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    Microscope apparatus
    1.
    发明授权
    Microscope apparatus 有权
    显微镜装置

    公开(公告)号：US08144396B2

    公开(公告)日：2012-03-27

    申请号：US12060994

    申请日：2008-04-02

    申请人： Masaharu Tomioka ,  Akinori Araya ,  Toshiyuki Hattori ,  Yasunari Matsukawa ,  Tatsuo Nakata

    发明人： Masaharu Tomioka ,  Akinori Araya ,  Toshiyuki Hattori ,  Yasunari Matsukawa ,  Tatsuo Nakata

    IPC分类号： G02B21/26

    CPC分类号： G02B21/33

    摘要： An image can be prevented from becoming unclear over time during long-term observation. The invention provides a microscope apparatus including a specimen container for containing a specimen; an objective lens disposed opposite the specimen container for collecting light from the specimen in the specimen container; an immersion-liquid supplying unit for supplying immersion liquid to a space between the objective lens and the specimen container; and an immersion-liquid removing unit for removing the immersion liquid from the space between the objective lens and the specimen container. The immersion-liquid removing unit includes a nozzle for ejecting compressed air to the space between the objective lens and the specimen container.

    摘要翻译： 在长期观察期间，可以防止图像变得不清楚。 本发明提供了一种显微镜装置，其包括：容纳样本的检体容器; 与样本容器相对设置的用于收集来自样本容器中的样本的光的物镜; 浸没液供给单元，其向所述物镜和所述检体容器之间的空间供给浸渍液; 以及用于从物镜和样本容器之间的空间中去除浸液的浸液清除单元。 浸液清除单元包括用于将压缩空气喷射到物镜和样本容器之间的空间的喷嘴。

    Laser scanning microscope
    2.
    发明授权
    Laser scanning microscope 有权
    激光扫描显微镜

    公开(公告)号：US07485876B2

    公开(公告)日：2009-02-03

    申请号：US11711407

    申请日：2007-02-27

    申请人： Masaharu Tomioka ,  Tatsuo Nakata ,  Hiroshi Sasaki

    发明人： Masaharu Tomioka ,  Tatsuo Nakata ,  Hiroshi Sasaki

    IPC分类号： G01J1/58

    CPC分类号： G02B21/0076 ,  G02B21/0064 ,  G02B21/0068

    摘要： A laser scanning microscope includes an exciting observation light source, a stimulation light source, a first scanning portion that two-dimensionally scans the exciting observation light across a specimen, a second scanning portion that sets an incident position of the stimulation light on the specimen, an optical path combining portion that brings the exciting observation light and the stimulation light to an identical optical path, an objective lens that irradiates the specimen with the exciting observation light and/or the stimulation light while collecting fluorescence light emitted from the specimen, and a detecting portion that detects the collected fluorescence light, the optical path combining portion being disposed so as to be in an optically conjugate relationship with the first scanning portion and the second scanning portion.

    摘要翻译： 激光扫描显微镜包括激发观察光源，刺激光源，二维地扫描穿过样本的激发观察光的第一扫描部分，将刺激光的入射位置设定在样本上的第二扫描部， 将激发观察光和刺激光带入相同的光路的光路组合部，在收集从样本发出的荧光的同时照射具有激发观察光和/或刺激光的样本的物镜， 检测部分，其检测所收集的荧光，所述光路组合部分设置成与所述第一扫描部分和所述第二扫描部分处于光学共轭关系。

    MICROSCOPE APPARATUS
    3.
    发明申请
    MICROSCOPE APPARATUS 有权
    MICROSCOPE设备

    公开(公告)号：US20080252967A1

    公开(公告)日：2008-10-16

    申请号：US12060994

    申请日：2008-04-02

    申请人： Masaharu Tomioka ,  Akinori Araya ,  Toshiyuki Hattori ,  Yasunari Matsukawa ,  Tatsuo Nakata

    发明人： Masaharu Tomioka ,  Akinori Araya ,  Toshiyuki Hattori ,  Yasunari Matsukawa ,  Tatsuo Nakata

    IPC分类号： G02B21/34

    CPC分类号： G02B21/33

    摘要： An image can be prevented from becoming unclear over time during long-term observation. The invention provides a microscope apparatus including a specimen container for containing a specimen; an objective lens disposed opposite the specimen container for collecting light from the specimen in the specimen container; an immersion-liquid supplying unit for supplying immersion liquid to a space between the objective lens and the specimen container; and an immersion-liquid removing unit for removing the immersion liquid from the space between the objective lens and the specimen container. The immersion-liquid removing unit includes a nozzle for ejecting compressed air to the space between the objective lens and the specimen container.

