公开(公告)号：US20050080135A1

公开(公告)日：2005-04-14

申请号：US10682004

申请日：2003-10-08

申请人： Nirmal Koshti ,  Shubhangi Naik ,  Bharat Parab ,  Tanaji Jadhav ,  Subhash Nashte

发明人： Nirmal Koshti ,  Shubhangi Naik ,  Bharat Parab ,  Tanaji Jadhav ,  Subhash Nashte

IPC分类号： A61K31/205 ,  C07C231/12 ,  C07C235/34 ,  C07C237/36 ,  C07C39/29

CPC分类号： A61K31/205 ,  C07C231/12 ,  C07C235/34 ,  C07C237/36

摘要： An efficient, simple, high yielding, eco-friendly process for the manufacture of tosylates quaternary ammonium salts of cinnamidoalkylamines and/or benzamidoalkylamines (Formula I) has been described. These compounds are substantive UV-absorbers. They are useful in making fabric care products and personal care products. The scope of this methodology has been demonstrated by converting water soluble organic sunscreen quaternary halides to their corresponding tosylates of Formula VI.

摘要翻译： 已经描述了用于制造肉豆蔻酰烷基胺和/或苯甲酰胺基烷基胺的甲苯磺酸盐季铵盐的有效，简单，高产，环保的方法（式I）。 这些化合物是实质的紫外线吸收剂。 它们可用于制作织物护理产品和个人护理产品。 通过将水溶性有机防晒季铵盐转化成其相应的式VI的甲苯磺酸酯已经证明了该方法的范围。

公开(公告)号：US20050209327A1

公开(公告)日：2005-09-22

申请号：US11128980

申请日：2005-05-13

申请人： Nirmal Koshti ,  Shubhangi Naik ,  Bharat Parab ,  Tanaji Jadhav ,  Subhash Nashte

发明人： Nirmal Koshti ,  Shubhangi Naik ,  Bharat Parab ,  Tanaji Jadhav ,  Subhash Nashte

IPC分类号： A61K31/205 ,  C07C231/12 ,  C07C235/34 ,  C07C237/36

CPC分类号： A61K31/205 ,  C07C231/12 ,  C07C235/34 ,  C07C237/36

摘要： An efficient, simple, high yielding, eco-friendly process for the manufacture of tosylates quaternary ammonium salts of cinnamidoalkylamines and/or benzamidoalkylamines (Formula I) has been described. These compounds are substantive UV-absorbers. They are useful in making fabric care products and personal care products. The scope of this methodology has been demonstrated by converting water soluble organic sunscreen quaternary halides to their corresponding tosylates of Formula VI.

摘要翻译： 已经描述了用于制造肉豆蔻酰烷基胺和/或苯甲酰胺基烷基胺的甲苯磺酸盐季铵盐的有效，简单，高产，环保的方法（式I）。 这些化合物是实质的紫外线吸收剂。 它们可用于制作织物护理产品和个人护理产品。 通过将水溶性有机防晒季铵盐转化成其相应的式VI的甲苯磺酸酯已经证明了该方法的范围。

公开(公告)号：US20070004801A1

公开(公告)日：2007-01-04

申请号：US11327202

申请日：2006-01-06

申请人： Nirmal Koshti ,  Bharat Parab ,  Shubhangi Naik

发明人： Nirmal Koshti ,  Bharat Parab ,  Shubhangi Naik

IPC分类号： A61K31/205 ,  C07C237/02

CPC分类号： C07C231/12 ,  A61K31/205 ,  C07C233/36

摘要： An aqueous composition for oral care application comprising solution of an amidobetaine of the following general Formula I is disclosed; in which R is an alkyl of coconut fatty acids, preferably hydrogenated coconut fatty acids, or a fatty acid mixture group which, on the average, corresponds to coconut fatty acids, wherein the solution has a solids content of 36% by weight, a pH of 4.5 to 6, an alkylamidopropyldimethyl amine content of not more than 0.1% by weight, and a free fatty acid content less than 0.5% by weight, sodium chloride content of 6.0% max and dimethylaminopropylamino betaine (from N,N-dimethyl amino propyl 1,3-diamine (DMAPA) and monochloroacetic acid) content of 30 ppm max, free sodium monochloroacetic acid content of 5 ppm max and free N,N-dimethylamino propyl 1,3-diamine content of 5.0 ppm max.

