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公开(公告)号:US20060115831A1
公开(公告)日:2006-06-01
申请号:US11200907
申请日:2005-08-10
申请人: Sanjoy Biswas , James Brown , Martin Burnham , Alisori Chalker , David Holmes , Karen Ingraham , Thomas Mathie , Richard Warren , Magdalena Zalacain
发明人: Sanjoy Biswas , James Brown , Martin Burnham , Alisori Chalker , David Holmes , Karen Ingraham , Thomas Mathie , Richard Warren , Magdalena Zalacain
IPC分类号: C12Q1/68 , C07H21/04 , C07K14/315
CPC分类号: C12N9/1205 , C07K14/3156 , C12Q1/6883 , G01N33/68 , Y02A50/396
摘要: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
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公开(公告)号:US20080076709A1
公开(公告)日:2008-03-27
申请号:US11698250
申请日:2007-01-25
申请人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
发明人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
CPC分类号: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译: 本发明涉及新鉴定的葡萄球菌多核苷酸,由这种多核苷酸编码的多肽,这种多核苷酸和多肽的用途,以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号:US20060083752A1
公开(公告)日:2006-04-20
申请号:US11166905
申请日:2005-06-23
申请人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
发明人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
IPC分类号: A61K39/02 , C07H21/04 , C12N15/74 , C07K14/195 , C12N1/21
CPC分类号: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译: 本发明涉及新鉴定的葡萄球菌多核苷酸,由这种多核苷酸编码的多肽,这种多核苷酸和多肽的用途,以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号:USD944610S1
公开(公告)日:2022-03-01
申请号:US29750310
申请日:2020-09-12
申请人: Richard Warren
设计人: Richard Warren
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公开(公告)号:US5025242A
公开(公告)日:1991-06-18
申请号:US558324
申请日:1990-07-24
摘要: An oven control for self-cleaning ovens provides a hydraulic sensing system having a wafer-like bellows. The position of the bellows is adjusted by a face cam on a control shaft in the BAKE and BROIL modes of operation. The bellows also controls the temperature of the oven for SELF-CLEANING. However, the face cam does not determine the SELF-CLEANING temperature. A door lock operator switch is also operated by the bellows, but is connected so that the adjusted position of the bellows does not affect the door lock operating temperature. Three separate calibration adjustments are provided. The first calibrates the operating temperature in the BAKE and BROIL modes of operation. The second calibrates the SELF-CLEANING temperature, and the third calibrates the door lock operating temperature. A bimetal ambient temperature compensator is provided to compensate for variations in the ambient temperature of the control.
摘要翻译: 用于自清洁烤箱的烤箱控制器提供具有晶片状波纹管的液压感测系统。 波纹管的位置由BAKE和BROIL操作模式中的控制轴上的面凸轮调节。 波纹管还可以控制烘箱的自动清洗温度。 但是,面凸轮不能确定自清洁温度。 门锁操作开关也由波纹管操作,但是被连接,使得波纹管的调节位置不影响门锁的工作温度。 提供三个单独的校准调整。 首先在BAKE和BROIL操作模式下校准工作温度。 第二个校准SELF-CLEANING温度,第三个校准门锁的工作温度。 提供双金属环境温度补偿器来补偿控制器的环境温度的变化。
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公开(公告)号:US4292725A
公开(公告)日:1981-10-06
申请号:US29516
申请日:1979-04-12
申请人: Leif Larsson , Richard Warren
发明人: Leif Larsson , Richard Warren
CPC分类号: C22C47/00 , B23K20/00 , B23K20/14 , C22C47/068 , Y10T29/49801
摘要: A method of producing an object of fiber reinforced metal material, in which method a plurality of fibers or fiber bundles of a material of high strength are arranged at spaced positions, and a matrix material, preferably metal or metal alloy, is brought to closely surround each fiber or fiber bundle and is formed to a shape corresponding to the desired shape of the object. Earlier attempts to produce objects of fiber reinforced metal material have encountered problem regarding the arrangement of the fibers in a uniform pattern and in obtaining a predetermined volume fraction of the fibers in the completed object. According to the invention each fiber bundle is inserted in a tube, made of the matrix material and having suitable wall thickness to give the desired spacing between the fibers or fiber bundles, the tubes are placed in a casing, which is intended to give the object the desired outer configuration and preferably is made of the matrix material, and the casing with the tubes and fibers or fiber bundles arranged therein is subjected to hot isostatic pressing at high pressure and high temperature during an interval of time that is sufficient to give plastic deformation of the material to a substantially dense material.
