CUSTOMIZABLE TITRATION FOR AN IMPLANTABLE NEUROSTIMULATOR

    公开(公告)号:US20240399153A1

    公开(公告)日:2024-12-05

    申请号:US18731997

    申请日:2024-06-03

    Abstract: Systems and methods for customizable titration of an implantable neurostimulator are provided. A method of titrating a neurostimulation signal delivered to a patient from an implantable pulse generator includes delivering a first neurostimulation signal with a first set of parameters, increasing a first value of the first neurostimulation signal at a first rate for a first period of time while delivering the first neurostimulation signal, ceasing delivery of the first neurostimulation signal when the first value reaches a first target value, delivering a second neurostimulation signal with a second set of parameters, and increasing the second neurostimulation signal at a second rate for a second period of time while delivering the second neurostimulation signal.

    SYSTEMS AND METHODS FOR ACCELERATION-BASED SEIZURE DETECTION

    公开(公告)号:US20230126576A1

    公开(公告)日:2023-04-27

    申请号:US17508539

    申请日:2021-10-22

    Abstract: A seizure detection system comprises a sensor and a control system. The sensor is configured to detect acceleration data associated with a patient’s movements. The control system is programmed to monitor, via the sensor, the acceleration data to detect a seizure precursor event. The control system is further programmed to, upon detection of the seizure precursor event, perform a frequency analysis of the acceleration data to identify a frequency of the patient’s movements. The control system is further programmed to determine that the patient is experiencing a seizure event based on the frequency of the patient’s movements.

    Titration assist system
    7.
    发明授权

    公开(公告)号:US11633600B2

    公开(公告)日:2023-04-25

    申请号:US17136804

    申请日:2020-12-29

    Abstract: A neurostimulation system comprises a sensor and a control system. The sensor is configured to detect a cardiac physiological measure of a patient. The control system is programmed to monitor, via the sensor, the cardiac physiological measure during the treatment. The control system is further programmed to detect a change in the cardiac physiological measure during the treatment. The control system is further programmed to determine, based on the detected change in the cardiac physiological measure, a first transition time in a duty cycle of a neurostimulation signal delivered to the patient where the neurostimulation signal transitions between a stimulation OFF period and a stimulation ON period.

    Evaluation of vagus nerve stimulation using heart rate variability analysis

    公开(公告)号:US11554263B2

    公开(公告)日:2023-01-17

    申请号:US16422746

    申请日:2019-05-24

    Abstract: An implantable vagus nerve stimulation (VNS) system includes a sensor configured to measure ECG data for a patient, a stimulation subsystem configured to deliver VNS to the patient, and a control system configured to perform a heart rate variability analysis with the ECG data. In some aspects, performing the heart rate variability analysis includes measuring R-R intervals between successive R-waves for the ECG data measured during a stimulation period and a baseline period, plotting each R-R interval against an immediately preceding R-R interval for each of the stimulation period and the baseline period, and determining at least one of a standard deviation from an axis of a line perpendicular to an identity line for each of the stimulation period plot and the baseline period plot or a centroid of each of the stimulation period plot and the baseline period plot.

    Neuromodulation therapy for auto-immune and inflammatory disorders

    公开(公告)号:US11433237B2

    公开(公告)日:2022-09-06

    申请号:US16711309

    申请日:2019-12-11

    Inventor: Eric Lovett

    Abstract: The present disclosure relates to a method for modulating the nervous system in order to reduce inflammation. The method includes delivering a vagus nerve stimulation (VNS) therapy to a vagus nerve of a patient for the treatment of inflammation according to a first set of parameters. The method further includes delivering a secondary nerve stimulation (SNS) therapy to a secondary nerve of the patient for the treatment of a sleep disorder according to a second set of parameters different from the first set of parameters.

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