Method for interfacing liquid chromatography-mass spectrometry systems
    1.
    发明授权
    Method for interfacing liquid chromatography-mass spectrometry systems 失效
    液相色谱 - 质谱系统接口方法

    公开(公告)号:US5447553A

    公开(公告)日:1995-09-05

    申请号:US326060

    申请日:1994-10-19

    摘要: Close coupled momentum separator with integral removable source volume for particle beam liquid chromatography/mass spectrometry is provided. The inventive PB LC/MS system comprises a momentum separator wherein the skimmers are designed to accommodate the particle beam conical dispersion so as to minimize the number of particles lost in the separator. In addition, the exit of the momentum separator is closely coupled to the entrance of the MS source volume. The PB LC/MS system demonstrates improved linearity in signal and enhanced sensitivity.

    摘要翻译: 提供了用于粒子束液相色谱/质谱的封闭耦合动量分离器和整体可移动源体积。 本发明的PB LC / MS系统包括动量分离器,其中撇渣器被设计成容纳颗粒束锥形分散体,以便最小化在分离器中损失的颗粒的数量。 此外,动量分离器的出口紧密耦合到MS源体积的入口。 PB LC / MS系统显示出信号线性度提高和灵敏度提高。