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98 条记录 (耗时 0.035 秒)

    Remedies
    1.
    发明申请
    Remedies 审中-公开
    补救措施

    公开(公告)号：US20060199774A1

    公开(公告)日：2006-09-07

    申请号：US11408946

    申请日：2006-04-24

    申请人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K31/366 ,  A61K31/7048

    CPC分类号： A61K31/7048 ,  A23K20/116 ,  A23K20/163 ,  A23L33/105 ,  A61K31/366 ,  A61K31/37 ,  C07H17/04 ,  C07H17/075

    摘要： The present invention relates to a medicament, a food, a beverage or a feed, each comprising as an effective ingredient a compound having an enhancing action for NGF production, which is effective for a treatment, an amelioration of symptom, prevention or the like of a disease requiring enhancement of NGF production, wherein the compound has a coumarin and/or chroman backbone. Since no toxicity is especially found in the effective ingredient of the present invention, and there is no risk of incidence of adverse actions, the treatment or the like of the above disease can be safely and appropriately carried out.

    摘要翻译： 本发明涉及一种药物，食品，饮料或饲料，其各自包含作为有效成分的具有NGF生产增强作用的化合物，其有效治疗，改善症状，预防等 需要增强NGF生产的疾病，其中所述化合物具有香豆素和/或色胺骨架。 由于在本发明的有效成分中没有特别的毒性，并且不存在不良反应的发生风险，所以可以安全，适当地进行上述疾病的治疗等。

    Remedies
    3.
    发明授权
    Remedies 失效
    补救措施

    公开(公告)号：US07268160B2

    公开(公告)日：2007-09-11

    申请号：US10182193

    申请日：2001-01-26

    申请人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Eiji Kobayashi ,  Tuo-Ping Li ,  Suzu Deguchi ,  Eiji Nishiyama ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Hiromu Ohnogi ,  Masahiro Shiraga ,  Eiji Kobayashi ,  Tuo-Ping Li ,  Suzu Deguchi ,  Eiji Nishiyama ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K31/35 ,  A61K31/22 ,  C07D307/02 ,  C07C67/02

    CPC分类号： A61K31/7004 ,  A23L33/10 ,  A61K31/12 ,  A61K31/216 ,  A61K31/222 ,  A61K31/352

    摘要： The present invention provides a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production, each comprising as an effective ingredient a specified compound or a salt thereof having enhancing activity for nerve growth factor production; a method for enhancing nerve growth factor production, comprising administering to a mammal the above-mentioned compound or a salt thereof; and use of the above-mentioned compound or a salt thereof in the preparation of a therapeutic agent or prophylactic agent for a disease that requires enhancement of nerve growth factor production, an enhancer for nerve growth factor production, or a food, beverage or feed for enhancing nerve growth factor production. In addition, the present invention provides novel compounds having enhancing activity for nerve growth factor production.

    摘要翻译： 本发明提供了需要增强神经生长因子产生的疾病的治疗剂或预防剂，用于神经生长因子产生的增强剂或用于增强神经生长因子产生的食品，饮料或饲料，其各自包含作为有效成分 具有增强神经生长因子生成活性的特定化合物或其盐; 一种用于增强神经生长因子产生的方法，包括向哺乳动物施用上述化合物或其盐; 以及上述化合物或其盐在制备需要增强神经生长因子产生的疾病的治疗剂或预防剂，用于神经生长因子产生的增强剂或食品，饮料或饲料中的用途 增强神经生长因子的产生。 此外，本发明提供了具有增强神经生长因子产生活性的新型化合物。

    Extract from plant of japanese parsley family and process for producing the same
    9.
    发明申请
    Extract from plant of japanese parsley family and process for producing the same 审中-公开
    从日本欧芹系列植物提取物及其生产方法

    公开(公告)号：US20070092587A1

    公开(公告)日：2007-04-26

    申请号：US10561431

    申请日：2004-06-18

    申请人： Hiromu Ohnogi ,  Katsumi Sugiyama ,  Nobuko Muraki ,  Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Hiromu Ohnogi ,  Katsumi Sugiyama ,  Nobuko Muraki ,  Tatsuji Enoki ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K36/232

