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1.发明授权Wicking cassette method and apparatus for automated rapid immunohistochemistry 有权用于自动快速免疫组化的芯吸盒方法和装置公开(公告)号：US07838283B2
公开(公告)日：2010-11-23
申请号：US11912095
申请日：2006-04-21
IPC分类号： C12M1/34
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve automatic withdrawal of a substance at the end of appropriate processing sequences such as histochemical processing may involve a plurality of samples for which substances removed by moving a wicking cartridge that may have sequentially advanced absorbsant material on rolls that are advanced an appropriate amount based upon usage in sequences such as repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Snap in wicking cassettes and perhaps antibody and other substances may be included to ease operator actions and to permit location specific substance applications perhaps by including single container multiple chamber multiple fluidic substance magazines, linearly disposed multiple substance source, and primary antibody cartridges.
摘要翻译： 可以被配置为在诸如组织化学处理的适当处理顺序结束时实现物质的自动抽出的样品处理系统可以包括多个样品，通过移动可以在辊上具有顺序的先进吸收材料的芯吸筒去除物质 其基于诸如重复消除和重新应用流体物质的顺序进行适当的量，可能通过毛细血管运动的作用，以便刷新与诸如活组织检查或其它样品的样品相邻的微环境。 可以包括吸入芯片，也可能包含抗体和其他物质，以减轻操作者的行为，并允许通过包括单容器多腔多重流体物质杂志，线性放置的多物质源和一级抗体盒来允许位置特异性物质应用。
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2.发明申请Parallel Processing Fluidic Method and Apparatus for Automated Rapid Immunohistochemistry 有权用于自动快速免疫组化的平行加工流体方法和装置公开(公告)号：US20080213804A1
公开(公告)日：2008-09-04
申请号：US11912273
申请日：2006-04-21
IPC分类号： G01N33/574 , G01N33/53
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve parallel or coincidental sample processing such as histochemical processing may involve a plurality of samples arranged for coincidental movement perhaps by use of angular microscopic slide movements to cause processing activity that may include repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Snap in antibody and other substances may be included to ease operator actions and to permit location specific substance applications perhaps by including single container multiple chamber multiple fluidic substance magazines, linearly disposed multiple substance source, and primary antibody cartridges. Through refreshing of a microenvironment, depletion of the microenvironment is avoided and the time necessary for slide processing may be dramatically shortened from a more common 60 to 120 minutes to perhaps less than 15 minutes so as to permit use of such a system in an intraoperative or surgical environment such as recommended by the College of American Pathologists intraoperative guidelines or the like. Patients may thus avoid a need to be subjected to an additional surgical procedure when lab results become available to see if tumors or the like were fully removed in a prior procedure.
摘要翻译： 可以被配置为实现平行或重复的样品处理（例如组织化学处理）的样品处理系统可以涉及可以通过使用角度显微镜幻灯片移动来布置为巧合运动的多个样品，以引起处理活动，所述处理活动可以包括反复消除和重新应用 流体物质可能通过毛细管运动的作用，以便刷新邻近样品的微环境，例如活组织检查或其它这样的样品。 可以包括抗体和其他物质，以减轻操作者的行为，并允许通过包括单容器多腔多重流体物质杂志，线性放置的多物质源和一级抗体盒来允许位置特异性物质应用。 通过刷新微环境，避免了微环境的消耗，并且幻灯片处理所需的时间可能会从更常见的60到120分钟到可能少于15分钟急剧缩短，以便允许在术中或术中使用这样的系统 手术环境如美国病理学家推荐的术中指南等。 因此，当实验室结果变得可用时，患者可能避免需要进行额外的外科手术，以便在先前的手术中是否完全移除肿瘤等。
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公开(公告)号：US08178350B2
公开(公告)日：2012-05-15
申请号：US11911801
申请日：2006-04-21
申请人： Page A. Erickson , Michael R. Everman , Michael S. Bell , Kevin S. Edberg , Brian D. Sawatzky , Matthew M. Botke
发明人： Page A. Erickson , Michael R. Everman , Michael S. Bell , Kevin S. Edberg , Brian D. Sawatzky , Matthew M. Botke
IPC分类号： G01N35/00
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A method of biochemical processing may, in certain embodiments, involve the steps of use of a consumable biochemical process element and a consumable biochemical process alterable information memory element associated therewith, such as a substance withdrawal consumable biochemical process alterable information memory element, that may be queried and at least some of whose information may be changed as a result of actions conducted during processing of a biochemical test sequence. Accordingly, advantages relative to knowing how much of a consumable biochemical process element has been used, and how much may be available during a biochemical test sequence, may be achieved.
