公开(公告)号：US06929750B2

公开(公告)日：2005-08-16

申请号：US10467843

申请日：2002-03-11

Applicant: Thomas Laurell ,  Mats Allers ,  Henrik Jönsson ,  Hans W. Persson ,  Andreas Nilsson ,  Filip Tobias Petersson

Inventor： Thomas Laurell ,  Mats Allers ,  Henrik Jönsson ,  Hans W. Persson ,  Andreas Nilsson ,  Filip Tobias Petersson

IPC: A61M1/02 ,  A61M1/34 ,  A61M1/36 ,  B01J19/00 ,  B03B5/00 ,  B03B5/02 ,  B01D43/00 ,  B01J8/16

CPC classification number: A61M1/3472 ,  A61M1/3479 ,  A61M1/3496

Abstract: The present invention provides a device and a method for separating particles from fluids using ultrasound, laminar flow, and stationary wave effects comprising a micro-technology channel system with an integrated branching point or branching fork, and a single ultrasound source. One of the characteristics of the invention is that the single ultrasound source, which generates the standing waves, excites the complete structure including the channel system. No special reflectors or the like are needed. Extremely thin dividers can separate the flow, thereby enhancing the effectiveness of the device. The device could be manufactured in silicon and the ultrasound energy could preferably be delivered by a piezoelectric element.

Abstract translation: 本发明提供一种使用超声，层流和静止波效应从颗粒流体中分离颗粒的装置和方法，其包括具有集成分支点或分支叉的微技术通道系统和单个超声波源。 本发明的特征之一是产生驻波的单个超声波源激发包括通道系统的完整结构。 不需要特殊的反光镜等。 非常薄的分隔器可以分离流动，从而提高装置的有效性。 该器件可以在硅中制造，并且超声能量可以优选地由压电元件传送。

公开(公告)号：US20060052854A1

公开(公告)日：2006-03-09

申请号：US10502574

申请日：2003-02-05

Applicant: Mats Allers ,  Anders Lunderquist ,  Fredrik Boris-Moller ,  Tadeusz Wieloch

Inventor： Mats Allers ,  Anders Lunderquist ,  Fredrik Boris-Moller ,  Tadeusz Wieloch

IPC: A61F7/00 ,  A61F7/12

CPC classification number: A61M1/369 ,  A61M1/1698 ,  A61M2205/3606

Abstract: The present invention relates to a method and equipment for controlling the temperature of the brain or brain hemisphere. More specifically the present invention refers to a method and equipment for quick and efficient control of the temperature of the brain and for maintaining a low temperature in the brain. The inventive concept can be divided into three phases. Firstly, an emergency whole body temperature control phase providing a quick temperature control at for example a scene of accident. Secondly, a brain-selective temperature control phase providing a more efficient temperature control at for example an emergency room and thirdly, a maintained temperature control phase providing an even more efficient temperature control for a selected period of time.

公开(公告)号：US20050209662A1

公开(公告)日：2005-09-22

申请号：US10708624

申请日：2004-03-16

Applicant: Anders Lunderqvist ,  Mats Allers ,  Fredrik Boris-Moller ,  Tadeusz Wielock

Inventor： Anders Lunderqvist ,  Mats Allers ,  Fredrik Boris-Moller ,  Tadeusz Wielock

IPC: A61F7/00 ,  A61F7/12

CPC classification number: A61F7/123 ,  A61F2007/0006 ,  A61F2007/0054 ,  A61F2007/0095

Abstract: A system (10) for cerebral temperature control of a living being, comprising a double lumen catheter means (30) configured to be introduced through a nostril of a living being and to be placed with its tip at the level of the back of the tongue. The double lumen catheter means (30) comprises a first lumen (32) and a second lumen (38), said first and second lumens are in fluid communication by means of a set of end openings (34), said second lumen being configured as an expandable balloon. Further comprising a temperature regulator (24) connected to a reservoir (20) comprising a fluid (22), said temperature regulator being configured to regulate the temperature of said fluid, and means (12, 14, 16) for circulating said temperature regulated fluid from said reservoir into said first lumen, from said first lumen into said second lumen, and from said second lumen back to said reservoir.

