公开(公告)号：US07294249B2

公开(公告)日：2007-11-13

申请号：US10355320

申请日：2003-01-31

申请人： Shady Gawad ,  Martin Wüthrich ,  Philippe Renaud

发明人： Shady Gawad ,  Martin Wüthrich ,  Philippe Renaud

IPC分类号： G01N27/02 ,  G01F1/64

CPC分类号： G01N15/1056 ,  B01L3/502761 ,  B01L3/502784 ,  B01L2200/0636 ,  B01L2200/0647 ,  B01L2400/0415 ,  B03C5/026 ,  G01N15/1031 ,  G01N27/02 ,  G01N2015/1006

摘要： Microtechnologically prepared component as a flow cytometer. The component contains a preparation area to specifically influence and separate the particles, preferably by dielectrophoresis, a measuring channel area for characterizing the particles, and a sorting area for sorting the particles identified in the measuring channel area by dielectrophoresis. The sorting includes switching elements which permit active guidance of the particles into two or more subchannels corresponding to the criteria which have been registered in the measuring channel area. With a component configured in this way for the use of a flow cytometer, quick and precise sorting of particles, in particular biological cells in a suspension, can be implemented.

摘要翻译： 微技术制备的组分作为流式细胞仪。 组分包含用于特别影响和分离颗粒的制备区域，优选通过介电电泳，用于表征颗粒的测量通道区域和用于通过介电电泳分选在测量通道区域中识别的颗粒的分选区域。 排序包括允许主动地将颗粒引导到对应于已经登记在测量通道区域中的标准的两个或更多个子通道中的开关元件。 通过以这种方式配置以使用流式细胞仪的组件，可以实现对悬浮液中的颗粒，特别是生物细胞的快速和精确的分选。