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    Resonance energy transfer assay with cleavage sequence and spacer
    1.
    发明授权
    Resonance energy transfer assay with cleavage sequence and spacer 有权
    具有切割序列和间隔区的共振能量转移测定

    公开(公告)号：US09303284B2

    公开(公告)日：2016-04-05

    申请号：US12059570

    申请日：2008-03-31

    申请人： Robert D. Fish ,  Min Dong

    发明人： Robert D. Fish ,  Min Dong

    IPC分类号： G01N31/00 ,  G01N33/53 ,  C12Q1/37 ,  G01N33/542 ,  G01N33/94 ,  C07K19/00 ,  C07K14/47

    CPC分类号： C12Q1/37 ,  C07K14/00 ,  C07K14/47 ,  C07K19/00 ,  C07K2319/50 ,  C07K2319/60 ,  G01N21/6428 ,  G01N33/542 ,  G01N33/9406 ,  G01N2021/6432 ,  G01N2333/952

    摘要： A molecular construct comprises a donor label, an acceptor label, a linker peptide disposed between the donor and the acceptor, the linker having a cleavage site sequence, and a spacer between at least one of (a) the donor and the cleavage site sequence and (b) the acceptor and the cleavage site sequence. Preferably, the construct is selected from the group consisting of CFP-(SGLRSRA)-SNAP-25-(SNS)-YFP (SEQ ID NO: 9), and CFP-(SGLRSRA)-synaptobrevin-(SNS)-YFP (SEQ ID NO: 10). In preferred embodiments, the linker peptide is a substrate of a botulinum neurotoxin selected from the group consisting of synaptobrevin (VAMP), syntaxin and SNAP-25, or a fragment thereof that can be recognized and cleaved by the botulinum neurotoxin. Advantageously, the spacer increases the electronic coupling between the donor label and the acceptor label relative to a corresponding construct without the spacer.

    摘要翻译： 分子构建体包括供体标记，受体标记，置于供体和受体之间的接头肽，接头具有切割位点序列，以及（a）供体和切割位点序列之间的间隔基和 （b）受体和切割位点序列。 优选地，构建体选自CFP-（SGLRSRA）-SNAP-25-（SNS）-YFP（SEQ ID NO：9）和CFP-（SGLRSRA）-Synaptobrevin-（SNS）-YFP（SEQ 编号：10）。 在优选的实施方案中，接头肽是肉毒杆菌神经毒素的底物，其选自由肉毒杆菌神经毒素可识别和切割的突触连锁蛋白（VAP），突触蛋白（S）或SNAP-25，或其片段。 有利地，间隔物相对于没有间隔物的相应构建体增加了供体标签和受体标记之间的电子偶联。

    Sulfomethylsuccinates, process for making same and compositions containing same
    2.
    发明授权
    Sulfomethylsuccinates, process for making same and compositions containing same 有权
    磺基甲基琥珀酸盐，其制备方法和含有它们的组合物

    公开(公告)号：US08853141B2

    公开(公告)日：2014-10-07

    申请号：US13505713

    申请日：2010-11-03

    申请人： Aaron Michael Brown ,  Xue Min Dong

    发明人： Aaron Michael Brown ,  Xue Min Dong

    IPC分类号： A61Q5/02 ,  A61K8/46 ,  C07C309/17 ,  C11D1/12

    CPC分类号： C07C309/17 ,  A61K8/466 ,  A61Q5/02 ,  C11D1/123

    摘要： Sulfomethylsuccinates of the formula: wherein R is an alkyl, alkenyl, alkynyl, alkoxylated alkyl, cycloalkyl, cycloalkenyl, cycloalkynyl, branched alkyl, branched alkenyl, branched alkynyl, branched alkoxylated alkyl, aromatic, substituted alkyl aromatic, substituted alkenyl aromatic or substituted alkoxylated aromatic group; M is a cation, hydrogen, amine or ammonium salt or combinations thereof, and each M may be the same as or different from the other; and n is from 1 to about 6. Processes for synthesizing the sulfomethylsuccinates are also provided. The sulfomethylsuccinates can be used as surfactants, emulsifiers, skin feel agents, film formers, rheological modifiers, solvents, release agents, lubrication agents, conditioners, and dispersants, etc.