    CPC分类号： A61K36/232 ,  A23L2/02 ,  A23V2002/00 ,  A23V2250/21 ,  A23V2200/328

    摘要： The present invention provides an extract obtainable by extracting a plant belonging to Umbelliferae, or a processed product thereof, with a water-containing alcohol; a process for preparing the extract; a therapeutic agent or prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response and/or diabetic complications, characterized in that the therapeutic agent or prophylactic agent comprises as an effective ingredient the extract as defined above; an agent for an insulin-mimetic action, characterized in that the agent comprises as an effective ingredient the extract as defined above; a food, beverage or feed, comprising the extract as defined above; an agent for enhancing glucose uptake into a cell, characterized in that the agent comprises as an effective ingredient the extract as defined above; to an agent for inducing differentiation into an adipocyte, characterized in that the agent comprises as an effective ingredient the extract as defined above; and an inhibitory agent for aldose reductase, characterized in that the agent comprises as an effective ingredient the extract as define above.

    摘要翻译： 本发明提供通过用含水醇提取属于伞形赤霉属的植物或其加工产物而获得的提取物; 一种制备提取物的方法; 用于伴随胰岛素或胰岛素反应量和/或糖尿病并发症的异常的疾病的治疗剂或预防剂，其特征在于所述治疗剂或预防剂包含作为有效成分的上述提取物; 用于胰岛素模拟作用的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 包含上述提取物的食品，饮料或饲料; 用于增强葡萄糖摄入细胞的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 涉及诱导分化为脂肪细胞的药剂，其特征在于所述药剂包含如上所定义的提取物作为有效成分; 以及醛糖还原酶抑制剂，其特征在于，所述药剂含有作为有效成分的上述定义的提取物。

    Remedy
    10.
    发明申请
    Remedy 审中-公开
    补救

    公开(公告)号：US20060216362A1

    公开(公告)日：2006-09-28

    申请号：US10557184

    申请日：2004-05-14

    申请人： Tatsuji Enoki ,  Kinuko Ogawa ,  Hiromu Ohnogi ,  Nobuko Muraki ,  Yoko Kudo ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Tatsuji Enoki ,  Kinuko Ogawa ,  Hiromu Ohnogi ,  Nobuko Muraki ,  Yoko Kudo ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： A61K36/9066 ,  A61K36/886 ,  A61K36/282 ,  A61K36/28 ,  A61K36/704 ,  A61K36/185

    CPC分类号： A61K36/896 ,  A23K20/10 ,  A23L33/105 ,  A61K36/185 ,  A61K36/28 ,  A61K36/282 ,  A61K36/287 ,  A61K36/70 ,  A61K36/704 ,  A61K36/886 ,  A61K36/906 ,  A61K36/9066

    摘要： The present invention relates to a therapeutic agent and prophylactic agent for a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for an insulin-mimetic action, a food, beverage and feed for treating a preventing a disease accompanying an abnormality in an amount of insulin or insulin response, an agent for enhancing glucose uptake into a cell, and an agent for inducing differentiation into an adipocyte, characterized in that each comprises as an effective ingredient a processed product derived from at least one plant selected from the group consisting of (a) a plant belonging to Tiliaceae, (b) a plant belonging to Zingiberaceae, (c) a plant belonging to Compositae, (d) a plant belonging to Liliaceae, and (e) a plant belonging to Polygonaceae.

    摘要翻译： 本发明涉及一种伴随胰岛素或胰岛素反应量异常的疾病的治疗剂和预防剂，用于胰岛素模拟作用的药物，用于治疗预防伴随异常的疾病的食品，饮料和饲料 一定量的胰岛素或胰岛素反应，用于增强葡萄糖摄入细胞的药剂和用于诱导分化成脂肪细胞的药剂，其特征在于每种药物包含作为有效成分的来自至少一种选自以下的植物的加工产品： （a）属于尖嘴科的植物，（b）属于姜科的植物，（c）属于菊科的植物，（d）属于百合科的植物，和（e）属于Poly科的植物。