    摘要翻译： 在长期观察期间，可以防止图像变得不清楚。 本发明提供了一种显微镜装置，其包括：容纳样本的检体容器; 与样本容器相对设置的用于收集来自样本容器中的样本的光的物镜; 浸没液供给单元，其向所述物镜和所述检体容器之间的空间供给浸渍液; 以及用于从物镜和样本容器之间的空间中去除浸液的浸液清除单元。 浸液清除单元包括用于将压缩空气喷射到物镜和样本容器之间的空间的喷嘴。

    Laser scanning microscope
    4.
    发明申请
    Laser scanning microscope 有权
    激光扫描显微镜

    公开(公告)号：US20070205378A1

    公开(公告)日：2007-09-06

    申请号：US11711407

    申请日：2007-02-27

    申请人： Masaharu Tomioka ,  Tatsuo Nakata ,  Hiroshi Sasaki

    发明人： Masaharu Tomioka ,  Tatsuo Nakata ,  Hiroshi Sasaki

    IPC分类号： G01J1/58 ,  F21V9/16

    CPC分类号： G02B21/0076 ,  G02B21/0064 ,  G02B21/0068

    摘要： A laser scanning microscope provides advantages that replacement of any optical element becomes unnecessary, and ease of operation and positioning repeatability of light stimulation are improved. The laser scanning microscope includes an exciting observation light source, a stimulation light source, a first scanning portion that two-dimensionally scans the exciting observation light across a specimen, a second scanning portion that sets an incident position of the stimulation light on the specimen, an optical path combining portion that brings the exciting observation light and the stimulation light to an identical optical path, an objective lens that irradiates the specimen with the exciting observation light and/or the stimulation light while converging fluorescence light emitted from the specimen, and a detecting portion that detects the converged fluorescence light, the optical path combining portion being disposed so as to be in an optically conjugate relationship with the first scanning portion and the second scanning portion.

    摘要翻译： 激光扫描显微镜提供了不需要更换任何光学元件的优点，并且提高了光刺激的操作和定位重复性的容易性。 激光扫描显微镜包括激发观察光源，刺激光源，二维地扫描穿过样本的激发观察光的第一扫描部分，将刺激光的入射位置设定在样本上的第二扫描部， 将激发观察光和刺激光带到相同的光路的光路组合部，使从激光观察光和/或刺激光照射到样本的物镜同时会聚从样本发出的荧光，以及 检测所述会聚的荧光的检测部，所述光路组合部被配置为与所述第一扫描部和所述第二扫描部成为光学共轭关系。

    Device for inspecting raised fiber state of web members of sanitary articles and method of the same
    5.
    发明授权
    Device for inspecting raised fiber state of web members of sanitary articles and method of the same 有权
    用于检查卫生用品的织物的纤维状态的装置及其方法

    公开(公告)号：US09207187B2

    公开(公告)日：2015-12-08

    申请号：US14345174

    申请日：2012-09-06

    申请人： Masaharu Tomioka

    发明人： Masaharu Tomioka

    IPC分类号： H04N7/18 ,  G01N21/898 ,  G01N21/88 ,  G01N21/84

    CPC分类号： G01N21/898 ,  G01N21/8851 ,  G01N21/8983 ,  G01N2021/8444

    摘要： A device for inspecting a raised fiber state of a web member of a sanitary article, the web member having, on at least one face, fiber raisable parts that come off from the one face in a predetermined dispersed arrangement pattern, new exposed parts being created on the one face when the fiber raisable parts come off to be raised, wherein the inspection device includes an image capturing processing part that captures an image of the one face and creates as a planar image data, a data of a planar image of the one face, a binarization processing part that performs, when creating a binarized image based on the planar image data, a binarization process so that areas in which images of the new exposed parts in the planar image are captured, are included in an image specified by one value of two values in the binarized image, and a quality judgment processing part that performs quality judgment of the raised fiber state based on a value indicating a size of the image.

