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29 条记录 (耗时 0.014 秒)

    PERIFUSION DEVICE
    1.
    发明申请
    PERIFUSION DEVICE 有权
    PERIFUSION设备

    公开(公告)号：US20130040324A1

    公开(公告)日：2013-02-14

    申请号：US13595697

    申请日：2012-08-27

    申请人： Ramon E. Poo ,  Camillo Ricordi ,  Felipe Echeverri ,  Over Cabrera ,  Per-Olof Berggren

    发明人： Ramon E. Poo ,  Camillo Ricordi ,  Felipe Echeverri ,  Over Cabrera ,  Per-Olof Berggren

    IPC分类号： C12M1/36 ,  C12Q1/54 ,  G01N33/566 ,  C12Q1/02

    CPC分类号： C12M41/48 ,  B33Y80/00 ,  C12M23/12 ,  C12M23/40 ,  C12M23/42 ,  C12M41/00 ,  Y10T137/87249

    摘要： A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A manifold having a plurality of liquid inlets, control valves, and liquid outlets can be provided. A receptacle housing has a plurality of receptacles. A drive is connected to the receptacle housing for moving the receptacle housing. A programmable controller can be provided to control movement of the receptacle housing. The test liquid includes at least one stimuli for the cells. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.

    摘要翻译： 渗出装置包括用于细胞的至少一个样品容器，样品容器具有入口和出口。 容器通过入口接收测试液体，并通过出口排出液体。 可以提供具有多个液体入口，控制阀和液体出口的歧管。 插座壳体具有多个插座。 驱动器连接到插座壳体以移动插座壳体。 可以提供可编程控制器来控制插座壳体的运动。 测试液体包括用于细胞的至少一种刺激物。 分析收集在容器中的液体以确定细胞对刺激的反应。

    PERFUSION APPARATUS AND METHOD
    4.
    发明申请
    PERFUSION APPARATUS AND METHOD 审中-公开
    灌注装置和方法

    公开(公告)号：US20080286746A1

    公开(公告)日：2008-11-20

    申请号：US11750147

    申请日：2007-05-17

    申请人： Ramon E. Poo ,  Camillo Ricordi

    发明人： Ramon E. Poo ,  Camillo Ricordi

    IPC分类号： A01N1/00 ,  C12M1/00

    CPC分类号： A01N1/02 ,  A01N1/0247

    摘要： A perfusion apparatus for perfusing an organ includes a pump for pumping perfusion liquid though a perfusion liquid conduit, the conduit having an outlet. A pressure sensor senses the pressure of the perfusion liquid downstream of the pump and upstream of the outlet. A controller controls the output of the pump responsive to the pressure, so as to keep the pressure of the liquid reaching the organ substantially constant.

    摘要翻译： 用于灌注器官的灌注装置包括用于通过灌注液体导管泵送灌注液体的泵，所述导管具有出口。 压力传感器检测泵下游和出口上游的灌注液体的压力。 控制器响应于压力控制泵的输出，以便保持液体到达器官的压力基本上恒定。

    Apparatus and method for isolating cells from organs
    5.
    发明授权
    Apparatus and method for isolating cells from organs 有权
    从器官中分离细胞的装置和方法

    公开(公告)号：US06833270B2

    公开(公告)日：2004-12-21

    申请号：US09994445

    申请日：2001-11-27

    申请人： Ramon E. Poo ,  Camillo Ricordi

    发明人： Ramon E. Poo ,  Camillo Ricordi

    IPC分类号： C12N500

    CPC分类号： C12M45/02 ,  C12M45/09

    摘要： An apparatus and method for extracting cells from organs in which a digestion chamber includes at least one inlet and at least one outlet, and a separator for retaining the organ and permitting the cells and the physiologically compatible medium to exit the outlet. The digestion chamber can also includes at least one agitation member having an interior with at least one void. An agitation member for extracting cells from organs is also disclosed.

    摘要翻译： 一种用于从其中消化室包括至少一个入口和至少一个出口的器官中提取细胞的装置和方法，以及用于保持器官并允许细胞和生理学兼容介质离开出口的分离器。 消化室还可以包括具有至少一个空隙的内部的至少一个搅拌构件。 还公开了一种用于从器官中提取细胞的搅拌构件。

    Atrial lift retractor
    7.
    发明授权
    Atrial lift retractor 有权
    心房抬举器

    公开(公告)号：US08388525B2

    公开(公告)日：2013-03-05

    申请号：US12634344

    申请日：2009-12-09

    申请人： Ramon E. Poo ,  Joseph Lamelas

    发明人： Ramon E. Poo ,  Joseph Lamelas

    IPC分类号： A61B1/32

    CPC分类号： A61B17/02 ,  A61B17/0293 ,  A61B2017/00473 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/0237 ,  A61B2017/306 ,  A61B2217/005 ,  A61B2217/007

    摘要： A retractor includes a retractor support and an elongated retractor blade. The retractor blade has a first, closed position in which ends of the blade are positioned proximal to the support and a second, open position in which ends of the blade are positioned distal to the support. The retractor support has structure for engaging the retractor blade. A handle extends from the retractor support. A method of retracting tissue is also disclosed.

