公开(公告)号：US20240148814A1

公开(公告)日：2024-05-09

申请号：US18280505

申请日：2022-03-11

申请人： Manda Fermentation Co., Ltd.

发明人： SHINSUKE KISHIDA ,  KOTARO FUJIOKA ,  HIDETO TORII ,  HUANG CHUN-MING

IPC分类号： A61K36/73 ,  A61K36/23 ,  A61K36/44 ,  A61K36/45 ,  A61K36/60 ,  A61K36/71 ,  A61K36/752 ,  A61K36/87 ,  A61K36/899 ,  A61K36/906

CPC分类号： A61K36/73 ,  A61K36/23 ,  A61K36/44 ,  A61K36/45 ,  A61K36/60 ,  A61K36/71 ,  A61K36/752 ,  A61K36/87 ,  A61K36/899 ,  A61K36/906

摘要： To provide an inhibitor inhibiting a cytokine storm in a living body due to infectious disease. An inhibitor for inhibiting a cytokine storm includes a fermented composition as a main raw material, the fermented composition is obtained by fermentation and aging of a plurality of substances belonging to fruits, citrus fruits, burdock, and carrot belonging to root vegetables, cereals, sesames, seaweeds, and sugars.

公开(公告)号：US20230165925A1

公开(公告)日：2023-06-01

申请号：US17540201

申请日：2021-12-01

申请人： Meyer Health Jiangsu Co., Ltd.

发明人： Hanping SHI ,  Ru JIA

IPC分类号： A61K36/725 ,  A61K47/24 ,  A61K36/00 ,  A61K36/60 ,  A61K47/26 ,  A61K9/00 ,  A61P25/24 ,  A23L33/00 ,  A23L33/105 ,  A23L33/175 ,  A23L33/115 ,  A23L33/125

CPC分类号： A61K36/725 ,  A61K47/24 ,  A61K36/00 ,  A61K36/60 ,  A61K47/26 ,  A61K9/0056 ,  A61P25/24 ,  A23L33/40 ,  A23L33/105 ,  A23L33/175 ,  A23L33/115 ,  A23L33/125 ,  A61K2236/15 ,  A61K2236/333 ,  A61K2236/51 ,  A61K2236/39 ,  A61K2236/37 ,  A61K2236/53 ,  A23V2002/00

摘要： An antidepressant food and a method for preparing the same are provided. The antidepressant food includes, by mass percentage, Semen ziziphi spinosae powder in a range of 28% to 36%, γ-aminobutyric acid in a range of 10% to 15%, theanine in a range of 15% to 20%, phosphatidylserine in a range of 10% to 20%, Ficus tikoua extract in a range of 8% to 14%, Huperzia serrata extract in a range of 10% to 16%, sucralose in a range of 0.5% to 1% and fruit essence in a range of 0.5% to 1.5%.

公开(公告)号：US09610315B2

公开(公告)日：2017-04-04

申请号：US13144413

申请日：2010-01-15

申请人： Salvatore Munafo' ,  Luisa Rizza

发明人： Salvatore Munafo' ,  Luisa Rizza

IPC分类号： A61K9/00 ,  A01N43/16 ,  A61K36/00 ,  A61K9/02 ,  A61K9/48 ,  A61K36/63 ,  A61K47/10 ,  A61K36/33 ,  A61K36/60

CPC分类号： A61K36/60

摘要： Oral pharmaceutical, nutraceutical, health foods and medical device compositions based on polysaccharides from Opuntia Ficus Indica cladodes in combination with other active substances are useful for the prevention or treatment of GERD (Gastro-Esophageal Reflux Disease), gastric esophagitis and related diseases (e.g. dyspepsia, esophagitis, esofageal tumour, gastro-intestinal symptoms, chronic pharyngitis, Barrett's esophagus, esophageal adenocarcinoma, GERD-related pulmonary symptoms).

公开(公告)号：US09370544B2

公开(公告)日：2016-06-21

申请号：US14078053

申请日：2013-11-12

申请人： Unigen, Inc.

