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    SYSTEM AND METHOD FOR MANIPULATING INSERTION PATHWAYS FOR ACCESSING TARGET SITES
    5.
    发明申请
    SYSTEM AND METHOD FOR MANIPULATING INSERTION PATHWAYS FOR ACCESSING TARGET SITES 有权
    用于操纵目标站点的插入路径的系统和方法

    公开(公告)号：US20120035590A1

    公开(公告)日：2012-02-09

    申请号：US13248922

    申请日：2011-09-29

    申请人： James S. Whiting ,  Neal L. Eigler ,  Brian M. Mann ,  Werner Hafelfinger

    发明人： James S. Whiting ,  Neal L. Eigler ,  Brian M. Mann ,  Werner Hafelfinger

    IPC分类号： A61M25/09

    CPC分类号： A61B17/3468 ,  A61B2017/00243 ,  A61M25/01 ,  A61M25/09 ,  A61M2025/0681 ,  A61N1/056

    摘要： A method for accessing a target site in the body by transferring a guidewire from an initial insertion site on the body to a different insertion site on the body is provided. In one aspect, a method for transferring a medical device or component, such as a sensor lead, from an initial insertion site to another insertion site is also provided. A guidewire of sufficient length, pliancy and deformability to perform a transfer from one insertion site to another insertion site is provided. In one aspect, the guidewire comprises a removable core mandrel to increase rigidity, facilitate insertion and/or improve steerability. A kit or system, comprising introducers, guidewires and catheters for performing a guidewire or device transfer is also provided.

    摘要翻译： 提供了一种通过将导丝从身体上的初始插入位置传递到身体上的不同插入位置来访问身体中的目标部位的方法。 一方面，还提供了用于将诸如传感器引线的医疗装置或部件从初始插入位置转移到另一插入位置的方法。 提供了足够的长度，柔软度和变形性的导线，以执行从一个插入位点到另一个插入位点的转移。 在一个方面，导丝包括可移除的芯心，以增加刚性，便于插入和/或提高可操纵性。 还提供了一种套件或系统，其包括用于执行导丝或设备转移的导引器，导线和导管。

    Transmembrane access systems and methods
    6.
    发明授权
    Transmembrane access systems and methods 有权
    跨膜进入系统和方法

    公开(公告)号：US08029470B2

    公开(公告)日：2011-10-04

    申请号：US10956899

    申请日：2004-09-30

    申请人： James S. Whiting ,  Neal L. Eigler ,  John L. Wardle ,  Werner Hafelfinger ,  Brian Mann

    发明人： James S. Whiting ,  Neal L. Eigler ,  John L. Wardle ,  Werner Hafelfinger ,  Brian Mann

    IPC分类号： A61M5/178

    CPC分类号： A61M25/0662 ,  A61M25/0041 ,  A61M2025/0681

    摘要： Systems and methods for penetrating a tissue membrane to gain access to a target site are disclosed. In some examples, systems and methods for accessing the left atrium from the right atrium of a patient's heart are carried out by puncturing the intra-atrial septal wall. One embodiment provides a system for transseptal cardiac access that includes a stabilizer sheath having a side port, a shaped guiding catheter configured to exit the side port and a tissue penetration member disposed within and extendable from the distal end of the guide catheter. The tissue penetration member may be configured to penetrate tissue upon rotation and may be coupled to a distal portion of a torqueable shaft. In some embodiments, the stabilizer sheath and shaped guiding catheter may be moved relative to the patient's body structure and relative to each other so that a desired approach angle may be obtained for the tissue penetration member with respect to the target tissue.

    摘要翻译： 公开了渗透组织膜以获得进入目标部位的系统和方法。 在一些实例中，通过穿刺房间隔壁来进行从患者心脏的右心房进入左心房的系统和方法。 一个实施例提供了一种用于经心脏进入的系统，其包括具有侧端口的稳定器护套，被配置为离开侧端口的成形引导导管和设置在引导导管的远端内并且可从引导导管的远端延伸的组织穿透构件。 组织穿透构件可以构造成在旋转时穿透组织并且可以联接到可扭转轴的远侧部分。 在一些实施例中，稳定器护套和成形引导导管可以相对于患者的身体结构相对于彼此移动，使得组织穿透构件相对于目标组织可以获得期望的接近角。

    Coronary tracking display
    7.
    发明授权
    Coronary tracking display 失效

    公开(公告)号：US5822391A

    公开(公告)日：1998-10-13

    申请号：US555673

    申请日：1996-03-25

    申请人： James S. Whiting ,  Neal L. Eigler

    发明人： James S. Whiting ,  Neal L. Eigler

    IPC分类号： A61B6/00 ,  A61M25/01 ,  G06T7/00 ,  G06T7/20 ,  H04N5/32 ,  H04N5/325 ,  H05G1/60 ,  H05G1/64

    CPC分类号： A61B6/481 ,  A61B6/504 ,  G06T7/004 ,  G06T7/20 ,  G06T7/2033 ,  H04N5/3205 ,  H04N5/325 ,  H05G1/60 ,  G06T2207/30101