    摘要翻译： 一种用于检查卫生用品的网状构件的升高的纤维状态的装置，所述腹板构件在至少一个面上具有以预定的分散布置图案从一个面脱落的纤维可升高部件，创建新的暴露部分 在纤维可升高部件脱落升高的一个面上，其特征在于，所述检查装置具备拍摄所述一面的图像并形成为平面图像数据的图像拍摄处理部，所述图像的平面图像的数据 面部，二值化处理部，其在基于平面图像数据创建二值化图像时执行二值化处理，使得捕获平面图像中的新曝光部分的图像的区域被包括在由一个 二值化图像中的两个值的值;以及质量判断处理部，其基于表示图像的大小的值，进行升高的光纤状态的质量判定。

    Scanning microscope and adjusting method for the same
    7.
    发明申请
    Scanning microscope and adjusting method for the same 有权
    扫描显微镜和调整方法相同

    公开(公告)号：US20080259442A1

    公开(公告)日：2008-10-23

    申请号：US12079153

    申请日：2008-03-25

    申请人： Yasunari Matsukawa ,  Masaharu Tomioka ,  Akinori Araya ,  Toshiyuki Hattori

    发明人： Yasunari Matsukawa ,  Masaharu Tomioka ,  Akinori Araya ,  Toshiyuki Hattori

    IPC分类号： G02B21/06

    CPC分类号： G02B21/008 ,  G02B21/365

    摘要： A scanning microscope includes an objective lens for focusing illumination light onto a specimen; a scanning device for deflecting and scanning the illumination light; a pupil-projection optical system for illuminating a pupil of the objective lens with the scanned illumination light; and a total-magnification specifying unit for specifying a total magnification. An optical-system selecting unit changes at least one of the objective lens and the pupil-projection optical system such that a magnification of an optical system including the objective lens and the pupil-projection optical system is equal to or less than the total magnification specified by the total-magnification specifying unit and that the numerical aperture of the optical system is maximized. A deflection-angle determination unit determines a deflection angle of the illumination light deflected by the scanning device based on the ratio of the magnification of the optical system to the total magnification to achieve the total magnification.

    摘要翻译： 扫描显微镜包括用于将照明光聚焦到样本上的物镜; 用于偏转和扫描照明光的扫描装置; 用于利用扫描的照明光照射物镜的光瞳的光瞳投影光学系统; 以及用于指定总放大率的总放大率指定单元。 光学系统选择单元改变物镜和瞳孔投影光学系统中的至少一个，使得包括物镜和瞳孔投影光学系统的光学系统的放大倍数等于或小于指定的总倍率 通过总倍率指定单元，并且光学系统的数值孔径最大化。 偏转角确定单元基于光学系统的倍率与总放大率的比率确定由扫描装置偏转的照明光的偏转角，以实现总放大率。

    Laser microscope
    9.
    发明授权
    Laser microscope 失效
    激光显微镜

    公开(公告)号：US06855941B1

    公开(公告)日：2005-02-15

    申请号：US09265183

    申请日：1999-03-09

    申请人： Masaharu Tomioka

    发明人： Masaharu Tomioka

    IPC分类号： G01N21/64 ,  G02B21/16 ,  G02B21/24

    CPC分类号： G01N21/6458 ,  G02B21/16 ,  G02B21/248

    摘要： A multiphoton excitation scanning laser microscope employs a laser beam source for oscillating a pulse laser beam having a wavelength range. A multiphoton excitation phenomenon takes place in a sample irradiated with the laser beam so as to emit a fluorescent light. An optical system for forming an optical path of the laser beam includes a pre-chirp compensator, a scanning optical unit and a plurality of objective lenses differing from each other in magnification and capable of being selectively arranged on the optical path. The optical system also includes a correcting mechanism for causing the pulse width of the laser beam to be constant on a cross section of the sample in the case of selecting any of the objective lenses. The correcting mechanism includes a plurality of correcting plates capable of being selectively arranged on the optical path.

    摘要翻译： 多光子激发扫描激光显微镜使用激光束源来振荡具有波长范围的脉冲激光束。 在用激光束照射的样品中发生多光子激发现象以发出荧光。 用于形成激光束的光路的光学系统包括预啁啾补偿器，扫描光学单元和放大率彼此不同的能够选择性地布置在光路上的多个物镜。 光学系统还包括校正机构，用于在选择任何物镜的情况下使得激光束的脉冲宽度在样品的横截面上恒定。 校正机构包括能够选择性地布置在光路上的多个校正板。