ASSAY
    1.
    发明申请
    ASSAY 审中-公开
    测定

    公开(公告)号:US20120070852A1

    公开(公告)日:2012-03-22

    申请号:US13132483

    申请日:2009-12-01

    IPC分类号: G01N21/64 B82Y15/00

    CPC分类号: C12Q1/48 C12Q1/485 G01N33/542

    摘要: The present invention relates to an assay for transferases. The assay comprises a first moiety comprising a transferase substrate and a second moiety capable of binding to the transferase substrate after it has been acted on by the transferase. One of the first and second moieties comprises a fluorophore and the other of the first and second moieties causes a change in fluorescence of the fluorophore. Thus, when the second moiety binds the transferase substrate after it has been acted on by the transferase, a change in fluorescence can be detected. The assay allows for agents that modulate the activity of the transferase to be screened.

    摘要翻译: 本发明涉及转移酶的测定。 该测定法包括第一部分,其包含转移酶底物和在被转移酶作用之后能够结合转移酶底物的第二部分。 第一和第二部分之一包含荧光团,第一和第二部分中的另一部分引起荧光团的荧光变化。 因此,当第二部分在被转移酶作用后结合转移酶底物时,可以检测到荧光的变化。 该测定允许调节转移酶活性的试剂被筛选。

    Biomaterials
    3.
    发明申请
    Biomaterials 审中-公开
    生物材料

    公开(公告)号:US20110123592A1

    公开(公告)日:2011-05-26

    申请号:US12994606

    申请日:2009-05-27

    摘要: The invention relates to a biomaterial having a latent form of a growth factor immobilised thereon, and to a method of producing the biomaterial, comprising immobilising the latent form of the growth factor on the biomaterial. The biomaterial may be used in medicine, such as in tissue regeneration or repair.

    摘要翻译: 本发明涉及具有固定在其上的生长因子的潜在形式的生物材料,以及生物材料的生产方法,包括将生长因子的潜在形式固定在生物材料上。 生物材料可用于医学中,例如在组织再生或修复中。