    摘要翻译： 牵开器包括牵开器支架和细长牵开器叶片。 牵开器叶片具有第一闭合位置，其中叶片的端部位于支撑件的近侧，以及第二打开位置，其中叶片的端部位于支撑件的远侧。 牵开器支架具有用于接合牵开器叶片的结构。 手柄从牵开器支架延伸。 还公开了一种缩回组织的方法。

    KNOT SETTER
    8.
    发明申请
    KNOT SETTER 审中-公开

    公开(公告)号：US20120203252A1

    公开(公告)日：2012-08-09

    申请号：US13447785

    申请日：2012-04-16

    申请人： Ramon E. Poo ,  Joseph Lamelas

    发明人： Ramon E. Poo ,  Joseph Lamelas

    IPC分类号： A61B17/04

    CPC分类号： A61B17/0469 ,  A61B17/0483 ,  A61B2017/2903

    摘要： A surgical knot setter includes an elongated shaft having a long axis and proximal and distal portions. A tip is provided at the distal end of the shaft. The tip has a loop with an interior loop opening and a gate opening for permitting ingress and egress of a suture into the loop opening. The loop is laterally offset from the long axis and distal to the distal end of the shaft, such that the loop is laterally and longitudinally offset from the distal end of the shaft. A closure is provided for selectively opening and closing the gate opening between open and closed positions to selectively permit or prevent the suture from passing through the gate opening. An actuator moves the closure between the open and closed positions. A method for tying suture knots is also disclosed.

    摘要翻译： 手术结装置包括具有长轴和近端和远端部分的细长轴。 尖端设置在轴的远端。 尖端具有环，其具有内部环开口和用于允许缝合线进入环开口的入口和门开口。 环路从轴线横向偏移并且远离轴的远端，使得环路从轴的远端侧向和纵向地偏移。 提供封闭件，用于选择性地打开和关闭打开和关闭位置之间的门开口，以选择性地允许或防止缝合线通过门开口。 致动器在打开位置和关闭位置之间移动闭合件。 还公开了一种用于捆扎缝合结的方法。

    Knot setter
    9.
    发明授权
    Knot setter 有权
    打结机

    公开(公告)号：US08162962B2

    公开(公告)日：2012-04-24

    申请号：US12711866

    申请日：2010-02-24

    申请人： Ramon E. Poo ,  Joseph Lamelas

    发明人： Ramon E. Poo ,  Joseph Lamelas

    IPC分类号： A61B17/04

    CPC分类号： A61B17/0469 ,  A61B17/0483 ,  A61B2017/2903

    摘要： A surgical knot setter includes an elongated shaft having a long axis and proximal and distal portions. A tip is provided at the distal end of the shaft. The tip has a loop with an interior loop opening and a gate opening for permitting ingress and egress of a suture into the loop opening. The loop is laterally offset from the long axis and distal to the distal end of the shaft, such that the loop is laterally and longitudinally offset from the distal end of the shaft. A closure is provided for selectively opening and closing the gate opening between open and closed positions to selectively permit or prevent the suture from passing through the gate opening. An actuator moves the closure between the open and closed positions. A method for tying suture knots is also disclosed.

    摘要翻译： 手术结装置包括具有长轴和近端和远端部分的细长轴。 尖端设置在轴的远端。 尖端具有环，其具有内部环开口和用于允许缝合线进入环开口的入口和门开口。 环路从轴线横向偏移并且远离轴的远端，使得环路从轴的远端侧向和纵向地偏移。 提供封闭件，用于选择性地打开和关闭打开和关闭位置之间的门开口，以选择性地允许或防止缝合线通过门开口。 致动器在打开位置和关闭位置之间移动闭合件。 还公开了一种用于捆扎缝合结的方法。

    Organ transportation device
    10.
    发明授权
    Organ transportation device 有权
    器官运输装置

    公开(公告)号：US07790437B2

    公开(公告)日：2010-09-07

    申请号：US11610913

    申请日：2006-12-14

    申请人： Ramon E. Poo ,  Camillo Ricordi

    发明人： Ramon E. Poo ,  Camillo Ricordi

    IPC分类号： A01N1/00 ,  A01N1/02 ,  C12M1/00 ,  C12M3/00

    CPC分类号： A01N1/02 ,  A01N1/0273

    摘要： An organ transportation device includes a fluid-tight organ container and structure within the organ container for engaging an organ within the organ container. A base assembly is provided, and structure for rotating the organ engaging structure and the organ relative to the base assembly. The base assembly can have a motor and a battery to provide for rotation of the organ container during shipping.

    摘要翻译： 器官输送装置包括在器官容器内的流体密封的器官容器和结构，用于与器官容器内的器官接合。 提供基座组件，以及用于相对于基座组件旋转器官接合结构和器官的结构。 基座组件可以具有马达和电池以在运输期间提供器官容器的旋转。