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公开(公告)号：US20070299238A1
公开(公告)日：2007-12-27
申请号：US11897176
申请日：2007-08-28
IPC分类号： C08G69/08
CPC分类号： C12N5/0068 , A61K9/1676 , A61K47/593 , A61K47/60 , C08G63/664 , C08L71/02 , C12N2533/40 , C08L2666/18
摘要： The invention relates to a block copolymer containing: a) hydrophobic biodegradable polymer; b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b). The invention relates to shaped bodies consisting of the block copolymer and to their utilization, particularly as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
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公开(公告)号：US20070299240A1
公开(公告)日：2007-12-27
申请号：US11897145
申请日：2007-08-28
IPC分类号： C08G63/06
CPC分类号： C12N5/0068 , A61K9/1676 , A61K47/593 , A61K47/60 , C08G63/664 , C08L71/02 , C12N2533/40 , C08L2666/18
摘要： The invention relates to a block copolymer containing: a) hydrophobic biodegradable polymer; b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b). The invention relates to shaped bodies consisting of the block copolymer and to their utilization, particularly as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
摘要翻译： 本发明涉及含有：a）疏水性生物可降解聚合物的嵌段共聚物; b）亲水性聚合物和c）至少一个用于表面改性物质d）与亲水性聚合物b）共价结合的反应性基团。 本发明涉及由嵌段共聚物组成的成型体及其利用，特别是作为组织培养和活性物质的载体，以及活性物质的控制释放和靶向施用。
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公开(公告)号：US20070299227A1
公开(公告)日：2007-12-27
申请号：US11897175
申请日：2007-08-28
CPC分类号： C12N5/0068 , A61K9/1676 , A61K47/593 , A61K47/60 , C08G63/664 , C08L71/02 , C12N2533/40 , C08L2666/18
摘要： The invention relates to a block copolymer containing: a) hydrophobic biodegradable polymer; b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b). The invention relates to shaped bodies consisting of the block copolymer and to their utilization, particularly as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
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公开(公告)号：US20060246041A1
公开(公告)日：2006-11-02
申请号：US11396946
申请日：2006-04-03
申请人： Karin Lauer , Kurt Lang , Apollon Papadimitriou , Ulrike Reiff , Michaela Schulz , Torsten Blunk , Achim Goepferich
发明人： Karin Lauer , Kurt Lang , Apollon Papadimitriou , Ulrike Reiff , Michaela Schulz , Torsten Blunk , Achim Goepferich
CPC分类号： A61L27/3852 , A61L27/3612 , A61L27/3654 , A61L27/3843 , A61L2430/06
摘要： The present invention makes available an optimal concentration of a hedgehog polypeptide for modulating growth and/or cartilage production by chondrocytes. The present invention allows for improvements in the culturing of chondrocytes to develop cartilaginous tissue ex vivo suitable for implantation to replace damaged or deteriorated cartilage in a patient.
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公开(公告)号：US09801977B2
公开(公告)日：2017-10-31
申请号：US14354545
申请日：2012-10-29
申请人： Vuk Savkovic , Christina Dieckmann , Jan-Christoph Simon , Michaela Schulz-Siegmund , Michael Hacker
发明人： Vuk Savkovic , Christina Dieckmann , Jan-Christoph Simon , Michaela Schulz-Siegmund , Michael Hacker
CPC分类号： A61L27/3834 , A61L27/3895 , A61L27/60 , C12N5/0626 , C12N2500/02 , C12N2500/38 , C12N2501/33 , C12N2501/81 , C12N2506/03 , C12N2533/40
摘要： The present invention relates to the field of biology and medicine, and more specifically, to the field of stem-cell biology, involving producing or generating melanocytes from stem-cells and precursors derived from human hair root. Additionally, the present invention relates to the materials and method for producing autografts, homografts or allografts comprising melanocytes in general, as well as the materials and methods for producing autografts, homografts and allografts comprising melanocytes for the treatment of diseases related to depigmentation of the skin and for the treatment of scars.
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公开(公告)号：US20090291106A1
公开(公告)日：2009-11-26
申请号：US12505449
申请日：2009-07-17
CPC分类号： C12N5/0068 , A61K9/1676 , A61K47/593 , A61K47/60 , C08G63/664 , C08L71/02 , C12N2533/40 , C08L2666/18
摘要： A block copolymer containing a) a hydrophobic biodegradable polymer, b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b) is disclosed. Shaped bodies are formed to consist of the block copolymer and are utilized as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
摘要翻译： 含有a）疏水性生物可降解聚合物的嵌段共聚物，b）亲水性聚合物和c）至少一种用于表面改性物质d）与亲水性聚合物b）共价结合的反应性基团。 成型体形成为由嵌段共聚物组成，并用作组织培养和活性物质的载体并用于活性物质的控制释放和靶向施用。
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