发明人： Qi Jia

IPC分类号： A01N65/00 ,  A61K36/539 ,  A61K31/35 ,  A61K36/11 ,  A61K36/15 ,  A61K36/185 ,  A61K36/28 ,  A61K36/47 ,  A61K36/48 ,  A61K36/484 ,  A61K36/486 ,  A61K36/53 ,  A61K36/54 ,  A61K36/60 ,  A61K36/906 ,  A61K36/9062

CPC分类号： A61K36/539 ,  A61K31/35 ,  A61K31/353 ,  A61K31/7048 ,  A61K36/11 ,  A61K36/15 ,  A61K36/185 ,  A61K36/28 ,  A61K36/47 ,  A61K36/48 ,  A61K36/484 ,  A61K36/486 ,  A61K36/53 ,  A61K36/54 ,  A61K36/60 ,  A61K36/74 ,  A61K36/906 ,  A61K36/9062

摘要： The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions mediated by the COX-2 and 5-LO pathways. The present invention further provides a novel method for simultaneously inhibiting the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) enzymes, and reducing cox-2 mRNA production. Finally, the present invention includes a method for weight loss and blood glucose control. The methods of this invention are comprised of administering to a host in need thereof an effective amount of the composition of this invention together with a pharmaceutically acceptable carrier. This invention relates generally to the prevention and treatment of diseases and conditions mediated by the cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LO) pathways, including but not limited to the relief joint discomfort and pain associated with conditions such as osteoarthritis, rheumatoid arthritis, and other injuries that result from overuse.

摘要翻译： 本发明提供由两种特定类别的化合物 - 游离B-环类黄酮和黄烷的混合物组成的新型组合物，用于预防和治疗由COX-2和5-LO介导的疾病和病症 途径。 本发明还提供了同时抑制环氧合酶-2（COX-2）和5-脂氧合酶（5-LO）酶，降低cox-2 mRNA产生的新方法。 最后，本发明包括减肥和血糖控制的方法。 本发明的方法包括向有需要的宿主施用有效量的本发明组合物和药学上可接受的载体。 本发明一般涉及由环氧合酶-2（COX-2）和5-脂氧合酶（5-LO）途径介导的疾病和病症的预防和治疗，包括但不限于与这样的病症有关的救济关节不适和疼痛 作为骨关节炎，类风湿性关节炎以及过度使用引起的其他损伤。

公开(公告)号：US08790724B2

公开(公告)日：2014-07-29

申请号：US13028853

申请日：2011-02-16

申请人： Qi Jia

发明人： Qi Jia

IPC分类号： A61K36/539 ,  A61K36/00

CPC分类号： A61K8/97 ,  A61K8/498 ,  A61K8/67 ,  A61K31/352 ,  A61K31/353 ,  A61K31/7048 ,  A61K36/11 ,  A61K36/15 ,  A61K36/185 ,  A61K36/28 ,  A61K36/47 ,  A61K36/48 ,  A61K36/484 ,  A61K36/486 ,  A61K36/53 ,  A61K36/539 ,  A61K36/54 ,  A61K36/60 ,  A61K36/906 ,  A61K36/9062 ,  A61K45/06 ,  A61K2800/782 ,  A61Q19/00 ,  A61Q19/004 ,  A61Q19/08 ,  A61K2300/00

摘要： The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds—Free-B-Ring flavonoids and flavans—for use in the prevention and treatment of diseases and conditions associated with the skin. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity in normal, aged and damaged dermal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the skin mediated by cyclooxygenase (COX) and lipoxygenase (LOX). The method for preventing and treating COX and LOX mediated diseases and conditions of the skin is comprised of topically administering to a host in need thereof a therapeutically effective amount of a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and/or isolated from a single plant or multiple plants, preferably in the Scutellaria and Acacia genus of plants and pharmaceutically and/or cosmetically acceptable carriers. Finally the present invention provides a method for the prevention and treatment of COX and LOX mediated diseases and conditions, including but not limited to sun burns, thermal burns, acne, topical wounds, minor inflammatory conditions caused by fungal, microbial and viral infections, vitilago, systemic lupus erythromatosus, psoriasis, carcinoma, melanoma, as well as other mammal skin cancers, skin damage resulting from exposure to ultraviolet (UV) radiation, chemicals, heat, wind and dry environments, wrinkles, saggy skin, lines and dark circles around the eyes, dermatitis and other allergy related conditions of the skin. Use of the composition described herein also affords the benefit of smooth and youthful skin with improved elasticity, reduced and delayed aging, enhanced youthful appearance and texture, and increased flexibility, firmness, smoothness and suppleness.