摘要翻译： 在某些实施方案中，生物化学处理的方法可以包括使用消耗性生物化学过程元件和与其相关联的消耗性生物化学过程可变信息存储元件的步骤，例如物质提取消耗性生物化学过程可变信息存储元件，其可以是 查询，并且至少其中一些信息可能由于在生化测试序列的处理期间进行的动作而改变。 因此，可以实现相对于知道消耗性生物化学过程元素已经被使用多少的优点，以及在生物化学测试序列期间可获得多少的优点。
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公开(公告)号：US4561578A
公开(公告)日：1985-12-31
申请号：US661664
申请日：1984-10-17
申请人： Michael S. Bell
发明人： Michael S. Bell
CPC分类号： A45F3/08
摘要： A backpack with a frame to carry a load. The frame has a pair of upright rails, one at each side of the hiker. An encircling belt is attached to each of the upright rails, and a pair of shoulder rests fit over each of the shoulders. Front and rear risers connect to the front and rear legs of the shoulder rests. The rear risers rise from the back of the belt, and the front risers connect to the upright rails. Balance rods extend forwardly from the frame and are vertically pivotable. They can lift and lower the shoulder rests. Forward load-attachment devices on the balance rods can carry a forwardly mounted load.
摘要翻译： 带有框架的背包承载负载。 框架有一对直立导轨，一个在徒步旅行者的每一侧。 每个直立导轨上安装有一个环绕带，一对肩部安置在每个肩部上。 前后立管连接到肩托的前后腿。 后立管从皮带后部上升，前立管连接到直立导轨。 平衡杆从框架向前延伸并且可垂直枢转。 他们可以抬起和降下肩膀。 平衡杆上的正向负载连接装置可承载向前的负载。
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5.发明授权Parallel processing fluidic method and apparatus for automated rapid immunohistochemistry 有权用于自动化快速免疫组织化学的并行处理流体学方法和装置公开(公告)号：US08034610B2
公开(公告)日：2011-10-11
申请号：US11912273
申请日：2006-04-21
IPC分类号： C12M3/00
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve parallel or coincidental sample processing such as histochemical processing may involve a plurality of samples arranged for coincidental movement perhaps by use of angular microscopic slide movements to cause processing activity that may include repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Snap in antibody and other substances may be included to ease operator actions and to permit location specific substance applications perhaps by including single container multiple chamber multiple fluidic substance magazines, linearly disposed multiple substance source, and primary antibody cartridges. Through refreshing of a microenvironment, depletion of the microenvironment is avoided and the time necessary for slide processing may be dramatically shortened.
