公开(公告)号：US4017183A

公开(公告)日：1977-04-12

申请号：US550913

申请日：1975-02-19

Applicant: Werner Lenz ,  Josef Woellhaf ,  Klaus Spreng ,  Manfred Zuerger ,  Paul Hecke ,  Gerhard Hoffmann ,  Milan Obradovic

Inventor： Werner Lenz ,  Josef Woellhaf ,  Klaus Spreng ,  Manfred Zuerger ,  Paul Hecke ,  Gerhard Hoffmann ,  Milan Obradovic

IPC: G03C1/74 ,  B29C31/04 ,  B29C31/06 ,  B29C33/26 ,  B29C35/08 ,  B29C43/10 ,  B29C43/18 ,  B29C43/34 ,  B29C70/78 ,  G03F7/16 ,  G03F7/20 ,  G03F7/26 ,  G03B27/04

CPC classification number: G03F7/16 ,  B29C31/041 ,  B29C33/26 ,  B29C35/0888 ,  B29C43/10 ,  B29C43/18 ,  B29C43/34 ,  B29C70/78 ,  B29C2035/0833 ,  B29C31/06 ,  B29K2105/0002 ,  B29K2909/08 ,  B29L2031/767

Abstract: A process and apparatus for the production of exposed printing plates consisting of a resin layer and a support, said resin layer being prepared from a fluid photopolymerizable material which is introduced into a mold having at least one transparent wall which is covered with an image-bearing transparency, and being exposed through said image-bearing transparency, which causes photopolymerization of the exposed areas of the resin layer and bonds these areas to the support which is provided with an adhesive layer. The improved process comprises introducing a predetermined amount of fluid photopolymerizable material, said amount corresponding substantially to the volume of the resin layer of the exposed printing plate; adjusting said support and said transparent wall of the mold so that they are equidistant from one another, adjustment being advantageously effected by bending or doming the support relative to the transparent wall after the latter has been bent or domed by the fluid material introduced into the mold under pressure. Further embodiments of the invention serve to minimize the loss of photopolymerizable material and to avoid the formation of foam when the fluid material is introduced into the mold. The apparatus of the invention can be manufactured and operated easily and economically.

Abstract translation: 一种用于生产由树脂层和支撑体组成的露出印刷板的方法和装置，所述树脂层由流体可光聚合材料制备，该材料被引入具有至少一个透明壁的模具中，该透明壁被图像承载 透明性，并且通过所述图像承载透明体曝光，这导致树脂层的暴露区域的光聚合并将这些区域粘合到设置有粘合剂层的支撑体上。 改进的方法包括引入预定量的流动可光聚合材料，所述量基本上对应于暴露的印版的树脂层的体积; 调节模具的所述支撑件和所述透明壁使得它们彼此等距离地进行调整，有利地通过在支撑件被引入模具中的流体材料弯曲或穹顶之后相对于透明壁弯曲或拱起支撑件来实现调节 在压力之下。 本发明的其它实施方案用于使可光聚合材料的损失最小化，并且当流体材料被引入模具时避免形成泡沫。 本发明的装置可以容易且经济地制造和操作。

公开(公告)号：US09381356B2

公开(公告)日：2016-07-05

申请号：US14117149

申请日：2012-05-11

Applicant: John Louis Parker ,  James Hamilton Laird ,  Dean Michael Karantonis ,  Milan Obradovic ,  Robert Bruce Gorman

Inventor： John Louis Parker ,  James Hamilton Laird ,  Dean Michael Karantonis ,  Milan Obradovic ,  Robert Bruce Gorman

IPC: A61N1/00 ,  A61N1/36 ,  A61B5/04 ,  A61B5/00 ,  A61N1/05

CPC classification number: A61N1/36071 ,  A61B5/04001 ,  A61B5/4041 ,  A61B5/407 ,  A61B5/4821 ,  A61B5/4824 ,  A61B5/4836 ,  A61N1/0551 ,  A61N1/36139 ,  A61N1/3615

Abstract: An implantable device applies and controls a neural stimulus. The device has a plurality of electrodes, and a stimulus source for providing a stimulus to be delivered from the electrodes to a neural pathway in order to evoke an action potential on the neural pathway, such as the spinal cord. A control unit controls application of a neural stimulus as defined by a set of parameter values and measures via measurement circuitry an evoked neural compound action potential response. The control unit determines from the measured evoked response a feedback variable, and compares it to a therapy map. The therapy map defines a therapeutic relationship of control variable to feedback variable. One or more of the stimulus parameter values are altered to effect the required change in the control variable. This process is performed iteratively to improve alignment of the feedback variable with the therapy map over time.

Abstract translation: 可植入装置应用和控制神经刺激。 该装置具有多个电极和用于提供从电极传递到神经通路的刺激的刺激源，以便引起诸如脊髓的神经通路上的动作电位。 控制单元控制由一组参数值定义的神经刺激的应用，并通过测量电路测量诱发的神经复合动作电位响应。 控制单元根据所测量的诱发响应确定反馈变量，并将其与治疗图进行比较。 治疗图定义了控制变量与反馈变量的治疗关系。 刺激参数值中的一个或多个被改变以实现控制变量中所需的改变。 迭代地执行该过程以改善反馈变量与治疗映射随时间的对准。