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    Remedies
    1.
    发明申请
    Remedies 审中-公开
    补救措施

    公开(公告)号：US20060199774A1

    公开(公告)日：2006-09-07

    申请号：US11408946

    申请日：2006-04-24

    申请人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K31/366 ,  A61K31/7048

    CPC分类号： A61K31/7048 ,  A23K20/116 ,  A23K20/163 ,  A23L33/105 ,  A61K31/366 ,  A61K31/37 ,  C07H17/04 ,  C07H17/075

    摘要： The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring enhancement of NGF production, wherein the compound has a coumarin and/or chroman backbone. Since no toxicity is especially found in the effective ingredient of the present invention, and there is no risk of incidence of adverse actions, the treatment or the like of the above disease can be safely and appropriately carried out.

    摘要翻译： 本发明涉及一种药物，食品，饮料或饲料，其各自包含作为有效成分的具有NGF生产增强作用的化合物，其有效治疗，改善症状，预防等 需要增强NGF生产的疾病，其中所述化合物具有香豆素和/或色胺骨架。 由于在本发明的有效成分中没有特别的毒性，并且不存在不良反应的发生风险，所以可以安全，适当地进行上述疾病的治疗等。

    Remedies
    3.
    发明授权
    Remedies 失效
    补救措施

    公开(公告)号：US07268160B2

    公开(公告)日：2007-09-11

    申请号：US10182193

    申请日：2001-01-26

    申请人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Eiji Kobayashi ,  Tuo-Ping Li ,  Suzu Deguchi ,  Eiji Nishiyama ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Eiji Kobayashi ,  Tuo-Ping Li ,  Suzu Deguchi ,  Eiji Nishiyama ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K31/35 ,  A61K31/22 ,  C07D307/02 ,  C07C67/02

    CPC分类号： A61K31/7004 ,  A23L33/10 ,  A61K31/12 ,  A61K31/216 ,  A61K31/222 ,  A61K31/352

    摘要： The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production, each comprising as an effective ingredient a specified compound or a salt thereof having enhancing activity for nerve growth factor production; a method for enhancing nerve growth factor production, comprising administering to a mammal the above-mentioned compound or a salt thereof; and use of the above-mentioned compound or a salt thereof in the preparation of a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production. In addition, the present invention provides novel compounds having enhancing activity for nerve growth factor production.

    摘要翻译： 本发明提供了需要增强神经生长因子产生的疾病的治疗剂或预防剂，用于神经生长因子产生的增强剂或用于增强神经生长因子产生的食品，饮料或饲料，其各自包含作为有效成分 具有增强神经生长因子生成活性的特定化合物或其盐; 一种用于增强神经生长因子产生的方法，包括向哺乳动物施用上述化合物或其盐; 以及上述化合物或其盐在制备需要增强神经生长因子产生的疾病的治疗剂或预防剂，用于神经生长因子产生的增强剂或食品，饮料或饲料中的用途 增强神经生长因子的产生。 此外，本发明提供了具有增强神经生长因子产生活性的新型化合物。