Solid-state colorimetric biosensors comprised of dendritic polymer networks
    1.
    发明申请
    Solid-state colorimetric biosensors comprised of dendritic polymer networks 有权
    固态比色生物传感器由树枝状聚合物网络组成

    公开(公告)号:US20050106572A1

    公开(公告)日:2005-05-19

    申请号:US10712739

    申请日:2003-11-13

    IPC分类号: C07H21/00 C12Q1/68

    CPC分类号: C07H21/00 Y10S436/805

    摘要: Solid-state colorimetric biosensors having sensory groups and interdendritic cross-linking segments of alternating conjugated double and triple bonds are prepared by intermolecular polymerization of diacetylene-functionalized dendritic polymer precursors. The polymerization process may be used to form solid films that are capable of indicating the presence of an analyte by a detectable change in color. The disclosed solid-state calorimetric biosensors may exhibit excellent stability at elevated temperatures and in the presence of organic solvents, and due to the dendritic architecture and high density of sensing functionality achieve high sensitivity to analytes.

    摘要翻译: 具有交联共轭双键和三键的感官基团和枝晶间交联链段的固态比色生物传感器通过二乙炔官能化的树枝状聚合物前体的分子间聚合制备。 聚合方法可以用于形成固体膜,其能够通过可检测的颜色变化来指示分析物的存在。 所公开的固态量热生物传感器在升高的温度和有机溶剂的存在下可表现出优异的稳定性,并且由于树突状结构和高密度的感测功能对分析物的高灵敏度。

    Nano-structured blood substitutes
    2.
    发明申请
    Nano-structured blood substitutes 有权
    纳米结构的血液代用品

    公开(公告)号:US20060147414A1

    公开(公告)日:2006-07-06

    申请号:US11324826

    申请日:2006-01-04

    IPC分类号: A61K31/74 A61K31/785

    CPC分类号: A61K31/74 A61K31/785

    摘要: An improved synthetic blood substitute which exhibits excellent long-term storage stability at both high and low temperatures is suitable for use in various biomedical and biotechnical applications, including resuscitation of trauma victims that have suffered massive hemorrhaging, and transfusions for human and veterinary surgical procedures. The artificial blood solution comprises an aqueous carrier, and a dendritic polymer that is capable of carrying oxygen dissolved in the aqueous carrier. The dendritic polymer comprises fluorocarbon moieties and hydrophilic moieties.

    摘要翻译: 在高温和低温下表现出优异的长期储存稳定性的改进的合成血液替代物适用于各种生物医学和生物技术应用,包括复苏大量出血的创伤受害者,以及用于人类和兽医外科手术的输血。 人造血液溶液包含水性载体和能够携带溶解在水性载体中的氧的树枝状聚合物。 树枝状聚合物包含氟碳部分和亲水部分。

    Beneficial agent delivery systems
    3.
    发明申请
    Beneficial agent delivery systems 有权
    有益代理人运送系统

    公开(公告)号:US20060018977A1

    公开(公告)日:2006-01-26

    申请号:US11185128

    申请日:2005-07-20

    IPC分类号: A01N59/04

    CPC分类号: A01N25/10 Y10S977/754

    摘要: An improved fragrance delivery system capable of providing controlled release of fragrance molecules in various consumer products is composed of a polymer having covalently bound fragrance moieties that are releasable in the form of fragrance molecules. Certain embodiments comprise globular polymer particles in which unbound fragrance molecules are occluded, absorbed and/or adsorbed. Certain other embodiments incorporate fragrance monomer units, which achieve reduced residuals upon complete release of the fragrance.

    摘要翻译: 能够提供各种消费品中香料分子的受控释放的改进的香料递送系统由具有共价结合的香味部分的聚合物组成,其可以以香料分子的形式释放。 某些实施方案包括球形聚合物颗粒,其中未结合的香料分子被封闭,吸收和/或吸附。 某些其他实施方案包括香料单体单元,其在完全释放香料时实现减少的残留。

    Cross-linked networks containing nanoscopic reinforcing domains
    4.
    发明申请
    Cross-linked networks containing nanoscopic reinforcing domains 有权
    包含纳米增强域的交联网络

    公开(公告)号:US20050277746A1

    公开(公告)日:2005-12-15

    申请号:US11206459

    申请日:2005-08-18

    摘要: Hyperbranched polymers having a plurality of at least two different types of functional groups are described. Specific embodiments include hyperbranched polymers having functional groups of a first type that are substantially uniformly distributed throughout the hyperbranched polymer molecule and a second type of functional group that is substantially uniformly distributed at the terminals of the hyperbranched polymer molecule. The hyperbranched polymers having different types of functional groups are synthesized by reacting one or more monomers having functional groups that are capable of reacting during a set of polymerization conditions to form a hyperbranched polymer, wherein at least one of the monomers contains latent functional groups that are not reactive during polymerization.

    摘要翻译: 描述了具有多个至少两种不同类型的官能团的超支化聚合物。 具体实施方案包括具有基本均匀分布在整个超支化聚合物分子中的第一类型的官能团的超支化聚合物和基本上均匀分布在超支化聚合物分子末端的第二类官能团。 具有不同类型官能团的超支化聚合物通过一种或多种具有能够在一组聚合条件下反应以形成超支化聚合物的官能团的单体反应来合成,其中至少一种单体含有潜在的官能团, 在聚合期间不反应。