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公开(公告)号：US08865184B2
公开(公告)日：2014-10-21
申请号：US12439509
申请日：2007-08-31
Applicant: Murthy Krishna Ella , Kandaswamy Sumathy , Jaya Sheela Pydigummala , Nagendra R. Hegde
CPC classification number: C07K14/005 , A61K39/12 , A61K2039/5252 , C12N7/00 , C12N2710/14143 , C12N2770/36122 , C12N2770/36134 , C12N2770/36151 , C12N2770/36163 , Y02A50/383
Abstract: The present invention relates to vaccine formulation capable of eliciting protective immune response against Chikungunya virus infection in humans and other mammalian hosts. The immunogenic formulation comprises purified inactivated Chikungunya virus in a stable formulation. Methods of propagation and purification of the virus are discussed. The inactivated virus formulation is non-infectious, immunogenic and elicits protective immune response in mammalian host. The immunogenic composition is formulated for in vivo administration to humans. The invention also discusses the strategy of developing a subunit vaccine using the recombinant viral proteins as antigens for immunization. The recombinant virus antigens that are potentially immunogenic can be used in diagnosing for the presence of the virus.
Abstract translation: 本发明涉及能够在人和其他哺乳动物宿主中引起对基孔肯雅病毒感染的保护性免疫应答的疫苗制剂。 免疫原性制剂包含稳定制剂中纯化的灭活的基孔肯雅病毒。 讨论了病毒繁殖和纯化的方法。 灭活的病毒制剂是非传染性的，免疫原性的并且在哺乳动物宿主中引发保护性免疫应答。 免疫原性组合物被配制用于体内给予人。 本发明还讨论了使用重组病毒蛋白作为免疫的抗原开发亚单位疫苗的策略。 潜在免疫原性的重组病毒抗原可用于诊断病毒的存在。
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公开(公告)号：US08642107B2
公开(公告)日：2014-02-04
申请号：US12438344
申请日：2007-07-11
Applicant: Murthy Krishna Ella , Suchitra Ella , Alwar Ananda Purushotham Rudrapattana , Gopal Vinaya Kaippangala , Smita Singhania
Inventor： Murthy Krishna Ella , Suchitra Ella , Alwar Ananda Purushotham Rudrapattana , Gopal Vinaya Kaippangala , Smita Singhania
IPC: A23L2/00
CPC classification number: A61K8/965 , A23L2/56 , A23L27/12 , A61K8/97 , A61Q19/00 , C02F1/001 , C02F1/32 , C02F1/68 , C02F2103/026 , C02F2303/04
Abstract: A method and formulation for drinking water with herbal hint, in particular for packaged drinking water with herbal hint, is provided. The formulation includes water, wherein the water satisfies the pre-specified standards of drinking water. Further, the formulation includes one or more herbal ingredients. Also, the formulation includes essential oil of Rosemary to stabilize the formulation and hence to increase its shelf life.
Abstract translation: 提供了一种用草药提示饮用水的方法和配方，特别是含有草药提示的饮用水。 该制剂包括水，其中水满足预先规定的饮用水标准。 此外，制剂包含一种或多种草药成分。 此外，该制剂包括迷迭香精油以稳定制剂，从而增加其保质期。
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公开(公告)号：US20100009038A1
公开(公告)日：2010-01-14
申请号：US12438344
申请日：2007-07-11
Applicant: Murthy Krishna Ella , Suchitra Ella , Alwar Ananda Purushotham Rudrapattana , Gopal Vinaya Kaippangala , Smita Singhania
Inventor： Murthy Krishna Ella , Suchitra Ella , Alwar Ananda Purushotham Rudrapattana , Gopal Vinaya Kaippangala , Smita Singhania
IPC: A23L2/52
CPC classification number: A61K8/965 , A23L2/56 , A23L27/12 , A61K8/97 , A61Q19/00 , C02F1/001 , C02F1/32 , C02F1/68 , C02F2103/026 , C02F2303/04
Abstract: A method and formulation for drinking water with herbal hint, in particular for packaged drinking water with herbal hint, is provided. The formulation includes water, wherein the water satisfies the pre-specified standards of drinking water. Further, the formulation includes one or more herbal ingredients. Also, the formulation includes essential oil of Rosemary to stabilize the formulation and hence to increase its shelf life.
Abstract translation: 提供了一种用草药提示饮用水的方法和配方，特别是含有草药提示的饮用水。 该制剂包括水，其中水满足预先规定的饮用水标准。 此外，制剂包含一种或多种草药成分。 此外，该制剂包括迷迭香精油以稳定制剂，从而增加其保质期。
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