    摘要： A method of displaying details of a coronary artery lesion in a cineangiogram, by adjusting each frame of the cineangiogram so that the lesion is continually displayed at a fixed location on a display. The remaining cardiac anatomy appears to move, in background, past a stationary arterial segment, thus making the displayed arterial segment easier to identify and to examine by medical personnel. Cineangiographic image frames are digitized and processed by a processor and the image frames are digitally shifted to place the arterial segment in substantially the same viewing location in each frame. Sequential image frames may be presented to the viewer as a stereoscopic pair, to produce pseudostereopsis. The arterial segment appears to the viewer in foreground, as if it was floating in front of the remaining cardiac anatomy. Image frames may be further processed to aid examination by medical personnel. The processor may make quantitative measurements of the cineangiogram and may display results of those measurements to aid review of the cineangiogram. Frames may be averaged to reduce quantum noise and to blur any structure noise; frames may be compared with prior cineangiograms to increase clarity or contrast. Coordinate adjustments for a cineangiogram may help guide therapeutic procedures, or may help enhance other imaging procedures such as fluoroscopy.

    Expandable medical device with beneficial agent in openings
    9.
    发明授权
    Expandable medical device with beneficial agent in openings 有权
    具有开口的有益剂的可扩展医疗器械

    公开(公告)号：US08202313B2

    公开(公告)日：2012-06-19

    申请号：US10849324

    申请日：2004-05-19

    申请人： John F. Shanley ,  Neal L. Eigler ,  Elazer R. Edelman

    发明人： John F. Shanley ,  Neal L. Eigler ,  Elazer R. Edelman

    IPC分类号： A61F2/82

    CPC分类号： A61F2/91 ,  A61F2/915 ,  A61F2002/91533 ,  A61F2002/91558 ,  A61F2250/0004 ,  A61F2250/0068

    摘要： An expandable medical device having a plurality of elongated struts, the plurality of elongated struts being joined together by ductile hinges to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. The plurality of struts and ductile hinges are arranged to improve the spatial distribution of the struts which is particularly important when delivering beneficial agents with the struts. The improved strut arrangement expands to a substantially parallelogram shape for improved beneficial agent distribution to the surrounding tissue. A beneficial agent may be loaded into openings within the struts or coated onto the struts for delivery to the tissue.

    摘要翻译： 一种具有多个细长支柱的可扩张医疗装置，所述多个细长支柱通过延性铰链连接在一起以形成可从具有第一直径的圆柱体膨胀至具有第二直径的圆柱体的基本上圆柱形的装置。 多个支柱和延性铰链被布置成改善支柱的空间分布，这在用支柱输送有益试剂时是特别重要的。 改进的支柱布置扩展到基本上平行四边形的形状，以改善对周围组织的有益剂分布。 有益剂可以装载到支柱内的开口中或涂覆到支柱上以输送到组织。

    HEMOSTASIS VALVE WITH IRIS SEAL
    10.
    发明申请
    HEMOSTASIS VALVE WITH IRIS SEAL 有权
    HEMOSTASIS阀与IRIS密封

    公开(公告)号：US20110054405A1

    公开(公告)日：2011-03-03

    申请号：US12552199

    申请日：2009-09-01

    申请人： James S. Whiting ,  Werner Hafelfinger ,  Neal L. Eigler ,  John L. Wardle

    发明人： James S. Whiting ,  Werner Hafelfinger ,  Neal L. Eigler ,  John L. Wardle

    IPC分类号： A61B17/34

    CPC分类号： A61B17/3462 ,  A61B17/3439 ,  A61M39/0613

    摘要： A hemostasis valve is disclosed herein. The hemostasis valve may include an inner bushing, a rotation sleeve, an elastomeric sleeve, and a biasing element. The rotation sleeve may extend about the inner bushing and be rotationally displaceable relative to the inner bushing. The elastomeric sleeve may include a first end operably coupled to the inner bushing, a second end operably coupled to the rotation sleeve, and an iris valve portion. Rotation of the rotation sleeve relative to the inner bushing may cause the iris valve to transition from an open state to a closed state. The biasing element may act between the rotation sleeve and inner bushing to bias the iris valve towards at least one of a closed state or an open state.

    摘要翻译： 本文公开了一种止血阀。 止血阀可以包括内衬套，旋转套筒，弹性体套筒和偏置元件。 旋转套筒可以围绕内衬套延伸并且可相对于内衬套旋转移位。 弹性体套筒可以包括可操作地联接到内衬套的第一端，可操作地联接到旋转套筒的第二端和可变光阀部分。 旋转套筒相对于内衬套的旋转可能导致虹膜阀从打开状态转换到关闭状态。 偏置元件可以在旋转套筒和内衬套之间作用，以将虹膜阀朝向关闭状态或打开状态中的至少一个偏压。