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公开(公告)号:US20090137063A1
公开(公告)日:2009-05-28
申请号:US12091344
申请日:2006-11-28
申请人: Karl Skold , Marcus Svensson , Per Andren , Per Svenningsson
发明人: Karl Skold , Marcus Svensson , Per Andren , Per Svenningsson
IPC分类号: G01N33/566 , G01N33/68 , G01N27/26 , B01D59/44
CPC分类号: G01N33/68 , G01N33/6842 , G01N33/6848 , G01N33/6851 , G01N33/96
摘要: The present invention relates to a method of determining the quality of a biological sample. A method according to the invention may be used to determine if a biological sample is suitable to use in a further biological assay demanding samples of good quality to render an accurate result. The method comprises detecting the presence of protein fragments in the biological sample by using appropriate means. The invention also relates to a kit for determining the quality of a biological sample.
摘要翻译: 本发明涉及一种确定生物样品质量的方法。 根据本发明的方法可用于确定生物样品是否适合用于进一步生物测定中,要求质量好的样品呈现准确的结果。 该方法包括通过使用适当的方法检测生物样品中蛋白质片段的存在。 本发明还涉及用于确定生物样品质量的试剂盒。
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公开(公告)号:US20050143408A1
公开(公告)日:2005-06-30
申请号:US11061881
申请日:2005-02-22
申请人: Hakan Wikstrom , Durk Dijkstra , Thomas Cremers , Per Andren , Sandrine Marchais , Ulrik Jurva
发明人: Hakan Wikstrom , Durk Dijkstra , Thomas Cremers , Per Andren , Sandrine Marchais , Ulrik Jurva
IPC分类号: A61K9/06 , A61K9/70 , A61K31/473 , A61K47/10 , A61K47/20 , A61K47/44 , A61P5/12 , A61P15/00 , A61P25/00 , A61P25/16 , A61P25/18 , A61P29/00 , C07D221/18 , C07D409/12
CPC分类号: A61K31/485 , A61K9/0014 , A61K9/0019 , A61K47/10 , A61K47/20 , A61K47/44 , C07D221/18 , C07D409/12
摘要: New aporphine derivatives are disclosed which have formula (I) and the physiologically acceptable salts thereof. Said derivatives may be used for the treatment of Parkinson's disease, hemicrania, restless legs syndrome (RLS), sexual dysfunction in men and women, hyperprolactemia and psychotic disorders, and/or evaluation of Parkinson's disease. Processes for the preparation of such derivatives are also disclosed.
摘要翻译: 公开了具有式(I)化合物及其生理上可接受的盐的新的阿朴肽衍生物。 所述衍生物可用于治疗帕金森病,血尿,不宁腿综合征(RLS),男性和女性性功能障碍,高血糖和精神病性障碍和/或帕金森氏病的评估。 还公开了制备这些衍生物的方法。
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公开(公告)号:US20070048792A1
公开(公告)日:2007-03-01
申请号:US11467820
申请日:2006-08-28
申请人: Karl Skold , Marcus Svensson , Goran Palmers , Per Andren
发明人: Karl Skold , Marcus Svensson , Goran Palmers , Per Andren
CPC分类号: G01N1/44 , C07K1/1136 , Y10T436/25
摘要: Methods and devices for preparing a biological sample for analysis are described. The biological sample from an organism has at least macromolecule having a primary structure that naturally degrades after the sample is removed from the organism. The method includes causing the biological sample to adopt a shape to permit rapid and uniform heating. The shaped sample is then rapidly and uniformly heated, thereby altering a secondary structure of the macromolecule while preserving its primary structure.
摘要翻译: 描述了用于制备用于分析的生物样品的方法和装置。 来自生物体的生物样品具有至少大分子,其具有在从生物体除去样品后自然降解的一级结构。 该方法包括使生物样品采用允许快速均匀加热的形状。 然后将成形的样品快速均匀地加热,从而改变大分子的二级结构,同时保持其主要结构。
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公开(公告)号:US20060168918A1
公开(公告)日:2006-08-03
申请号:US10537174
申请日:2003-12-02
申请人: Christina Naslund , Per Andren
发明人: Christina Naslund , Per Andren
CPC分类号: B68C1/02 , B68C1/16 , B68C2001/044
摘要: Saddle (10) for horseback riding, comprising a saddle base (30) that is anatomically adapted to the horseback, and a saddle seat (40), wherein that the saddle seat (40) is detachably arranged on the saddle base (30). The invention further relates to a saddle base (30) for a horseback saddle (10), comprising two pressure distributors (120) that are interconnected by a bridging arrangement (130) that provides clearance over the spinal region, wherein each pressure distributor (120) comprises a rigid section (170) and a peripheral flexing portion (180, 180a, 180b, 180c). Still further the invention relates to a saddle seat (40), a saddle pad (20) and a method of providing a saddle (10).
摘要翻译: 用于骑马的马鞍(10),包括在解剖学上适合于马背的鞍座(30)和鞍座(40),其中鞍座(40)可拆卸地布置在鞍座(30)上。 本发明还涉及一种用于马背鞍座(10)的马鞍座(30),其包括两个压力分配器(120),所述压力分配器通过提供脊柱区域之间的间隙的桥接装置(130)互连,其中每个压力分配器 )包括刚性部分(170)和周边弯曲部分(180,180a,180b,180c)。 本发明还涉及鞍座(40),鞍座(20)和提供鞍座(10)的方法。
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公开(公告)号:US20080119504A1
公开(公告)日:2008-05-22
申请号:US12021560
申请日:2008-01-29
申请人: Hakan WIKSTROM , Durk Dijkstra , Thomas Cremers , Per Andren , Sandrine Marchais , Ulrik Jurva
发明人: Hakan WIKSTROM , Durk Dijkstra , Thomas Cremers , Per Andren , Sandrine Marchais , Ulrik Jurva
IPC分类号: A61K31/485
CPC分类号: A61K31/485 , A61K9/0014 , A61K9/0019 , A61K47/10 , A61K47/20 , A61K47/44 , C07D221/18 , C07D409/12
摘要: New aporphine derivatives are disclosed which have formula (I) and the physiologically acceptable salts thereof. Said derivatives may be used for the treatment of Parkinson's disease, hemicrania, restless legs syndrome (RLS), sexual dysfunction in men and women, hyperprolactemia and psychotic disorders, and/or evaluation of Parkinson's disease. Processes for the preparation of such derivates are also disclosed.
摘要翻译: 公开了具有式(I)化合物及其生理上可接受的盐的新的阿朴肽衍生物。 所述衍生物可用于治疗帕金森病,血尿,不宁腿综合征(RLS),男性和女性性功能障碍,高血糖和精神病性障碍和/或帕金森氏病的评估。 还公开了制备这些衍生物的方法。
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