公开(公告)号：US11555016B2

公开(公告)日：2023-01-17

申请号：US17157916

申请日：2021-01-25

Applicant: Yongbo Wang ,  Han Li ,  Gennian Mao ,  Bin Tian ,  Dan Yang ,  Chengyuan Liang ,  Xiuding Yang ,  Wenbo Yao ,  Guaiping Qiao ,  Nan Hui ,  Juan Li ,  Liang Xin ,  Jingyi Li ,  Ruina Bian

Inventor： Yongbo Wang ,  Han Li ,  Gennian Mao ,  Bin Tian ,  Dan Yang ,  Chengyuan Liang ,  Xiuding Yang ,  Wenbo Yao ,  Guaiping Qiao ,  Nan Hui ,  Juan Li ,  Liang Xin ,  Jingyi Li ,  Ruina Bian

IPC: C07D215/233 ,  A61P31/04

Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. The methods of preparing the compound of formula (I) are also disclosed.

公开(公告)号：US11219652B2

公开(公告)日：2022-01-11

申请号：US16993599

申请日：2020-08-14

Applicant: Xiaolin Xie ,  Dezhu Zhang ,  Jianguo Meng ,  Yu Wang ,  Xuhua Zhou ,  Zhong Meng ,  Nan Hui ,  Juan Li

Inventor： Xiaolin Xie ,  Dezhu Zhang ,  Jianguo Meng ,  Yu Wang ,  Xuhua Zhou ,  Zhong Meng ,  Nan Hui ,  Juan Li

IPC: A61K36/16 ,  B01D11/02 ,  B01D37/00 ,  B01D21/26

Abstract: A method for extracting herbal medicine includes: step one, spray extraction; step two, pressure filtration and concentration; step three, spray and countercurrent precipitation; and step four, concentrating reduced pressure and drying.

公开(公告)号：US11155514B1

公开(公告)日：2021-10-26

申请号：US17128102

申请日：2020-12-19

Applicant: Bin Tian ,  Juan Li ,  Nan Hui ,  Guaiping Qiao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Han Li ,  Yanjun Li ,  Liang Qi ,  Wenbo Yao ,  Chengyuan Liang

Inventor： Bin Tian ,  Juan Li ,  Nan Hui ,  Guaiping Qiao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Han Li ,  Yanjun Li ,  Liang Qi ,  Wenbo Yao ,  Chengyuan Liang

IPC: C07C69/736 ,  C07C67/56 ,  C07C67/08

Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I) is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10947182B1

公开(公告)日：2021-03-16

申请号：US16914326

申请日：2020-06-27

Applicant: Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qiangian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

Inventor： Han Li ,  Nan Hui ,  Chengyuan Liang ,  Xingke Ju ,  Guaiping Qiao ,  Juan Li ,  Yuanyuan He ,  Bin Tian ,  Yongbo Wang ,  Jingwen Xu ,  Liang Qi ,  Dan Yang ,  Qiangian Zhao ,  Yanjun Li ,  Qiao Zeng ,  Gennian Mao ,  Limei Wang

IPC: C07C69/94

Abstract: A compound having the formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10717699B1

公开(公告)日：2020-07-21

申请号：US16845032

申请日：2020-04-09

Applicant: Lei Luo ,  Shinan Jiang ,  Yonghuang Luo ,  Han Li ,  Nan Hui

Inventor： Lei Luo ,  Shinan Jiang ,  Yonghuang Luo ,  Han Li ,  Nan Hui

IPC: C07C69/94 ,  C07C67/08

Abstract: A compound having the formula (I): (I) is disclosed. A method of preparing the compound of formula (I) is also disclosed.

公开(公告)号：US10343988B1

公开(公告)日：2019-07-09

申请号：US16359988

申请日：2019-03-20

Applicant: Chengyuan Liang ,  Lei Tian ,  Danni Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao

Inventor： Chengyuan Liang ,  Lei Tian ,  Danni Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao

IPC: C07C323/56 ,  C07C319/20 ,  C09K15/14

Abstract: A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US10336682B1

公开(公告)日：2019-07-02

申请号：US16359982

申请日：2019-03-20

Applicant: Chengyuan Liang ,  Lei Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao ,  Gennian Mao ,  Nan Qin ,  Juan Xia ,  Zhenfeng Shi

