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公开(公告)号：US20060083752A1
公开(公告)日：2006-04-20
申请号：US11166905
申请日：2005-06-23
申请人： Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
发明人： Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
IPC分类号： A61K39/02 , C07H21/04 , C12N15/74 , C07K14/195 , C12N1/21
CPC分类号： C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要： This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译： 本发明涉及新鉴定的葡萄球菌多核苷酸，由这种多核苷酸编码的多肽，这种多核苷酸和多肽的用途，以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号：US20070009546A1
公开(公告)日：2007-01-11
申请号：US11403784
申请日：2006-04-13
申请人： Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
发明人： Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
IPC分类号： A61K39/02 , C07H21/04 , C12P21/06 , C12N1/21 , C07K14/315
CPC分类号： C12N9/1077 , A61K38/00 , A61K39/00 , C07K14/3156 , C07K2319/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12Y207/01002
摘要： The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了编码这种多肽的新型多肽和多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用这些多肽筛选抗菌化合物的方法。
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公开(公告)号：US20060115831A1
公开(公告)日：2006-06-01
申请号：US11200907
申请日：2005-08-10
申请人： Sanjoy Biswas , James Brown , Martin Burnham , Alisori Chalker , David Holmes , Karen Ingraham , Thomas Mathie , Richard Warren , Magdalena Zalacain
发明人： Sanjoy Biswas , James Brown , Martin Burnham , Alisori Chalker , David Holmes , Karen Ingraham , Thomas Mathie , Richard Warren , Magdalena Zalacain
IPC分类号： C12Q1/68 , C07H21/04 , C07K14/315
CPC分类号： C12N9/1205 , C07K14/3156 , C12Q1/6883 , G01N33/68 , Y02A50/396
摘要： The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
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公开(公告)号：US20080076709A1
公开(公告)日：2008-03-27
申请号：US11698250
申请日：2007-01-25
申请人： Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
发明人： Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
CPC分类号： C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要： This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译： 本发明涉及新鉴定的葡萄球菌多核苷酸，由这种多核苷酸编码的多肽，这种多核苷酸和多肽的用途，以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号：US20060223082A1
公开(公告)日：2006-10-05
申请号：US11271616
申请日：2005-11-10
IPC分类号： C40B30/06 , C12Q1/68 , G01N33/554 , G06F19/00 , C07H21/04 , C12N1/21 , C07K14/31 , C07K16/12
摘要： The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
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公开(公告)号：US20050032161A1
公开(公告)日：2005-02-10
申请号：US10818093
申请日：2004-04-05
申请人： Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
发明人： Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
IPC分类号： C12N15/09 , A61K38/00 , A61K39/00 , A61K39/09 , A61K39/395 , A61K45/00 , A61K48/00 , A61P9/00 , A61P11/00 , A61P25/00 , A61P27/02 , A61P27/16 , A61P31/04 , A61P43/00 , C07K14/315 , C07K16/12 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/10 , C12N9/12 , C12N9/78 , C12N9/80 , C12P21/02 , C12P21/08 , C12Q1/02 , C12Q1/68 , C12R1/46 , C07H21/04
CPC分类号： C12N9/1077 , A61K38/00 , A61K39/00 , C07K14/3156 , C07K2319/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12Y207/01002
摘要： The invention provides xanthine phosphoribosyl transferase polypeptides and DNA (RNA) encoding xanthine phosphoribosyl transferase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing xanthine phosphoribosyl transferase polypeptides to screen for antibacterial compounds.
摘要翻译： 本发明提供了黄嘌呤磷酸核糖基转移酶多肽和编码黄嘌呤磷酸核糖转移酶多肽的DNA（RNA）和通过重组技术产生这种多肽的方法。 还提供了利用黄嘌呤磷酸核糖转移酶多肽筛选抗菌化合物的方法。
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