摘要翻译： 公开了一种用于口腔护理应用的含水组合物，其包含以下通式I的氨基甜菜碱溶液; 其中R是椰子脂肪酸的烷基，优选氢化椰子脂肪酸，或平均相当于椰子脂肪酸的脂肪酸混合物组，其中溶液的固体含量为36重量％，pH 为4.5〜6，烷基酰胺基丙基二甲基胺含量为0.1重量％以下，游离脂肪酸含量小于0.5重量％，氯化钠含量为6.0％以上，二甲基氨基丙基氨基甜菜碱（来自N，N-二甲基氨基丙基 1,3-二胺（DMAPA）和一氯乙酸）含量最高为30ppm，游离的一氯乙酸含量最高为5ppm，游离的N，N-二甲基氨基丙基1,3-二胺的含量最高为5.0ppm。

公开(公告)号：US20130101530A1

公开(公告)日：2013-04-25

申请号：US13400462

申请日：2012-02-20

申请人： Nirmal KOSHTI ,  Shraddha Kiran RATNAPARKHE ,  Devyani Ashok MALI ,  Bhagyesh SAWANT ,  Pooja Dinkar VAIDYA

发明人： Nirmal KOSHTI ,  Shraddha Kiran RATNAPARKHE ,  Devyani Ashok MALI ,  Bhagyesh SAWANT ,  Pooja Dinkar VAIDYA

IPC分类号： A61K8/92 ,  A01N37/20 ,  A61Q19/00 ,  A61Q5/02 ,  A61Q17/04 ,  A01N37/46 ,  A01P1/00

CPC分类号： A01N37/44 ,  A01N31/14 ,  A01N37/20 ,  A01N37/46 ,  A61K8/33 ,  A61K8/34 ,  A61K8/345 ,  A61K8/42 ,  A61K8/44 ,  A61K2800/5922 ,  A61Q5/02 ,  A61Q9/02 ,  A61Q17/005 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/10 ,  A01N2300/00

摘要： A personal product antimicrobial preservative composition for preservation of topical personal care formulations is provided comprising [A] one or more undecylenic acid derivatives depicted by Formula (I), [B] one or more octanoic acid derivatives depicted by Formula (II), and [C] 2-phenoxy ethanol or 2-ethyl hexyl glyceryl ether or mixture of these two ‘liquid alcohol ethers’; wherein, each of the two components [A] and [B] is present in the range of 5 to 20% by weight and together [A] and [B] constitute 10 to 30% by weight and the ‘liquid alcohol ether’, component [C], is present 70 to 90% by weight of the total preservative composition. A method for preserving personal care product from microbial attack is provided containing an aqueous phase comprising three component composition from about 0.5 to 2.5% by weight of the total personal care formulation.

摘要翻译： 提供了用于保护局部个人护理制剂的个人产品抗微生物防腐组合物，其包含[A]一种或多种由式（I）表示的十一碳烯酸衍生物，[B]式（II）所示的一种或多种辛酸衍生物和[ C] 2-苯氧基乙醇或2-乙基己基甘油醚或这两种“液体醇醚”的混合物; 其中，两种组分[A]和[B]中的每一种以5至20重量％的范围存在，[A]和[B]的组成为10至30重量％，“液体醇醚” 组分[C]占总防腐剂组合物的70〜90重量％。 提供了一种保护个人护理产品免受微生物攻击的方法，其含有包含三种组分组合物的水相，所述组合物占总个人护理制剂的约0.5至2.5重量％。

公开(公告)号：US07534816B2

公开(公告)日：2009-05-19

申请号：US11327202

申请日：2006-01-06

申请人： Nirmal Koshti ,  Bharat Parab ,  Shubhangi Naik

发明人： Nirmal Koshti ,  Bharat Parab ,  Shubhangi Naik

IPC分类号： A01N37/30 ,  A61K31/205

CPC分类号： C07C231/12 ,  A61K31/205 ,  C07C233/36

摘要： An aqueous composition for oral care application comprising solution of an amidobetaine of the following general Formula I is disclosed; in which R is an alkyl of coconut fatty acids, preferably hydrogenated coconut fatty acids, or a fatty acid mixture group which, on the average, corresponds to coconut fatty acids, wherein the solution has a solids content of 36% by weight, a pH of 4.5 to 6, an alkylamidopropyldimethyl amine content of not more than 0.1% by weight, and a free fatty acid content less than 0.5% by weight, sodium chloride content of 6.0% max and dimethylaminopropylamino betaine (from N,N-dimethyl amino propyl 1,3-diamine (DMAPA) and monochloroacetic acid) content of 30 ppm max, free sodium monochloroacetic acid content of 5 ppm max and free N,N-dimethylamino propyl 1,3-diamine content of 5.0 ppm max.

