-
公开(公告)号:US09975136B2
公开(公告)日:2018-05-22
申请号:US14123634
申请日:2012-06-04
CPC分类号: B05B17/0646 , A61M11/005 , A61M15/00 , A61M15/0015 , A61M15/0018 , A61M15/0085
摘要: An aerosol generator for generating an aerosol from a fluid, comprising: a vibratable membrane (22) having a first side (24) for being in contact with the fluid and an opposite second side (25), the membrane having a plurality of through holes (26) penetrating the membrane in an extension direction (E) from the first side to the second side, whereby the fluid passes the through holes from the first side to the second side when the membrane is vibrated for generating the aerosol at the second side, each through hole (26) having along its extension direction (E) a smallest diameter (Ds), a larger diameter (DL) that is larger than the smallest diameter and defined by that diameter that is closest to triple, preferably twice said smallest diameter, each through hole having a nozzle portion (32) defined by that continuous portion of the through hole in the extension direction comprising the smallest diameter of the through hole and bordered by the larger diameter of the through hole, characterized in that the ratio of the total length of each through hole (26) in the extension direction to the length of a respective one of said nozzle portions (32) in the extension direction is at least (4), preferably at least (4.5) and most preferred equal to or larger than (5).
-
公开(公告)号:US20140318304A1
公开(公告)日:2014-10-30
申请号:US14349813
申请日:2012-08-16
申请人: Michael Hahn , Martin Fleischer
发明人: Michael Hahn , Martin Fleischer
IPC分类号: B62D1/184
CPC分类号: B62D1/184 , F16H25/186
摘要: An assembly includes a first cam carrier and at least one other cam carrier for a securing device for an adjustable steering column of a motor vehicle. Each of the cam carriers has at least one cam, and the carriers are located opposite one another so that they can rotate against one another about a rotational axis. When the first cam carrier rotates against the other cam carrier through a rotational angle about the rotational axis, the cam of the first cam carrier rests on and glides along the cam of the other cam carrier on a contact path. The contact path runs at a radial distance from the rotational axis, and the distance altering depends on the rotational angle.
摘要翻译: 组件包括第一凸轮架和用于机动车辆的可调转向柱的固定装置的至少一个其它凸轮架。 每个凸轮支架具有至少一个凸轮,并且托架彼此相对地定位,使得它们可以围绕旋转轴线彼此相对旋转。 当第一凸轮架相对于另一个凸轮架旋转一个围绕旋转轴线的转角时,第一凸轮架的凸轮在接触路径上靠着另一个凸轮架的凸轮滑动并滑动。 接触路径在距离旋转轴线的径向距离处延伸,并且距离改变取决于旋转角度。
-
公开(公告)号:US08796335B2
公开(公告)日:2014-08-05
申请号:US13431934
申请日:2012-03-27
申请人: Michael Hahn , Thomas Lampe , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Volkhart Min-Jian Li , Eva-Maria Becker , Friederike Stoll , Andreas Knorr , Elisabeth Woltering
发明人: Michael Hahn , Thomas Lampe , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Volkhart Min-Jian Li , Eva-Maria Becker , Friederike Stoll , Andreas Knorr , Elisabeth Woltering
IPC分类号: A01N37/12 , A01N37/44 , A61K31/195 , C07C45/00
CPC分类号: C07C231/14 , A61K9/0053 , A61K31/196 , A61K45/06 , C07C233/55 , C07C235/38 , C07C2601/02 , C07C2601/04 , C07C2601/08
摘要: The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
-
公开(公告)号:US20140193342A1
公开(公告)日:2014-07-10
申请号:US14125273
申请日:2012-06-11
CPC分类号: A61K49/128 , A61K31/00 , A61K47/585 , A61K47/65 , A61K49/0041 , A61K49/0043 , A61K49/0054 , A61K49/0082 , A61K49/1809
摘要: Provided herein is a method for enzymatically triggered assembly of polymeric nanostructures for detection of cancer-associated enzymes in vivo. By detecting enzymatic signals associated with disease, one can sensitively determine the site, and extent of disease within a patient.