摘要翻译： 可以被配置为实现平行或重复的样品处理（例如组织化学处理）的样品处理系统可以涉及可以通过使用角度显微镜幻灯片移动来布置为巧合运动的多个样品，以引起处理活动，所述处理活动可以包括反复消除和重新应用 流体物质可能通过毛细管运动的作用，以便刷新邻近样品的微环境，例如活组织检查或其它这样的样品。 可以包括抗体和其他物质，以减轻操作者的行为，并允许通过包括单容器多腔多重流体物质杂志，线性放置的多物质源和一级抗体盒来允许位置特异性物质应用。 通过刷新微环境，避免了微环境的消耗，并且可以显着缩短滑动处理所需的时间。
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公开(公告)号：US20080194034A1
公开(公告)日：2008-08-14
申请号：US11911801
申请日：2006-04-21
申请人： Page A. Erickson , Michael R. Everman , Michael S. Bell , Kevin S. Edberg , Matthew M. Botke , Brian D. Sawatzky
发明人： Page A. Erickson , Michael R. Everman , Michael S. Bell , Kevin S. Edberg , Matthew M. Botke , Brian D. Sawatzky
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve parallel or coincidental sample processing such as histochemical processing may involve a plurality of samples arranged for coincidental movement perhaps by use of angular microscopic slide movements to cause processing activity that may include repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Snap in antibody and other substances may be included to ease operator actions and to permit location specific substance applications perhaps by including single container multiple chamber multiple fluidic substance magazines, linearly disposed multiple substance source, and primary antibody cartridges. Through refreshing of a microenvironment, depletion of the microenvironment is avoided and the time necessary for slide processing may be dramatically shortened from a more common 60 to 120 minutes to perhaps less than 15 minutes so as to permit use of such a system in an intraoperative or surgical environment such as recommended by the College of American Pathologists intraoperative guidelines or the like. Patients may thus avoid a need to be subjected to an additional surgical procedure when lab results become available to see if tumors or the like were fully removed in a prior procedure.
摘要翻译： 可以被配置为实现平行或重复的样品处理（例如组织化学处理）的样品处理系统可以涉及可以通过使用角度显微镜幻灯片移动来布置为巧合运动的多个样品，以引起处理活动，所述处理活动可以包括反复消除和重新应用 流体物质可能通过毛细管运动的作用，以便刷新邻近样品的微环境，例如活组织检查或其它这样的样品。 可以包括抗体和其他物质，以减轻操作者的行为，并允许通过包括单容器多腔多重流体物质杂志，线性放置的多物质源和一级抗体盒来允许位置特异性物质应用。 通过刷新微环境，避免了微环境的消耗，并且幻灯片处理所需的时间可能会从更常见的60到120分钟到可能少于15分钟急剧缩短，以便允许在术中或术中使用这样的系统 手术环境如美国病理学家推荐的术中指南等。 因此，当实验室结果变得可用时，患者可能避免需要进行额外的外科手术，以便在先前的手术中是否完全移除肿瘤等。
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公开(公告)号：US4892240A
公开(公告)日：1990-01-09
申请号：US47807
申请日：1987-05-08
申请人： Michael S. Bell
发明人： Michael S. Bell
IPC分类号： A45F3/08
CPC分类号： A45F3/08
摘要： An exoskeletal carriage for articles to be carried by a person. It includes a belt for supporting the carriage. A front and rear blade-like columnar member is attached to the belt. The columnar members include a channel shape along at least a part of their vertical dimension to give columnar support with minimal bending. Articles to be carried can be attached to the columnar members.
摘要翻译： 用于由人携带的物品的外骨骼运输。 它包括一个用于支撑滑架的皮带。 前后叶片状柱状构件附接到带上。 柱状构件沿其垂直尺寸的至少一部分包括通道形状，以最小的弯曲得到柱状支撑。 要携带的物品可以附在柱状物上。
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8.发明授权Enhanced fluidic method and apparatus for automated rapid immunohistochemistry 有权用于自动化快速免疫组化的增强流体学方法和装置公开(公告)号：US08058010B2
公开(公告)日：2011-11-15
申请号：US11911946
申请日：2006-04-21
IPC分类号： G01N33/53
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve rapid sample processing such as rapid histochemical processing may involve a wave element that can use angular microscopic slide movements to cause repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Through such refreshing of a microenvironment, depletion of the microenvironment is avoided and the time necessary for slide processing may be dramatically shortened.
