager, a Cache Client, and a virtual machine monitor (VMM), authenticates the user, retrieves a copy of the latest version of a subscribed VA from the appropriate network repository, obtains user data, and automatically backs up the user data over the network in the background while running the subscribed VA. Multiple VAs can be run at the same time. With the novel caching protocol and cache charging process, the Collective performs well and has numerous advantages.

摘要翻译： 名为“集体”的基于缓存的系统管理架构自动化系统管理并支持移动计算。 集体通过操纵虚拟设备来管理系统，每个虚拟设备都封装系统状态。 虚拟设备（VA）可以包括虚拟网络的VAs。 分布式存储库分别存储VAs和用户数据。 发布商创建和维护VAs。 用户将实现VA收发器（VAT）的可引导便携式存储设备插入主计算机。 增值税，包括经理，缓存客户端和虚拟机监视器（VMM），对用户进行身份验证，从适当的网络存储库检索订阅的VA的最新版本的副本，获取用户数据，并自动备份 在运行订阅的VA时，在后台的网络上的用户数据。 多个VAs可以同时运行。 凭借新颖的高速缓存协议和缓存计费流程，集体效能良好，拥有众多优势。

公开(公告)号：US20080005121A1

公开(公告)日：2008-01-03

申请号：US11428008

申请日：2006-06-30

申请人： Monica Sin-Ling Lam ,  Kelvin Yue ,  Ramesh Chandra ,  Constantine P. Sapuntzakis ,  John Whaley ,  Guy Messalem

发明人： Monica Sin-Ling Lam ,  Kelvin Yue ,  Ramesh Chandra ,  Constantine P. Sapuntzakis ,  John Whaley ,  Guy Messalem

IPC分类号： G06F17/30

CPC分类号： G06F17/30067

摘要： Methods and apparatus, including computer program products, for network-extended storage. A portable storage device is coupled to a host computer, and network extension code stored on the portable storage device is invoked. The network extension code is operable to detect a file system write function call generated by an application executing on the host computer, the file system write function call operable to cause data to be written to the portable storage device, and cause the data to be written to the portable storage device based upon the file system write function call. The network extension code is further operable to generate a transmit determination indicative of whether to transmit the data to a network repository, and transmit the data to the network repository based upon the transmit determination.

摘要翻译： 方法和设备，包括计算机程序产品，用于网络扩展存储。 便携式存储设备耦合到主计算机，并且调用存储在便携式存储设备上的网络扩展代码。 网络扩展代码可操作以检测由在主计算机上执行的应用程序生成的文件系统写入功能调用，文件系统写入功能调用可操作以使得数据被写入便携式存储设备，并且使数据被写入 基于文件系统写入功能调用到便携式存储设备。 网络扩展码进一步可操作以产生指示是否将数据发送到网络存储库的发送确定，并且基于发送确定将数据发送到网络存储库。

公开(公告)号：US07277924B1

公开(公告)日：2007-10-02

申请号：US10141485

申请日：2002-05-07

申请人： Derek Wichmann ,  Ling Lam ,  Chieng Guo ,  Michael Winton

发明人： Derek Wichmann ,  Ling Lam ,  Chieng Guo ,  Michael Winton

IPC分类号： G06F15/16

CPC分类号： G06F17/30864 ,  Y10S707/99934

摘要： A method and mechanism for servicing a request for a web page from a user over a worldwide computer network using a portal management system. A user transmits a request for a web page with one or more portlets to a portal web server. The portal web server communicates with one or more web providers to obtain content for any portlets on the web page. Each web provider may communicate with one or more content retrievers, or access pre-rendered web pages generated by a performance engine, to retrieve content necessary to render the web page. Each content retriever may communicate with a content provider to obtain content. The portal web server assembles the requested web page using stored information and the appearance and operation of the web page and content supplied by the web provider.

摘要翻译： 一种用于使用门户管理系统通过全球计算机网络从用户处理对网页的请求的方法和机制。 用户向具有一个或多个Portlet的网页发送对门户web服务器的请求。 门户网站服务器与一个或多个Web提供商进行通信，以获取网页上任何portlet的内容。 每个网络提供商可以与一个或多个内容检索器进行通信，或访问由演奏引擎生成的预先呈现的网页，以检索呈现网页所需的内容。 每个内容检索者可以与内容提供商通信以获得内容。 门户网站服务器使用存储的信息以及网页提供商提供的网页和内容的外观和操作来组装所请求的网页。

公开(公告)号：US4303792A

公开(公告)日：1981-12-01

申请号：US42187

申请日：1979-05-24

申请人： Hsaio-Ling Lam

发明人： Hsaio-Ling Lam

IPC分类号： A01N25/32 ,  C07D263/04 ,  C07D295/185 ,  A01N43/76 ,  A01N37/18 ,  C07C69/63 ,  C07D263/06

CPC分类号： C07D263/04 ,  A01N25/32 ,  C07D295/185 ,  Y10S106/90

摘要： N-substituted haloacyloxyacetamide compounds having the following formula: ##STR1## in which R.sub.1 is selected from the group consisting of chlorine and bromomethyl;R.sub.2 is selected from the group consisting of hydrogen, chlorine and bromine;R.sub.3 is selected from the group consisting of hydrogen, 1-4 carbon alkyl, 2-10 carbon alkenyl, and methylene malononitrile;R.sub.4 is selected from the group consisting of 1-10 carbon alkyl, 2-10 carbon alkenyl, 2-10 carbon alkynyl, and substituted phenyl wherein said substituents are chloro or 1-6 chloro alkyl; orR.sub.3 and R.sub.4 together with the nitrogen atom to which they are attached are selected from the group consisting of 4-10 carbon alkylene ring and 4-10 carbon alkyl substituted oxazolidine ring; provided that when R.sub.1 and R.sub.2 are chlorine, then R.sub.3 and R.sub.4 are other than allyl. The compounds are useful as herbicidal antidotes for protection of crops from thiocarbamate herbicidal injury.

摘要翻译： 具有下式的N-取代的卤代酰氧基乙酰胺化合物：其中R 1选自氯和溴甲基的 R2选自氢，氯和溴; R3选自氢，1-4碳烷基，2-10碳烯基和亚甲基丙二腈; R4选自1-10碳烷基，2-10碳烯基，2-10碳炔基和取代的苯基，其中所述取代基是氯或1-6氯烷基; 或R 3和R 4与它们所连接的氮原子一起选自4-10碳亚烷基环和4-10个碳烷基取代的恶唑烷环; 条件是当R 1和R 2为氯时，则R 3和R 4不是烯丙基。 该化合物可用作除草剂以保护作物免受硫代氨基甲酸酯除草损伤。