摘要翻译: 本文提供了一种用于在体内检测癌症相关酶的聚合纳米结构的酶促触发装配的方法。 通过检测与疾病相关的酶信号,可以敏感地确定患者内的部位和疾病程度。
-
公开(公告)号:US20130079412A1
公开(公告)日:2013-03-28
申请号:US13431934
申请日:2012-03-27
申请人: Michael HAHN , Thomas LAMPE , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Volkhart Min-Jian LI , Eva-Maria BECKER , Friederike STOLL , Andreas KNORR , Elisabeth WOLTERING
发明人: Michael HAHN , Thomas LAMPE , Johannes-Peter STASCH , Karl-Heinz SCHLEMMER , Frank WUNDER , Volkhart Min-Jian LI , Eva-Maria BECKER , Friederike STOLL , Andreas KNORR , Elisabeth WOLTERING
IPC分类号: C07C233/55 , A61K45/06 , A61K31/196
CPC分类号: C07C231/14 , A61K9/0053 , A61K31/196 , A61K45/06 , C07C233/55 , C07C235/38 , C07C2601/02 , C07C2601/04 , C07C2601/08
摘要: The present application relates to novel 3-phenylpropionic acid derivatives which carry a branched or cyclic alkyl substituent in the 3-position, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
摘要翻译: 本申请涉及在3-位上带有支链或环状烷基取代基的新型3-苯基丙酸衍生物,其制备方法,其用于治疗和/或预防疾病及其用于制备药物的用途 用于治疗和/或预防疾病,特别是用于治疗和/或预防心血管疾病。
-
公开(公告)号:US20100221061A1
公开(公告)日:2010-09-02
申请号:US12295327
申请日:2007-05-08
申请人: Michael Hahn , Thomas Herrmann
发明人: Michael Hahn , Thomas Herrmann
IPC分类号: F16J15/52
CPC分类号: B62D3/12 , B62D7/163 , F16C11/0623 , F16C35/02 , F16C2326/24 , Y10T74/1967 , Y10T403/315 , Y10T403/32631 , Y10T403/32729
摘要: A joint arrangement, for a vehicle, is provided with a joint (7), which has a joint housing (8) and a pivot pin (9) mounted movably in relation thereto. The arrangement also includes a rod (4), which has a cavity (6) and is connected to the joint (7); a sealing bellows (10), which defines an interior space (10) and in which the joint (7) is arranged at least partially; and a gas-permeable connection (13), which connects the cavity (6) of the rod (4) to the interior space (11) of the sealing bellows (10) and has at least one groove (15), which is formed in a front side (21) of the joint (7), which said front side faces the rod (4), opens into the interior space (11) and has a radially outer end (27). The groove (15) with its radially outer end ends at a spaced location from the outer circumferential contour of the front surface (21).
摘要翻译: 一种用于车辆的联合装置设置有具有联接壳体(8)和可相对于其移动地安装的枢轴销(9)的接头(7)。 该装置还包括具有空腔(6)并连接到接头(7)的杆(4); 密封波纹管(10),其限定内部空间(10),并且所述接头(7)至少部分地布置在所述密封波纹管中; 以及将所述杆(4)的空腔(6)连接到所述密封波纹管(10)的内部空间(11)并且具有至少一个凹槽(15)的透气连接件(13) 在所述前侧面向所述杆(4)的所述接头(7)的前侧(21)中,通向所述内部空间(11)并且具有径向外端(27)。 槽(15)的径向外端在与前表面(21)的外周轮廓相隔的位置处终止。
-
公开(公告)号:US20100168240A1
公开(公告)日:2010-07-01
申请号:US12529713
申请日:2008-03-15
申请人: Michael Hahn , Eva-Maria Becker , Andreas Knorr , Dirk Schneider , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Dieter Lang
发明人: Michael Hahn , Eva-Maria Becker , Andreas Knorr , Dirk Schneider , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Dieter Lang
IPC分类号: A61K31/194 , C07C65/28 , A61P9/04 , A61P9/12 , A61P9/10
CPC分类号: C07C65/28
摘要: The invention relates to novel substituted dibenzoic acid derivatives of formula (I), wherein A represents a group of formula (II) or (III), to methods for producing the same, and to their use in the treatment and/or prophylaxis of diseases. The invention also relates to the use of said substances in the production of drugs for the treatment and/or prophylaxis of diseases, especially in the treatment and/or prevention of cardiovascular diseases.
