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    Emission based fiber optic sensors for pH and carbon dioxide analysis
    3.
    发明授权
    Emission based fiber optic sensors for pH and carbon dioxide analysis 失效
    用于pH和二氧化碳分析的基于发射的光纤传感器

    公开(公告)号：US5280548A

    公开(公告)日：1994-01-18

    申请号：US3090

    申请日：1993-03-11

    申请人： Beauford W. Atwater ,  Olga Laksin

    发明人： Beauford W. Atwater ,  Olga Laksin

    IPC分类号： G01N21/64 ,  G01N21/77 ,  G01N21/80 ,  G01N31/22 ,  G02B6/00

    CPC分类号： G01N21/7703 ,  G01N21/6428 ,  G01N2021/6434 ,  G01N2021/772 ,  G01N2021/773 ,  G01N2021/7786 ,  G01N21/80 ,  G01N31/221

    摘要： The present invention is directed to a fiber optic sensor for analyzing pH which comprises (a) a fluorescence-based fiber optic sensor; and (b) a fluorescent dye-polymeric matrix in contact with the sensor, wherein the fluorescent dye is seminaphthorhodaflor-1-isothiocyanate, the polymer is a hydrogel selected from the group consisting of polyhydroxyethylmethacrylate, polyvinylpyrrolidone, cellulose, dextrans, and polysaccharides, and the dye is chemically bonded to the polymer. The present invention is also directed to a fiber optic sensor for analyzing carbon dioxide which comprises (a) a fluorescence-based fiber optic sensor; and (b) a fluorescent dye-polymeric-silicone elastomeric matrix in contact with the sensor, wherein the matrix comprises a fluorescent dye-polymeric premixture in a silicone elastomer, and the fluorescent dye is selected from the group consisting of seminaphthorhodaflor-1-carboxylate (SNARF-1C), seminaphthorhodaflor-1-isothiocyanate (SNARF-1C-ITC), seminaphthorhodaflor-1-dextran conjugate (SNARF-1C-Dex), 10-diethylamino seminaphthorhodaflor-1-carboxylate (SNARF-2C), and seminaphthorhodaflor-1-carboxylate 10-acetate (SNAFL-1C diacetate), the polymer is a hydrogel selected from the group consisting of polyhydroxyethylmethacrylate, polyvinylpyrrolidone, cellulose, dextrans, and polysaccharides, and the silicone elastomer is a polydimethyl siloxane selected from the group consisting of hydroxy, epoxy, and vinyl terminated polydimethyl siloxanes.

    摘要翻译： 本发明涉及一种用于分析pH的光纤传感器，其包括（a）基于荧光的光纤传感器; 和（b）与传感器接触的荧光染料 - 聚合物基质，其中所述荧光染料是半取代对苯二酚-1-异硫氰酸酯，所述聚合物是选自聚羟基乙基甲基丙烯酸酯，聚乙烯吡咯烷酮，纤维素，葡聚糖和多糖的水凝胶，以及 染料与聚合物化学键合。 本发明还涉及一种用于分析二氧化碳的光纤传感器，其包括（a）基于荧光的光纤传感器; 和（b）与所述传感器接触的荧光染料 - 聚合物硅酮弹性体基质，其中所述基质包含硅氧烷弹性体中的荧光染料 - 聚合物预混合物，并且所述荧光染料选自半庚四酮-1-羧酸 （SNARF-1C），semaphaphorhodaflor-1-isothiocyanate（SNARF-1C-ITC），seminaphthorhodaflor-1-葡聚糖缀合物（SNARF-1C-Dex），10-二乙基氨基seminaphthorhodaflor -1-羧酸盐（SNARF-2C）和seminaphthorhodaflor- （SNAFL-1C二乙酸酯），聚合物是选自聚羟乙基甲基丙烯酸酯，聚乙烯吡咯烷酮，纤维素，葡聚糖和多糖的水凝胶，硅氧烷弹性体是选自羟基的聚二甲基硅氧烷 ，环氧基和乙烯基封端的聚二甲基硅氧烷。

    Intra-aortic balloon catheter
    6.
    发明授权
    Intra-aortic balloon catheter 有权
    主动脉内气囊导管

    公开(公告)号：US6024693A

    公开(公告)日：2000-02-15

    申请号：US174279

    申请日：1998-10-16

    申请人： Robert Schock ,  Olga Laksin ,  Manuel Marques

    发明人： Robert Schock ,  Olga Laksin ,  Manuel Marques

    IPC分类号： A61F2/958 ,  A61L29/06 ,  A61L29/08 ,  A61L33/00 ,  A61M1/10 ,  A61N1/362

    CPC分类号： A61M25/10 ,  A61L29/06 ,  A61L29/085 ,  A61L33/0011 ,  A61M1/1072

    摘要： An improved intra-aortic balloon catheter with a balloon membrane, a tip, and a co-lumen extruded tube having an outer lumen and an inner lumen between the inner and outer surfaces of the co-lumen extruded tube. The portion of the co-lumen extruded tube that defines the inner lumen and which is disposed within the balloon membrane is made from polyimide, a lubricous material, to facilitate guide wire tracking. The polyimide inner tube portion demonstrates good kink resistance and flexural stiffness. In a first alternative embodiment of the invention the co-lumen tube comprises an outer tube with an inner tube embedded in the wall of said outer tube. In a second alternative embodiment of the invention a longitudinal signal pathway is provided.

    摘要翻译： 一种改进的主动脉内气囊导管，其具有球囊膜，尖端和共管腔挤压管，其在共管腔挤压管的内表面和外表面之间具有外腔和内腔。 限定内腔并且设置在球囊膜内的共管腔挤出管的部分由聚酰亚胺（润滑材料）制成，以便于导丝跟踪。 聚酰亚胺内管部分具有良好的耐扭结和弯曲刚度。 在本发明的第一替代实施例中，共管腔管包括外管，内管嵌在所述外管的壁中。 在本发明的第二替代实施例中，提供了纵向信号路径。