公开(公告)号：US5994100A

公开(公告)日：1999-11-30

申请号：US865273

申请日：1997-05-29

申请人： Yuan Zhu ,  Ponnal Nambi ,  Mark A Pullen

发明人： Yuan Zhu ,  Ponnal Nambi ,  Mark A Pullen

IPC分类号： G01N33/50 ,  A61K31/7088 ,  A61K38/00 ,  A61K45/00 ,  A61K48/00 ,  A61P1/16 ,  A61P9/10 ,  A61P13/02 ,  A61P13/12 ,  A61P15/00 ,  A61P19/02 ,  A61P29/00 ,  A61P35/00 ,  A61P43/00 ,  C07K16/40 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/00 ,  C12N9/10 ,  C12N15/09 ,  C12N15/54 ,  C12P21/08 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/15 ,  C12P21/06 ,  C07H21/04 ,  C12N1/20 ,  C12N15/00

CPC分类号： C12N9/1051 ,  A61K38/00

摘要： HOEFC11 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HOEFC11 polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal failure, inflammatory diseases, myocardial ischemia, cancer, rheumatoid arthritis, cirrhotic liver disease, among others, and diagnostic assays for such conditions.

公开(公告)号：US06350446B1

公开(公告)日：2002-02-26

申请号：US09385174

申请日：1999-08-30

申请人： Yuan Zhu ,  Ponnal Nambi ,  Mark A Pullen

发明人： Yuan Zhu ,  Ponnal Nambi ,  Mark A Pullen

IPC分类号： A61K3843

CPC分类号： C12N9/1051 ,  A61K38/00

摘要： HOEFC11 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HOEFC11 polypeptides and polynucleotides in the design of protocols for the treatment of chronic renal failure, inflammatory diseases, myocardial ischemia, cancer, rheumatoid arthritis, cirrhotic liver disease, among others, and diagnostic assays for such conditions.

摘要翻译： 公开了HOEFC11多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在设计用于治疗慢性肾功能衰竭，炎性疾病，心肌缺血，癌症，类风湿性关节炎，肝硬化肝病等的方案中用于HOEFC11多肽和多核苷酸的方法以及用于这些病症的诊断测定法。