公开(公告)号：US08715750B2

公开(公告)日：2014-05-06

申请号：US14000017

申请日：2012-02-16

申请人： Valeria Lucila Sainz Prestel ,  Adrian Alonso Sainz Gutierrez

发明人： Valeria Lucila Sainz Prestel ,  Adrian Alonso Sainz Gutierrez

IPC分类号： A01N65/00

CPC分类号： A61K36/60 ,  A61K36/00 ,  B29C45/00

摘要： A resin extract from the Ficus pertusa L.f and/or Ficus eximia Schott tree and method of use as an active principle in the production of a pharmacologically active product for the treatment of acute and/or chronic tissue lesions in both bone tissue and soft tissue. A method for obtaining the extract is also disclosed.

摘要翻译： 来自榕属榕树（Ficus pertusa L.f）和/或榕属榕树（Ficus eximia Schott tree）的树脂提取物以及用于生产用于治疗骨组织和软组织中的急性和/或慢性组织损伤的药理活性产物的活性成分的方法。 还公开了获得提取物的方法。

公开(公告)号：US20140088548A1

公开(公告)日：2014-03-27

申请号：US13798984

申请日：2013-03-13

申请人： Satoshi SHINKAWA

发明人： Satoshi SHINKAWA

IPC分类号： A61N5/06

CPC分类号： A61N5/062 ,  A61K31/355 ,  A61K31/575 ,  A61K31/7048 ,  A61K36/062 ,  A61K36/185 ,  A61K36/232 ,  A61K36/48 ,  A61K36/60 ,  A61K2236/19 ,  A61N5/0613 ,  A61N5/0625 ,  A61N5/1028 ,  A61N2005/066

摘要： The present invention provides a set of body slimming compositions, for application to a body before irradiating the body with a far-infrared ray in an atmosphere of 50° C. or thereabout. The slimming composition set includes a first external composition containing a cosmetic base, a Bacillus-fig-soybean fermented liquor, a Bacillus-Monascus-angelica-soybean fermented liquor, a Bacillus-longan-soybean fermented liquor, orizanol, tocopheryl acetate, macadamia nut oil, and glucosyl hesperidine, and a second external composition containing a cosmetic base, a Bacillus-persimmon-soybean fermented liquor, a Waltheria indica leaf extract, and ascorbyl tetrahexyldecanoate. The first external composition is applied to a lymphatic node region of the body, and the second external composition is applied to a slimming target region of the body. The composition set of the invention can activate lymph or lipase, whereby a remarkable body slimming effect can be attained.

摘要翻译： 本发明提供一组身体减肥组合物，用于在50℃或以上的气氛中用远红外线照射身体之前应用于身体。 减肥组合物包括含有化妆品基质，无芽孢杆菌大豆发酵液，芽孢杆菌 - 当归大豆发酵液，芽孢杆菌 - 大豆发酵液，orizanol，生育酚乙酸酯，澳洲坚果坚果的第一外用组合物 油和葡糖基橙皮苷，以及含有化妆品基质，芽孢杆菌 - 大豆发酵液，禾本科植物叶提取物和抗坏血酸四己基癸酸酯的第二外用组合物。 将第一外用组合物施用于身体的淋巴结区域，将第二外用组合物施用于身体的减肥对象区域。 本发明的组合物可以激活淋巴或脂肪酶，从而可以获得显着的身体减肥效果。

公开(公告)号：US20130108567A1

公开(公告)日：2013-05-02

申请号：US13807904

申请日：2011-07-04

申请人： Jin Young Lee ,  Hyung Jun Lim

发明人： Jin Young Lee ,  Hyung Jun Lim

IPC分类号： A61K8/97 ,  A61Q19/02

CPC分类号： A61K8/97 ,  A61K36/60 ,  A61K2800/782 ,  A61Q19/02

摘要： The present invention relates to a skin external composition comprising an extract of the flower and fruit of paper mulberry, and more particularly to a skin external composition containing, as an active ingredient, an extract of flower and fruit of paper mulberry, which shows an excellent skin-whitening effect by effectively inhibiting melanin production.

