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公开(公告)号：US08926987B2
公开(公告)日：2015-01-06
申请号：US11282319
申请日：2005-11-17
IPC分类号： A61K39/12 , A61K39/23 , C12N15/86 , C07K14/005 , A61K39/00
CPC分类号： C12N15/86 , A61K39/21 , A61K2039/5256 , A61K2039/575 , C07K14/005 , C12N7/00 , C12N2710/10043 , C12N2710/10343 , C12N2710/16143 , C12N2740/15034 , C12N2740/15071 , C12N2740/16034 , C12N2740/16071 , C12N2740/16134 , C12N2740/16234 , C12N2740/16334
摘要： This invention provides improved replication-competent adenoviral vectors. The improved vectors have both a hybrid regulatory unit that provides for high level transgene expression. The vectors can be use, e.g., for therapeutic or prophylactic purposes.
摘要翻译： 本发明提供了改进的复制能力的腺病毒载体。 改进的载体具有提供高水平转基因表达的杂交调控单位。 可以使用载体，例如用于治疗或预防目的。
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公开(公告)号：US20060115456A1
公开(公告)日：2006-06-01
申请号：US11282319
申请日：2005-11-17
IPC分类号： A61K48/00 , C12N15/861 , C12N15/867
CPC分类号： C12N15/86 , A61K39/21 , A61K2039/5256 , A61K2039/575 , C07K14/005 , C12N7/00 , C12N2710/10043 , C12N2710/10343 , C12N2710/16143 , C12N2740/15034 , C12N2740/15071 , C12N2740/16034 , C12N2740/16071 , C12N2740/16134 , C12N2740/16234 , C12N2740/16334
摘要： This invention provides improved replication-competent adenoviral vectors. The improved vectors have both a hybrid regulatory unit that provides for high level transgene expression. The vectors can be use, e.g., for therapeutic or prophylactic purposes.
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