    摘要翻译： 下式的磺基甲基琥珀酸盐：其中R是烷基，烯基，炔基，烷氧基化烷基，环烷基，环烯基，环炔基，支链烷基，支链烯基，支链炔基，支链烷氧基化烷基，芳族取代的烷基芳族，取代的烯基芳族或取代的烷氧基化芳族 组; M是阳离子，氢，胺或铵盐或其组合，并且每个M可以彼此相同或不同; 并且n为1至约6.还提供了用于合成磺基甲基琥珀酸盐的方法。 磺基甲基琥珀酸盐可用作表面活性剂，乳化剂，皮肤感觉剂，成膜剂，流变改性剂，溶剂，脱模剂，润滑剂，调理剂和分散剂等。

    User separation in space division multiple access for a multi-carrier communication system
    3.
    发明授权
    User separation in space division multiple access for a multi-carrier communication system 有权
    用于多载波通信系统的空分多址的用户分离

    公开(公告)号：US08363603B2

    公开(公告)日：2013-01-29

    申请号：US11333890

    申请日：2006-01-18

    申请人： Min Dong ,  Tingfang Ji ,  Dhananjay Ashok Gore ,  Alexei Gorokhov ,  Arak Sutivong

    发明人： Min Dong ,  Tingfang Ji ,  Dhananjay Ashok Gore ,  Alexei Gorokhov ,  Arak Sutivong

    IPC分类号： H04W4/00

    CPC分类号： H04B7/0617 ,  H04B7/0452 ,  H04W16/04 ,  H04W16/28

    摘要： Apparatuses and methodologies are described that increase system capacity in a multi-access wireless communication system. Spatial dimensions may be utilized to distinguish between multiple signals utilizing the same channel and thereby increase system capacity. Signals may be separated by applying beamforming weights based upon the spatial signature of the user device-base station pair. Grouping spatially orthogonal or disparate user devices on the same channel facilitates separation of signals and maximization of user device throughput performance. User devices may be reassigned to groups periodically or based upon changes in the spatial relationships between the user devices and the base station.

    摘要翻译： 描述了增加多址无线通信系统中的系统容量的装置和方法。 可利用空间维度来区分使用相同信道的多个信号，从而增加系统容量。 可以基于用户设备 - 基站对的空间签名应用波束成形权重来分离信号。 在相同信道上对空间正交或不同用户设备进行分组有助于信号分离和用户设备吞吐量性能的最大化。 用户设备可以周期性地或基于用户设备和基站之间的空间关系的改变重新分配给组。

    PORTABLE ELECTRONIC DEVICE WITH PENDANT ATTACHMENT SYSTEM
    4.
    发明申请
    PORTABLE ELECTRONIC DEVICE WITH PENDANT ATTACHMENT SYSTEM 失效
    便携式电子设备与吊坠附件系统

    公开(公告)号：US20120014044A1

    公开(公告)日：2012-01-19

    申请号：US12894294

    申请日：2010-09-30

    申请人： MIN DONG ,  KUAN-HUNG CHEN ,  YAO WANG

    发明人： MIN DONG ,  KUAN-HUNG CHEN ,  YAO WANG

    IPC分类号： H05K7/00

    CPC分类号： H04M1/0283 ,  G06F1/1613 ,  G06F2200/1632

    摘要： A portable electronic device includes a housing including a receptacle, a slot communicating with the receptacle and a protrusion located in the slot; a stylus releasably received in the receptacle, the stylus defining a notch and a passage communicating with the notch; and an attachment element wrapping on the protrusion and passing through the notch and the passage to extend outward from the portable electronic device.