摘要翻译： 本发明涉及一种皮肤外用组合物，其包含桑叶的花和果实的提取物，更具体地说，涉及含有桑叶花和果实提取物作为活性成分的皮肤外用组合物，其表现出极好的效果 通过有效抑制黑色素生成，增加皮肤美白效果。

公开(公告)号：US20130101689A1

公开(公告)日：2013-04-25

申请号：US13808021

申请日：2011-07-04

申请人： Jin Young Lee ,  Hyang Tae Choi ,  Han Byul Kim ,  Ji Seong Kim

发明人： Jin Young Lee ,  Hyang Tae Choi ,  Han Byul Kim ,  Ji Seong Kim

IPC分类号： A61K36/60

CPC分类号： A61K36/605 ,  A61K8/0212 ,  A61K8/97 ,  A61K36/60 ,  A61K2800/78 ,  A61Q5/00 ,  A61Q5/12 ,  A61Q19/00 ,  A61Q19/008 ,  A61Q19/06 ,  A61Q19/08

摘要： The present invention relates to a composition containing a paper mulberry extract, and more particularly to a composition containing, as an active ingredient, a paper mulberry extract which has effects on enhancement of skin moisturization, inhibition of skin aging, alleviation of inflammation, antibacterial activity, pore size reduction, sebum control, skin complexion improvement, decomposition of subcutaneous fat, stimulation of melanin synthesis, and gray hair prevention.

摘要翻译： 本发明涉及一种含有桑叶提取物的组合物，更具体地说，涉及一种含有桑叶提取物作为活性成分的组合物，其具有增强皮肤保湿作用，抑制皮肤老化，减轻炎症，抗菌活性 ，孔径减少，皮脂控制，皮肤肤色改善，皮下脂肪分解，刺激黑色素合成和防止灰白色毛发。

公开(公告)号：US20090232749A1

公开(公告)日：2009-09-17

申请号：US11720768

申请日：2005-11-24

申请人： Richard Jay Adler

发明人： Richard Jay Adler

IPC分类号： A61K8/97 ,  A61Q11/00 ,  A61P31/04 ,  A61P31/10

CPC分类号： A61K36/80 ,  A61K31/198 ,  A61K36/19 ,  A61K36/21 ,  A61K36/236 ,  A61K36/28 ,  A61K36/39 ,  A61K36/40 ,  A61K36/48 ,  A61K36/53 ,  A61K36/60 ,  A61K36/61 ,  A61K36/70 ,  A61K36/82 ,  A61K36/899 ,  A61K2300/00

摘要： Composition comprising a mixture of radix polygoni multiflori, Fructus Corni, cuscuta japonica, rehmannia glutinosa, licorice, asparagine, Derla andrographis and a composition comprising a mixture of Salvida persica, achyranthes aspera, spilanthes acmela, clove, picus Bengalensis, acacia nilotioca resen, eucalyptus, mint, green tea, bamboo silica for the acute and/or long term treatment of of microbial infections, in particular of oral pathogenic micro-organisms, in particular dental caries, periodontosis, gingivitis, gum disease, gum bleeding and/or plaque reduction.

摘要翻译： 组合物，其包含茯苓多糖，枸杞，c ica，地黄，甘草，天冬酰胺，Derla穿心莲的混合物和包含Salvida persica，achyranthes aspera，spilanthes acmela，丁香，picus Bengalensis，阿拉伯胶，桉树，桉树 ，薄荷，绿茶，竹二氧化硅，用于急性和/或长期治疗微生物感染，特别是口腔致病微生物，特别是龋齿，牙周病，牙龈炎，牙龈疾病，牙龈出血和/或斑块减少 。