Abstract translation: 一种用于对生物进行脑温控制的系统（10），包括双腔导管装置（30），所述双腔导管装置被构造成通过活体的鼻孔引入并且将其尖端放置在舌的背部的水平面上 。 双腔导管装置（30）包括第一腔（32）和第二腔（38），所述第一腔和第二腔与一组端开口（34）流体连通，所述第二腔配置为 一个可膨胀的气球。 还包括连接到包括流体（22）的储存器（20）的温度调节器（24），所述温度调节器被配置为调节所述流体的温度，以及用于使所述温度调节流体循环的装置（12,14,16） 从所述储存器进入所述第一腔，从所述第一腔进入所述第二腔，并从所述第二腔回到所述储存器。

公开(公告)号：US06287273B1

公开(公告)日：2001-09-11

申请号：US09357124

申请日：1999-07-20

Applicant: Mats Allers ,  Krasnodar Ivancev ,  Bengt Jeppson

Inventor： Mats Allers ,  Krasnodar Ivancev ,  Bengt Jeppson

IPC: A61M100

CPC classification number: A61M1/3621 ,  A61M1/3613 ,  A61M1/3615 ,  A61M25/1011 ,  A61M2025/1052 ,  A61M2025/1095 ,  A61M2210/1071

Abstract: A perfusion system for non-surgically isolating and perfusing an organ, particularly the liver (101), in a patient, and including; by-pass cathether apparatus having inlet and outlet lumens (111, 112) introducible into the blood vessels of the organ percutaneously and devised so as to by-pass the blood flow past the organ in a by-pass circuit; perfusion catheter apparatus having inlet and outlet lumens (114, 116) introducible into the blood vessels percutaneously and being devised so as to lead the flow of perfusion fluid in a perfusion circuit through the organ; occlusive seals (106, 108) for isolating the organ from the systemic blood flow; pump apparatus including a by-pass pump (261), a perfusion fluid pump (124) and a suction pump (134) for establishing a negative relative pressure at the perfusion outlet from the organ; and control apparatus (128) coupled to the pumps (124, 126, 134) so as to control the operation thereof such that the outflow of fluid from the organ exceeds the inflow of fluid into the organ in the perfusion circuit due to a net volume contribution of blood from the systemic circulation entering the isolated organ.

Abstract translation: 一种用于在患者中非手术分离和灌注器官，特别是肝脏（101）的灌注系统，并且包括： 具有通过经皮导入到所述器官的血管中的入口和出口腔（111,112）的旁路导管装置，设计成旁路通过所述器官的血流; 灌注导管装置，其具有入口和出口腔（114,116），其可经皮导入血管并设计成引导灌注回路中灌注流体通过所述器官的流动; 闭塞密封件（106,108），用于将器官与全身血流分离; 包括旁路泵（261），灌注流体泵（124）和抽吸泵（134），用于在器官的灌注出口处建立负相对压力; 和耦合到所述泵（124,126,134）的控制装置（128），以便控制其操作，使得来自所述器官的流体的流出超过由于净体积而在所述灌注回路中流体进入所述器官的流入 血液从系统循环中进入分离器官的贡献。

公开(公告)号：US20090221949A1

公开(公告)日：2009-09-03

申请号：US10505349

申请日：2003-02-21

Applicant: Mats Allers ,  Lars Eriksson ,  Lars Holmberg ,  Frank Schanne

Inventor： Mats Allers ,  Lars Eriksson ,  Lars Holmberg ,  Frank Schanne

IPC: A61M1/36 ,  A61M25/00 ,  A61B17/00 ,  A61M25/10 ,  A61M1/00 ,  A61F7/00

CPC classification number: A61M1/3621 ,  A61M1/1698 ,  A61M1/3615 ,  A61M1/3692 ,  A61M25/0032 ,  A61M2025/0031 ,  A61M2027/004

Abstract: An apparatus for circulatory isolation and treatment of a part of a patient's body includes a fluid circulation loop having a first end and a second end, a flow obstructer adapted for obstructing blood flow in a patient's blood vessel such that a body part or organ becomes circulatorily isolated from the circulation of the rest of the body, and a flow-through arrangement including first and second flow-through members respectively connected to the first and second ends of the fluid circulation loop, for providing the isolated part of the patient's body with a fluid connection to the fluid circulation loop, allowing circulation of a therapeutic fluid through the isolated body part.

Abstract translation: 一种用于循环隔离和治疗患者身体的一部分的装置包括具有第一端和第二端的流体循环回路，适于阻塞患者血管中的血液流动的阻流器，使得身体部位或器官变得循环 与身体的其余部分的循环隔离，以及包括分别连接到流体循环回路的第一和第二端的第一和第二流通构件的流通装置，用于向患者身体的隔离部分提供 流体连接到流体循环回路，允许治疗性流体通过分离的身体部分循环。