    摘要翻译： 便携式电子设备包括：壳体，包括插座，与插座连通的槽和位于槽中的突起; 可释放地容纳在所述插座中的触针，所述触针限定凹口和与所述凹口连通的通道; 以及附接元件，其包裹在所述突起上并且穿过所述凹口和所述通道以从所述便携式电子设备向外延伸。

    Shared signaling channel
    9.
    发明申请
    Shared signaling channel 有权
    共享信令通道

    公开(公告)号：US20070097853A1

    公开(公告)日：2007-05-03

    申请号：US11261158

    申请日：2005-10-27

    申请人： Aamod Khandekar ,  Alexei Gorokhov ,  Dhananjay Gore ,  Edward Teague ,  Min Dong

    发明人： Aamod Khandekar ,  Alexei Gorokhov ,  Dhananjay Gore ,  Edward Teague ,  Min Dong

    IPC分类号： H04J11/00 ,  H04B7/216 ,  H04B7/00

    CPC分类号： H04L5/0044 ,  H04L5/0007 ,  H04L5/0048 ,  H04L5/0053

    摘要： A shared signaling channel can be used in an Orthogonal Frequency Division Multiple Access (OFDMA) communication system to provide signaling, acknowledgement, and power control messages to access terminals within the system. The shared signaling channel can be assigned to a predetermined number of sub-carriers within any frame. The assignment of a predetermined number of sub-carriers to the shared signaling channel establishes a fixed bandwidth overhead for the channel. The actual sub-carriers assigned to the channel can be varied periodically, and can vary according to a predetermined frequency hopping schedule. The amount of signal power allocated to the signaling channel can vary on a per symbol basis depending on the power requirements of the communication link. The shared signaling channel can direct each message carried on the channel to one or more access terminals. Unicast messages allow the channel power to be controlled per the needs of individual communication links.

    摘要翻译： 可以在正交频分多址（OFDMA）通信系统中使用共享信令信道，以向系统内的接入终端提供信令，确认和功率控制消息。 共享信令信道可以被分配给任何帧内的预定数量的子载波。 将预定数量的子载波分配给共享信令信道为信道建立固定的带宽开销。 分配给信道的实际子载波可以周期性地变化，并且可以根据预定的跳频调度而变化。 分配给信令信道的信号功率的量可以根据通信链路的功率要求在每个符号的基础上变化。 共享信令信道可以将信道上承载的每个消息引导到一个或多个接入终端。 单播消息允许根据各个通信链路的需要来控制信道功率。

    Shared signaling channel
    10.
    发明授权
    Shared signaling channel 有权
    共享信令通道

    公开(公告)号：US09225488B2

    公开(公告)日：2015-12-29

    申请号：US11261158

    申请日：2005-10-27

    申请人： Aamod Khandekar ,  Alexei Gorokhov ,  Dhananjay Ashok Gore ,  Edward Harrison Teague ,  Min Dong

    发明人： Aamod Khandekar ,  Alexei Gorokhov ,  Dhananjay Ashok Gore ,  Edward Harrison Teague ,  Min Dong

    IPC分类号： H04J1/00 ,  H04L5/00

    CPC分类号： H04L5/0044 ,  H04L5/0007 ,  H04L5/0048 ,  H04L5/0053

    摘要： A shared signaling channel can be used in an Orthogonal Frequency Division Multiple Access (OFDMA) communication system to provide signaling, acknowledgement, and power control messages to access terminals within the system. The shared signaling channel can be assigned to a predetermined number of sub-carriers within any frame. The assignment of a predetermined number of sub-carriers to the shared signaling channel establishes a fixed bandwidth overhead for the channel. The actual sub-carriers assigned to the channel can be varied periodically, and can vary according to a predetermined frequency hopping schedule. The amount of signal power allocated to the signaling channel can vary on a per symbol basis depending on the power requirements of the communication link. The shared signaling channel can direct each message carried on the channel to one or more access terminals. Unicast messages allow the channel power to be controlled per the needs of individual communication links.

    摘要翻译： 可以在正交频分多址（OFDMA）通信系统中使用共享信令信道，以向系统内的接入终端提供信令，确认和功率控制消息。 共享信令信道可以被分配给任何帧内的预定数量的子载波。 将预定数量的子载波分配给共享信令信道为信道建立固定的带宽开销。 分配给信道的实际子载波可以周期性地变化，并且可以根据预定的跳频调度而变化。 分配给信令信道的信号功率的量可以根据通信链路的功率要求在每个符号的基础上变化。 共享信令信道可以将信道上承载的每个消息引导到一个或多个接入终端。 单播消息允许根据各个通信链路的需要来控制信道功率。