Inventor： Chengyuan Liang ,  Lei Tian ,  Yuzhi Liu ,  Xingke Ju ,  Nan Hui ,  Mi Wu ,  Juan Li ,  Han Li ,  Bin Tian ,  Qianqian Zhao ,  Gennian Mao ,  Nan Qin ,  Juan Xia ,  Zhenfeng Shi

IPC: C07C69/757 ,  B01J31/02 ,  C07C67/08

Abstract: A compound having the following formula I: is disclosed. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US20090325775A1

公开(公告)日：2009-12-31

申请号：US12388095

申请日：2009-02-18

Applicant: Nan-Hui Yeh

Inventor： Nan-Hui Yeh

IPC: C03C14/00 ,  C03C3/32

CPC classification number: C03C14/006 ,  A61L27/10 ,  C03C10/00 ,  C03C12/00

Abstract: A method for manufacturing a bioactive glass ceramic material is firstly to prepare a calcium phosphate series ceramic material and a nano-scaled titanium dioxide powder with a specific proportion of anatase type titanium dioxide structure. Then, the calcium phosphate series ceramic material and the nano-scaled titanium dioxide powder are mixed according to a specific proportion for obtaining a mixture. The mixture is then melted and quenched to form a biomedical glass. Finally, the biomedical glass can be further ground into a biomedical glass powder, and a heat treatment can be applied to recrystalize the powder so as to obtain the bioactive glass ceramic material. Also, the bioactive glass ceramic material can be further polarized into a electrified bioactive glass ceramic material which can promote the growth of a broken bone.

Abstract translation: 一种制备生物活性玻璃陶瓷材料的方法首先是制备一种具有特定比例的锐钛矿型二氧化钛结构的磷酸钙系陶瓷材料和纳米级二氧化钛粉末。 然后，根据特定比例将磷酸钙系陶瓷材料和纳米级二氧化钛粉末混合以获得混合物。 然后将混合物熔化并骤冷以形成生物医学玻璃。 最后，生物医学玻璃可以进一步研磨成生物医学玻璃粉末，并且可以进行热处理以使粉末重结晶，从而获得生物活性玻璃陶瓷材料。 此外，生物活性玻璃陶瓷材料可以进一步极化成带电的生物活性玻璃陶瓷材料，其可以促进破骨的生长。

公开(公告)号：US06531589B1

公开(公告)日：2003-03-11

申请号：US08598320

申请日：1996-02-08

Applicant: Radhakrishnan P. Iyer ,  Theresa Devlin ,  Ivan Habus ,  Dong Yu ,  Sudhir Agrawal ,  Nan-Hui Ho

Inventor： Radhakrishnan P. Iyer ,  Theresa Devlin ,  Ivan Habus ,  Dong Yu ,  Sudhir Agrawal ,  Nan-Hui Ho

IPC: C07H2100

CPC classification number: C07H19/10 ,  C07H19/16 ,  C07H19/20 ,  C07H21/00 ,  Y02P20/55

Abstract: The invention provides new methods for synthesizing oligonucleotides that allow for deprotection of the oligonucleotides under more mild conditions than existing methods. The invention further provides a nucleoside base protecting group that is stable under oligonucleotide synthesis conditions, but which can be removed under more mild conditions than existing protecting groups, as well as nucleoside synthons having such base protecting groups.

Abstract translation: 本发明提供了合成寡核苷酸的新方法，其允许在比现有方法更温和的条件下对寡核苷酸进行脱保护。 本发明还提供了在寡核苷酸合成条件下稳定但可在比现有保护基更温和的条件下除去的核苷碱保护基，以及具有这种碱保护基的核苷合成子。

公开(公告)号：US11597714B2

公开(公告)日：2023-03-07

申请号：US17128103

申请日：2020-12-19

Applicant: Chengyuan Liang ,  Cong Du ,  Qianqian Zhao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Nan Hui ,  Guaiping Qiao ,  Han Li ,  Yanjun Li ,  Liang Qi ,  Wenbo Yao ,  Gennian Mao

Inventor： Chengyuan Liang ,  Cong Du ,  Qianqian Zhao ,  Liang Xin ,  Jingyi Li ,  Dan Yang ,  Nan Hui ,  Guaiping Qiao ,  Han Li ,  Yanjun Li ,  Liang Qi ,  Wenbo Yao ,  Gennian Mao

IPC: C07D339/04 ,  A61P31/04

Abstract: A compound with anti-drug resistant bacteria activity having the following formula (I): is disclosed. A method of preparing the compound of formula (I) is also disclosed.