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1.发明授权
公开(公告)号：US4985412A
公开(公告)日：1991-01-15
申请号：US260868
申请日：1988-10-21
IPC分类号： A61K8/06 , A61K8/00 , A61K8/55 , A61K8/58 , A61Q5/02 , A61Q19/10 , C07F9/09 , C08G65/32 , C11D1/78 , C11D1/88 , C11D3/36
摘要： Phosphoric acid esters represented by the following formulae (I) and (IX) as well as processes for preparing them are disclosed. ##STR1## wherein R.sub.1 represents a linear or branched, alkyl or alkenyl group having a C.sub.1-36 carbon atom content, with or without the hydrogen atom(s) being substituted with fluorine atom(s), or a phenyl group with substituted linear or branched alkyl group(s) having a C.sub.1-15 carbon atom content, R.sub.2 represents an alkylene group having a C.sub.2-3 carbon atom content, R.sub.3 and R.sub.4 independently denote a hydrogen atom or an alkyl group having a C.sub.1-3 carbon atom content, R.sub.5 and R.sub.6 independently denote a hydrogen atom, or an alkyl, alkenyl, or phenyl group with or without the hydrogen atom(s) being substituted with group(s) containing hetero atom(s), excepting for a mercapto group, R.sub.7 and R.sub.8 independently denote a hydrogen atom, or an alkyl, or alkenyl group, m is an integer of 0-30, n is an integer of 0-5, l is an integer of 0-3, M is a hydrogen atom, an alkali metal, an alkali earth metal, on ammonium group, an alkyl amine group, or an alkanol amine group. The phosphoric acid ester have outstanding surface activity and good foaming capability, and imparts only extremely low irritation to the skin. The detergent composition into which they are formulated is particularly useful as, shampoo, baby shampoo, body shampoo.
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公开(公告)号：US5409705A
公开(公告)日：1995-04-25
申请号：US796337
申请日：1991-11-22
申请人： Katsumi Kita , Mitsuru Uno , Hiroshi Kamitani , Yoshiaki Fujikura , Nobutaka Horinishi , Tomohito Kitsuki , Kazuyasu Imai , Yasushi Kajihara
发明人： Katsumi Kita , Mitsuru Uno , Hiroshi Kamitani , Yoshiaki Fujikura , Nobutaka Horinishi , Tomohito Kitsuki , Kazuyasu Imai , Yasushi Kajihara
IPC分类号： C07F9/09 , C07F9/655 , C07H11/04 , C07H15/04 , C08B31/06 , C11D1/88 , C11D3/22 , C11D3/36 , C07C69/76 , A61K7/06 , C07H15/00
CPC分类号： C11D3/364 , A61K8/55 , A61Q19/00 , C07F9/091 , C07F9/65515 , C07H11/04 , C07H15/04 , C08B31/066 , C11D1/886 , C11D3/228 , A61Q19/10 , A61Q5/00 , A61Q5/006 , A61Q5/02
摘要： A novel phosphobetaine is disclosed. This compound is very excellence in that it exerts a conditioning effect of imparting a good feel to the skin or hair, is excellent in humidifying properties, is available at a low price, and thus it is highly usable in detergents, cosmetics, a bathing preparation and the like. A detergent composition, a cosmetic, and a bathing preparation each containing the phosphobetaine are also disclosed.