摘要翻译: 本发明涉及式(I)的新型取代二苯甲酸衍生物,其中A代表式(II)或(III)的基团,其制备方法及其在治疗和/或预防疾病中的用途 。 本发明还涉及所述物质在制备药物中用于治疗和/或预防疾病的用途,特别是用于治疗和/或预防心血管疾病。
-
公开(公告)号:US07716651B2
公开(公告)日:2010-05-11
申请号:US11044354
申请日:2005-01-26
申请人: Ryan Edward Cukierman , Christopher Michael Hahn , Vikram Madan , Ravipal Soin , Kamesh Chander Tumsi Dayakar
发明人: Ryan Edward Cukierman , Christopher Michael Hahn , Vikram Madan , Ravipal Soin , Kamesh Chander Tumsi Dayakar
IPC分类号: G06F9/44 , G06F15/16 , G06F15/173
CPC分类号: G06F9/542 , G06F9/4451 , G06F2209/543
摘要: An improved system and method for a context-awareness platform that may be used to adapt an execution environment is provided. A framework with interfaces for setting, tracking, and getting context information about the execution environment of a computer system includes a context engine and a unified data store for aggregating context information at a platform level for access by executables running on the platform. The context engine may receive requests to perform context information operations from executables such as setting, tracking and getting context information in the data store. Upon receiving a notification of a change in context information, one or more executables may change the execution environment such as reconfiguring system settings. In this way, an executable may adapt its execution environment using context information.
摘要翻译: 提供了一种用于适应执行环境的上下文感知平台的改进的系统和方法。 具有用于设置,跟踪和获得关于计算机系统的执行环境的上下文信息的接口的接口的框架包括上下文引擎和用于在平台级别聚合上下文信息的统一数据存储,用于由在该平台上运行的可执行文件的访问。 上下文引擎可以接收从可执行程序执行上下文信息操作的请求,例如在数据存储中设置,跟踪和获取上下文信息。 在接收到上下文信息改变的通知之后,一个或多个可执行程序可以改变执行环境,例如重新配置系统设置。 以这种方式,可执行程序可以使用上下文信息调整其执行环境。
-
公开(公告)号:US20090291993A1
公开(公告)日:2009-11-26
申请号:US12083509
申请日:2006-10-09
申请人: Stephan Bartel , Michael Hahn , Wahed Ahmed Moradi , Eva-Maria Becker , Thomas Rölle , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Andreas Knorr
发明人: Stephan Bartel , Michael Hahn , Wahed Ahmed Moradi , Eva-Maria Becker , Thomas Rölle , Johannes-Peter Stasch , Karl-Heinz Schlemmer , Frank Wunder , Andreas Knorr
IPC分类号: A61K31/41 , A61K31/195 , A61K31/19 , C07D257/04 , C07C229/00 , C07C59/00
CPC分类号: C07C59/68 , C07C229/14 , C07D249/12 , C07D257/04 , C07D271/07 , C07D271/113
摘要: The present application relates to novel difluorophenol derivatives, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
摘要翻译: 本申请涉及新型二氟苯酚衍生物,其制备方法,其用于治疗和/或预防疾病的用途及其用于治疗和/或预防疾病,特别是用于治疗和/或预防的药物的用途 的心血管疾病。
-
公开(公告)号:US07408357B2
公开(公告)日:2008-08-05
申请号:US10573818
申请日:2004-09-17
申请人: Bernd Adam , Michael Hahn
发明人: Bernd Adam , Michael Hahn
IPC分类号: G01R31/327 , G01N27/00
CPC分类号: H01H1/0015 , H01H9/50 , H01H33/26 , H01H2001/0026
摘要: A device for detecting wear of switching contacts in an electric switch appliance is disclosed, the wear of the contacts being caused at least at a pair of switching contacts appliance. The device includes a lightwave guide and a detector. A light exiting from at least one light source is capable of being injected into the lightwave guide and guided by the lightwave guide up to the detector. The lightwave guide is arranged relative to the pair(s) of switching contacts, such that the intensity of the light injected in the lightwave guide, which is measured by the detector, decreases in the switching appliance as the number of wear particles of contacts generated by the wear of the contacts increases.
摘要翻译: 公开了一种用于检测电开关器具中的开关触点的磨损的装置,至少在一对开关触头装置处引起触点的磨损。 该装置包括光波导和检测器。 从至少一个光源射出的光能够被注入光波导并被光波导引导到检测器。 光波导相对于一对或多个开关触点布置,使得由开关装置测量的在光波导中注入的光的强度在开关器具中随着产生的触点的磨损粒子的数量而减小 通过接触的磨损增加。
-
-
-
-
-
-
-
-
-