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公开(公告)号：USD733474S1
公开(公告)日：2015-07-07
申请号：US29446565
申请日：2013-02-25
设计人： Mark C. Fishman , Toshiko Mori , Landon S. Brown
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公开(公告)号：US20140238277A1
公开(公告)日：2014-08-28
申请号：US13801388
申请日：2013-03-13
发明人： Mark C. FISHMAN , Toshiko MORI , Landon S. BROWN
CPC分类号： A47B37/00 , A47B13/003 , A47B21/06 , A47B2021/064 , A47B2037/005 , B01L9/02 , B01L2200/028
摘要： Modular laboratory workbenches and work surface accessories are provided. Modular laboratory workbenches may include a spine structure including multiple modules with core passageways for routing utilities. At least one spine structure module may include circuit breakers behind a panel for local electrical power control. The spine structure may include a top with angled faces that provide power outlets, gas terminals, and other utilities. Between angled faces, an accessory support structure may be provided that supports a backsplash in a center channel and provides accessory slots on both sides of the center channel to receive and support interchangeable accessories including monitor arms, tablet arms, gas turrets, supplemental lights, etc. Cantilever brackets of various heights may attach to the spine structure and support work surfaces that are translatable to provide access to the utilities provided on the angled faces of the spine structure.
摘要翻译： 提供模块化实验室工作台和工作台面附件。 模块化实验室工作台可以包括脊柱结构，其包括具有用于路由实用程序的核心通道的多个模块。 至少一个脊柱结构模块可以包括用于局部电力控制的面板后面的断路器。 脊柱结构可以包括顶部，其具有提供电源插座，气体端子和其它用途的成角度的面。 在倾斜面之间，可以提供支撑中心通道中的后挡板的附件支撑结构，并且在中心通道的两侧提供附件槽，以接收和支撑可互换的附件，包括监视器臂，平板臂，气炮塔，补充灯等 各种高度的悬臂支架可以附着在脊柱结构上并支撑可平移的工作表面，以提供对脊柱结构的倾斜面上提供的用途的访问。
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公开(公告)号：US09055812B2
公开(公告)日：2015-06-16
申请号：US13801388
申请日：2013-03-13
发明人： Mark C. Fishman , Toshiko Mori , Landon S. Brown
CPC分类号： A47B37/00 , A47B13/003 , A47B21/06 , A47B2021/064 , A47B2037/005 , B01L9/02 , B01L2200/028
摘要： Modular laboratory workbenches and work surface accessories are provided. Modular laboratory workbenches may include a spine structure including multiple modules with core passageways for routing utilities. At least one spine structure module may include circuit breakers behind a panel for local electrical power control. The spine structure may include a top with angled faces that provide power outlets, gas terminals, and other utilities. Between angled faces, an accessory support structure may be provided that supports a backsplash in a center channel and provides accessory slots on both sides of the center channel to receive and support interchangeable accessories including monitor arms, tablet arms, gas turrets, supplemental lights, etc. Cantilever brackets of various heights may attach to the spine structure and support work surfaces that are translatable to provide access to the utilities provided on the angled faces of the spine structure.
摘要翻译： 提供模块化实验室工作台和工作台面附件。 模块化实验室工作台可以包括脊柱结构，其包括具有用于路由实用程序的核心通道的多个模块。 至少一个脊柱结构模块可以包括用于局部电力控制的面板后面的断路器。 脊柱结构可以包括顶部，其具有提供电源插座，气体端子和其它用途的成角度的面。 在倾斜面之间，可以提供支撑中心通道中的后挡板的附件支撑结构，并且在中心通道的两侧提供附件槽，以接收和支撑可互换的附件，包括监视器臂，平板臂，气炮塔，补充灯等 各种高度的悬臂支架可以附着在脊柱结构上并支撑可平移的工作表面，以提供对脊柱结构的倾斜面上提供的用途的访问。
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4.发明申请公开(公告)号：US20180118834A1
公开(公告)日：2018-05-03
申请号：US15543688
申请日：2016-01-15
申请人： Jennifer Brogdon , Hilmar Erhard Ebersbach , David Glass , Thomas Huber , Julia Jascur , Carl H. June , Jihyun Lee , Joan Mannick , Michael C. Milone , Leon Murphy , Avery D. Posey , Huijuan Song , Yongqiang Wang , Lai Wei , Qilong Wu , Qiumei Yang , Jiquan Zhang , Novartis Pharma AG , NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. , China Novartis Institutes for Biomedical Research , The Trustees of the University of Pennsylvania
发明人： Jennifer Brogdon , Hilmar Erhard Ebersbach , David Glass , Thomas Huber , Julia Jascur , Carl H. June , Jihyun Lee , Joan Mannick , Michael C. Milone , Leon Murphy , Avery D. Posey , Huijuan Song , Yongqiang Wang , Lai Wei , Qilong Wu , Qiumei Yang , Jiquan Zhang
IPC分类号： C07K16/28 , C07K14/705 , C07K14/725 , A61K35/17 , C07K16/30 , A61P35/00 , A61P35/02 , A61K48/00 , C12N15/86
CPC分类号： C07K16/2863 , A61K35/17 , A61K48/0058 , A61K2035/124 , A61P35/00 , A61P35/02 , C07K14/705 , C07K14/7051 , C07K14/70521 , C07K16/28 , C07K16/30 , C07K2319/00 , C07K2319/02 , C07K2319/03 , C12N15/86 , C12N2740/10043 , C12N2740/15043 , C12N2800/60
摘要： The invention provides compositions and methods for treating diseases associated with expression of a tumor antigen as described herein. The invention also relates to nucleic acids comprising a truncated PGK promoter operably linked to a chimeric antigen receptor (CAR) specific to a tumor antigen as described herein, vectors encoding the same, and recombinant T cells comprising the CARs of the present invention. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an antigen binding domain that binds to a tumor antigen as described herein.
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公开(公告)号：USD731699S1
公开(公告)日：2015-06-09
申请号：US29446568
申请日：2013-02-25
设计人： Mark C. Fishman , Toshiko Mori , Landon S. Brown
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公开(公告)号：USD717573S1
公开(公告)日：2014-11-18
申请号：US29446567
申请日：2013-02-25
设计人： Mark C. Fishman , Toshiko Mori , Landon S. Brown
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公开(公告)号：US20240262845A1
公开(公告)日：2024-08-08
申请号：US18099765
申请日：2023-01-20
发明人： Michael T. Taylor , Caleb R. Hoopes , Akash M. Sarkar , Nicholas J. Kuehl , Nicole L. Collins , Francisco J. Garcia , David T. Barkan , Glenna E. Meister , Taylor R. Bramhall , Chien-Hsiang Hsu , Michael D. Jones , Markus Schirle
IPC分类号： C07D495/04 , C07D213/89 , C07D401/12 , C07K1/113
CPC分类号： C07D495/04 , C07D213/89 , C07D401/12 , C07K1/113
摘要： Embodiments of the present disclosure generally relate to pyridinium salts, compositions thereof, and to methods of use. In an embodiment, a pyridinium salt described herein includes a group that is transferred to a tryptophan residue or moiety of a tryptophan-containing molecule. In another embodiment, a method for modifying a tryptophan residue is provided. The method includes forming a mixture comprising a pyridinium salt and a molecule containing a tryptophan moiety, and exposing the mixture to light to chemically modify the tryptophan moiety of the molecule.
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