摘要翻译： 公开了一种新的磷酸甜菜碱。 该化合物非常优异地发挥赋予皮肤或毛发良好感觉的调理效果，加湿性优异，可以低价位获得，因此其可用于洗涤剂，化妆品，洗浴用品 等等。 还公开了含有磷酸甜菜碱的洗涤剂组合物，化妆品和洗浴剂。
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3.发明授权
公开(公告)号：US5071585A
公开(公告)日：1991-12-10
申请号：US604172
申请日：1990-10-29
IPC分类号： A61K8/06 , A61K8/00 , A61K8/55 , A61K8/58 , A61Q5/02 , A61Q19/10 , C07F9/09 , C08G65/32 , C11D1/78 , C11D1/88 , C11D3/36
摘要： Phosphoric acid esters represented by the following formulae (I) and (IX) as well as processes for preparing them are disclosed. ##STR1## wherein R.sub.1 represents a linear or branched, alkyl or alkenyl group having a C.sub.1-36 carbon atom content, with or without the hydrogen atom(s) being substituted with fluorine atom(s), or a phenyl group with substituted linear or branched alkyl group(s) having a C.sub.1-15 carbon atom content, R.sub.2 represents an alkylene group having a C.sub.2-3 carbon atom content, R.sub.3 and R.sub.4 independently denote a hydrogen atom or an alkyl group having a C.sub.1-3 carbon atom content, R.sub.5 and R.sub.6 independently denote a hydrogen atom, or an alkyl, alkenyl, or phenyl group with or without the hydrogen atom(s) being substituted with group(s) containing hetero atom(s), excepting for a mercapto group, R.sub.7 and R.sub.8 independently denote a hydrogen atom, or an alkyl, or alkenyl group, m is an integer of 0-30, n is an integer of 0-5, l is an integer of 0-3, M is a hydrogen atom, an alkali metal, an alkali earth metal, an ammonium group, an alkyl amine group, or an alkanol amine group. The phosphoric acid esters have outstanding surface activity and good foaming capability, and imparts only extremely low irritation to the skin. The detergent composition into which they are formulated is particularly useful as, shampoo, baby shampoo, body shampoo.
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4.发明授权Modification method for peptides and proteins by reacting with a phosphoric acid ester 失效通过与磷酸酯反应来改变肽和蛋白质的方法
公开(公告)号：US5043424A
公开(公告)日：1991-08-27
申请号：US260709
申请日：1988-10-21
IPC分类号： C07K14/655 , C07K1/00 , C07K1/02 , C07K1/107 , C07K1/113 , C07K1/14 , C07K4/00 , C07K5/06 , C07K14/00 , C07K14/575 , C07K14/76 , C07K16/00 , C12N9/16 , C12N9/96
CPC分类号： C07K5/06191 , C07K1/1077
摘要： A peptide or protein is modified by reacting a phosphoric acid ester represented by the following general formula (I) with a peptide or protein: ##STR1## wherein R.sub.1 means a linear or branched, C.sub.1-36 alkyl or C.sub.2-36 alkenyl group whose hydrogen atom or atoms may be substituted by the corresponding number of fluorine atom(s) or a phenyl group substituted by at least one linear or branched C.sub.1-15 alkyl group, R.sub.2 denotes a C.sub.2-3 alkylene group, m stands for a number of 0-30, and M is a hydrogen atom, an alkali metal ion, an alkaline earth metal ion, an ammonium ion, an alkylamine residue or an alkanolamine residue.
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公开(公告)号：US5403517A
公开(公告)日：1995-04-04
申请号：US163539
申请日：1993-12-09
IPC分类号： A61K8/00 , A61K8/34 , A61K8/36 , A61K8/365 , A61K8/39 , A61Q5/00 , A61Q5/02 , C11D1/29 , A61K7/075
摘要： Hair care compositions which contain the following ingredients (a) and (b):(a) an alpha-hydroxymonocarboxylic acid represented by the formula (1) or a salt thereof, ##STR1## wherein R' is a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or a salt thereof; and(b) an aromatic alcohol represented by the formula (2) ##STR2## wherein R.sup.2 is a hydrogen atom, a methyl or a methoxy group, X represents a single bond or a linear or branched alkylene or alkenylene group having 1 to 3 carbon atoms, Y is a hydrogen atom or a hydroxyl group, and p and q independently represent a number from 0 to 5, provide excellent sensation upon use, impart long-lasting softness to the hair, in particular to solid or stiff hair, and provide easy manageability and handling of the hair for a desired hairdo.
摘要翻译： 含有以下组分（a）和（b）的头发护理组合物：（a）由式（1）表示的α-羟基单羧酸或其盐，其中R'是氢原子或 具有1至4个碳原子的烷基或其盐; 和（b）由式（2）表示的芳族醇其中R 2是氢原子，甲基或甲氧基，X代表单键或具有1个碳原子的直链或支链亚烷基或亚烯基 3个碳原子，Y是氢原子或羟基，p和q独立地表示0至5的数字，在使用时提供优异的感觉，赋予头发长久的柔软性，特别是固体或硬的头发 ，并提供易于管理和处理头发的所需发型。
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