摘要翻译： 可以被配置为实现快速样品处理（例如快速组织化学处理）的样品处理系统可以涉及可以使用角度微观滑动运动引起重复消除和重新应用流体物质的波浪元件，这可能是通过毛细管运动的作用，以便 刷新与诸如活组织检查或其他样品的样品相邻的微环境。 通过微环境的清新，避免了微环境的消耗，并且可以显着缩短滑动处理所需的时间。
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9.发明申请Enhanced Fluidic Method and Apparatus for Automated Rapid Immunohistochemistry 有权用于自动快速免疫组织化学的增强流体学方法和装置公开(公告)号：US20090004691A1
公开(公告)日：2009-01-01
申请号：US11911946
申请日：2006-04-21
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve rapid sample processing such as rapid histochemical processing may involve a wave element that can use angular microscopic slide movements to cause repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Through such refreshing of a microenvironment, depletion of the microenvironment is avoided and the time necessary for slide processing may be dramatically shortened from a more common 60 to 120 minute to perhaps less than 15 minutes so as to permit use of such a system in an intraoperative or surgical environment such as recommended by the College of American Pathologists intraoperative guidelines or the like. Patients may thus avoid a need to be subjected to an additional surgical procedure when lab results become available to see if tumors or the like were fully removed in a prior procedure.
摘要翻译： 可以被配置为实现快速样品处理（例如快速组织化学处理）的样品处理系统可以涉及可以使用角度微观滑动运动引起重复消除和重新应用流体物质的波浪元件，这可能是通过毛细管运动的作用，以便 刷新与诸如活组织检查或其他样品的样品相邻的微环境。 通过微环境的清新，避免了微环境的消耗，并且幻灯片处理所需的时间可以从更常见的60到120分钟到可能小于15分钟被显着地缩短，以便允许在术中使用这样的系统 或手术环境，例如美国病理学家学院术中指南等推荐的。 因此，当实验室结果变得可用时，患者可能避免需要进行额外的外科手术，以便在先前的手术中是否完全移除肿瘤等。
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10.发明申请Wicking Cassette Method and Apparatus for Automated Rapid Immunohistochemistry 有权用于自动快速免疫组化的芯吸盒方法和装置公开(公告)号：US20080286753A1
公开(公告)日：2008-11-20
申请号：US11912095
申请日：2006-04-21
CPC分类号： G01N35/00029 , G01N1/312 , G01N35/00009 , G01N2035/00039 , Y10T436/11 , Y10T436/112499 , Y10T436/113332
摘要： A sample processing system that may be configured to achieve automatic withdrawal of a substance at the end of appropriate processing sequences such as histochemical processing may involve a plurality of samples for which substances removed by moving a wicking cartridge that may have sequentially advanced absorbsant material on rolls that are advanced an appropriate amount based upon usage in sequences such as repeated elimination and reapplication of a fluidic substance perhaps through the action of capillary motion in order to refresh a microenvironment adjacent to a sample such as a biopsy or other such sample. Snap in wicking cassettes and perhaps antibody and other substances may be included to ease operator actions and to permit location specific substance applications perhaps by including single container multiple chamber multiple fluidic substance magazines, linearly disposed multiple substance source, and primary antibody cartridges.
摘要翻译： 可以被配置为在诸如组织化学处理的适当处理顺序结束时实现物质的自动抽出的样品处理系统可以包括多个样品，通过移动可以在辊上具有顺序的先进吸收材料的芯吸筒去除物质 其基于诸如重复消除和重新应用流体物质的顺序进行适当的量，可能通过毛细血管运动的作用，以便刷新与诸如活组织检查或其它样品的样品相邻的微环境。 可以包括吸入芯片，也可能包含抗体和其他物质，以减轻操作者的行为，并允许通过包括单容器多腔多重流体物质杂志，线性放置的多物质源和一级抗体盒来允许位置特异性物质应用。
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