摘要翻译： 公开了一种用于口腔护理应用的含水组合物，其包含以下通式I的氨基甜菜碱溶液; 其中R是椰子脂肪酸的烷基，优选氢化椰子脂肪酸，或平均相当于椰子脂肪酸的脂肪酸混合物组，其中溶液的固体含量为36重量％，pH 为4.5〜6，烷基酰胺基丙基二甲基胺含量为0.1重量％以下，游离脂肪酸含量小于0.5重量％，氯化钠含量为6.0％以上，二甲基氨基丙基氨基甜菜碱（来自N，N-二甲基氨基丙基 1,3-二胺（DMAPA）和一氯乙酸）含量最高为30ppm，游离的一氯乙酸含量最高为5ppm，游离的N，N-二甲基氨基丙基1,3-二胺的含量最高为5.0ppm。

公开(公告)号：US20060128596A1

公开(公告)日：2006-06-15

申请号：US11010762

申请日：2004-12-13

申请人： Nirmal Koshti ,  Bharat Parab ,  Subhash Nashte

发明人： Nirmal Koshti ,  Bharat Parab ,  Subhash Nashte

IPC分类号： C11D1/10

CPC分类号： C11D1/94 ,  C11D1/52 ,  C11D1/90

摘要： An aqueous composition comprising solution of a betaine of the following general Formula I is disclosed Formula I in which R is an alkyl group of coconut fatty acids, preferably hydrogenated coconut fatty acids, or a fatty acid mixture which, on the average, corresponds to coconut fatty acids, wherein the solution has a solids content of at least 45% by weight, a pH of 4.5 to 8, an amidoamine content of not more than 1% by weight, and a free fatty acid content less than 1% by weight, an N-acyl α-aminoacids content between 0.5 to 3% by weight and 0 to 4% by weight of glycerin, based on the solution.

摘要翻译： 公开了含有下列通式I的甜菜碱溶液的含水组合物：其中R为椰子脂肪酸烷基，优选氢化椰子脂肪酸或平均相当于椰子的脂肪酸混合物 脂肪酸，其中所述溶液的固体含量为至少45重量％，pH为4.5至8，酰胺胺含量不超过1重量％，游离脂肪酸含量小于1重量％ 基于溶液，N-酰基α-氨基酸含量为0.5-3重量％和0-4重量％甘油。

公开(公告)号：US20060067893A1

公开(公告)日：2006-03-30

申请号：US10953832

申请日：2004-09-29

申请人： Nirmal Koshti ,  Shubhangi Naik ,  Tanaji Jadhav

发明人： Nirmal Koshti ,  Shubhangi Naik ,  Tanaji Jadhav

IPC分类号： C07C309/30 ,  A61K8/46

CPC分类号： A61Q5/12 ,  A61K8/14 ,  A61K8/42 ,  A61K8/466 ,  A61Q17/04

摘要： Highly effective vesicular compositions from UV-absorbing lipids are described in the present invention. Combination of UV-absorbing property and the vesicular delivery system results in higher levels of photoprotection to skin and hair. The vesicular compositions of the present invention are made from cationic UV-absorbing lipids of Formula I wherein, ArCO is selected from cinnamoyl, p-methoxy cinnamoyl, p-N,N-dimethylamino benzoyl and combinations thereof, R1 is selected from saturated or unsaturated alkyl group with carbons ranging from C10 to C22.

摘要翻译： 在本发明中描述了来自UV吸收型脂质的高效囊泡组合物。 紫外线吸收性能和水泡传播系统的组合导致对皮肤和头发的更高水平的光保护。 本发明的囊状组合物由式I的阳离子紫外线吸收脂质制成，其中，