摘要翻译: 一种制造纤维增强金属材料的方法,其中将多根高强度材料的纤维或纤维束布置在间隔位置,并且将基质材料(优选金属或金属合金)紧密地包围 每个纤维或纤维束,并且形成为对应于物体的期望形状的形状。 早期尝试生产纤维增强金属材料的目的已经遇到了关于以均匀图案布置纤维并获得完成物体中纤维的预定体积分数的问题。 根据本发明,每个纤维束被插入由基质材料制成并具有合适的壁厚度的管中,以在纤维或纤维束之间产生所需的间隔,将管放置在壳体中,该壳体旨在给予物体 期望的外部构造,并且优选地由基质材料制成,并且具有布置在其中的管和纤维或纤维束的壳体在足以产生塑性变形的时间间隔内在高压和高温下进行热等静压 的材料制成基本致密的材料。
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公开(公告)号:US20220266430A1
公开(公告)日:2022-08-25
申请号:US17399111
申请日:2021-08-11
申请人: Richard Warren
发明人: Richard Warren
IPC分类号: B25B27/02
摘要: Current EvoPEX connector fittings offer numerous advantages over brass fitting counterparts. However, EvoPEX connector fitting's non-removable design can lead to increased labor and costs. The proposed removal tool is designed to remove push-to-connect fittings from various fluid conduits and includes an external malleable clamping flange and an internal metallic release sheet, adaptable for sealing engagement with a fluid conduit outer wall. Once the metallic release sheet circumscribes the appropriate, fluid conduit, the user pivotally slides the conduit removal tool laterally toward the EvoPEX connector fitting. Insertion of the metallic release sheet between the fluid conduit and the EvoPEX connector fitting depresses the internal locking collar. This depression mechanism prevents structural damage to PEX fluid conduit, thereby permitting reuse of the associated fluid conduit as not previously possible. Once inserted, the user may mechanically decouple the EvoPEX connector fitting from the fluid conduit through manual separation.
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公开(公告)号:US06242249B1
公开(公告)日:2001-06-05
申请号:US09414664
申请日:1999-10-07
申请人: Martin Karl Russel Burnham , Andrew Fosberry , John Edward Hodgson , Deborah Dee Jaworski , Elizabeth J Lawlor , Martin Rosenberg , Christopher Michael Traini , Min Wang , Judith Ward , Richard Warren
发明人: Martin Karl Russel Burnham , Andrew Fosberry , John Edward Hodgson , Deborah Dee Jaworski , Elizabeth J Lawlor , Martin Rosenberg , Christopher Michael Traini , Min Wang , Judith Ward , Richard Warren
IPC分类号: C07H2104
CPC分类号: C07K14/31 , A61K38/00 , A61K39/00 , A61K2039/51 , C12N9/90
摘要: The invention provides tig polypeptides and polynucleotides encoding tig polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tig polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了tig多肽和编码tig多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用tig多肽筛选抗菌化合物的方法。
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公开(公告)号:USD262732S
公开(公告)日:1982-01-19
申请号:US45189
申请日:1979-06-04
申请人: John E. Warren , Richard Warren
设计人: John E. Warren , Richard Warren
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公开(公告)号:US06348342B1
公开(公告)日:2002-02-19
申请号:US09757014
申请日:2001-01-09
申请人: Karen M O'Dwyer , Richard Warren , Caroline Perry
发明人: Karen M O'Dwyer , Richard Warren , Caroline Perry
IPC分类号: A61K3900
CPC分类号: C12N9/14 , A61K39/00 , A61K2039/51
摘要: The invention provides secA2 polypeptides and DNA (RNA) encoding secA2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing secA2 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了secA2多肽和编码secA2多肽的DNA(RNA)和通过重组技术产生这种多肽的方法。 还提供了利用secA2多肽筛选抗菌化合物的方法。
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