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公开(公告)号：US07009180B2
公开(公告)日：2006-03-07
申请号：US10319409
申请日：2002-12-12
申请人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
发明人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
IPC分类号： G01N21/35
CPC分类号： A61B5/1455 , A61B5/14532 , A61B5/14546 , A61B2562/0295 , G01N21/274 , G01N21/314 , G01N21/35 , G01N27/3271
摘要： A method uses spectroscopy to determine an analyte concentration in a sample. The method includes producing an absorbance spectrum of the sample. The method further includes shifting the absorbance spectrum to zero in a wavelength region. The method further includes subtracting a water or other substance contribution from the absorbance spectrum.
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2.发明授权Method of determining analyte concentration in a sample using infrared transmission data 有权使用红外线传输数据确定样品中分析物浓度的方法公开(公告)号：US07271912B2
公开(公告)日：2007-09-18
申请号：US10825085
申请日：2004-04-15
申请人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
发明人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
CPC分类号： A61B5/14546 , A61B5/14532 , G01N21/03 , G01N21/314 , G01N21/35
摘要： A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance.
摘要翻译： 一种方法确定样品中的分析物浓度。 样品包括分析物和物质。 该方法包括提供样品的吸收数据。 该方法还包括提供该物质的参考吸收数据。 该方法还包括计算吸收数据的物质贡献。 该方法还包括从吸收数据中减去物质贡献，由此提供基本上不含该物质贡献的校正吸收数据。
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公开(公告)号：US07050157B2
公开(公告)日：2006-05-23
申请号：US10200384
申请日：2002-07-19
申请人： James R. Braig , Peter Rule , Robert D. Gaffney , Philip C. Hartstein , Julian M. Cortella , Kenneth I. Li , Bernhard B. Sterling , Peng Zheng , W. Dale Hall , Kenneth G. Witte , Mark D. Agostino , Daniel S. Goldberger
发明人： James R. Braig , Peter Rule , Robert D. Gaffney , Philip C. Hartstein , Julian M. Cortella , Kenneth I. Li , Bernhard B. Sterling , Peng Zheng , W. Dale Hall , Kenneth G. Witte , Mark D. Agostino , Daniel S. Goldberger
IPC分类号： G01N33/48
CPC分类号： A61B5/1455 , A61B5/01 , A61B5/14532 , A61B5/150022 , A61B5/150061 , A61B5/150213 , A61B5/150274 , A61B5/150358 , A61B5/150412 , A61B5/150458 , A61B5/150755 , A61B5/15087 , A61B5/151 , A61B5/157 , A61B5/6826 , A61B5/6838 , A61B2562/0295 , A61B2562/12 , G01N21/35
摘要： A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.
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公开(公告)号：US06862534B2
公开(公告)日：2005-03-01
申请号：US10366540
申请日：2003-02-12
申请人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
发明人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
CPC分类号： A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B2562/0295 , G01N21/274 , G01N21/314 , G01N21/35 , G01N27/3271
摘要： A method determines an analyte concentration in a sample including the analyte and a substance. The method includes providing an absorption spectrum of the sample. The absorption spectrum has an absorption baseline. The method further includes shifting the absorption spectrum so that the absorption baseline approximately equals a selected absorption value in a selected absorption wavelength range. The method further includes subtracting a substance contribution from the absorption spectrum. Thus, the method provides a corrected absorption spectrum substantially free of a contribution from the substance.
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5.发明申请METHOD OF DETERMINING ANALYTE CONCENTRATION IN A SAMPLE USING INFRARED TRANSMISSION DATA 有权使用红外传输数据确定样品中分析物浓度的方法公开(公告)号：US20080212071A1
公开(公告)日：2008-09-04
申请号：US11841878
申请日：2007-08-20
申请人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philp C. Hartstein , Robert D. Gaffney
发明人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philp C. Hartstein , Robert D. Gaffney
IPC分类号： G01N21/00
CPC分类号： A61B5/14546 , A61B5/14532 , G01N21/03 , G01N21/314 , G01N21/35
摘要： A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance.
摘要翻译： 一种方法确定样品中的分析物浓度。 样品包括分析物和物质。 该方法包括提供样品的吸收数据。 该方法还包括提供该物质的参考吸收数据。 该方法还包括计算吸收数据的物质贡献。 该方法还包括从吸收数据中减去物质贡献，由此提供基本上不含该物质贡献的校正吸收数据。
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6.发明授权Method of determining analyte concentration in a sample using infrared transmission data 有权使用红外线传输数据确定样品中分析物浓度的方法公开(公告)号：US07593108B2
公开(公告)日：2009-09-22
申请号：US11841878
申请日：2007-08-20
申请人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
发明人： Bernhard B. Sterling , James R. Braig , Daniel S. Goldberger , Philip C. Hartstein , Robert D. Gaffney
CPC分类号： A61B5/14546 , A61B5/14532 , G01N21/03 , G01N21/314 , G01N21/35
摘要： A method determines an analyte concentration in a sample. The sample includes the analyte and a substance. The method includes providing absorption data of the sample. The method further includes providing reference absorption data of the substance. The method further includes calculating a substance contribution of the absorption data. The method further includes subtracting the substance contribution from the absorption data, thereby providing corrected absorption data substantially free of a contribution from the substance.
摘要翻译： 一种方法确定样品中的分析物浓度。 样品包括分析物和物质。 该方法包括提供样品的吸收数据。 该方法还包括提供该物质的参考吸收数据。 该方法还包括计算吸收数据的物质贡献。 该方法还包括从吸收数据中减去物质贡献，由此提供基本上不含该物质贡献的校正吸收数据。
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公开(公告)号：US06958809B2
公开(公告)日：2005-10-25
申请号：US10055875
申请日：2002-01-21
申请人： Bernhard B. Sterling , Philip C. Hartstein , Ken I. Li , Mark D. Agostino , David C. Klonoff , Robert D. Gaffney , Jennifer H. Gable , Ken G. Witte , Mike A. Munrow , Daniel S. Goldberger , Julian M. Cortella , James R. Braig , Peter Rule
发明人： Bernhard B. Sterling , Philip C. Hartstein , Ken I. Li , Mark D. Agostino , David C. Klonoff , Robert D. Gaffney , Jennifer H. Gable , Ken G. Witte , Mike A. Munrow , Daniel S. Goldberger , Julian M. Cortella , James R. Braig , Peter Rule
CPC分类号： A61B5/01 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150458 , A61B5/150503 , A61B5/15087 , A61B5/15107 , A61B5/15136 , A61B5/1514 , A61B5/15186 , A61B5/157 , A61B5/6826 , A61B5/6838 , A61B2562/0295 , A61B2562/12 , G01N21/35
摘要： A reagentless whole-blood analyte detection system that is capable of being deployed near a patient has a source capable of emitting a beam of radiation that includes a spectral band. The whole-blood system also has a detector in an optical path of the beam. The whole-blood system also has a housing that is configured to house the source and the detector. The whole-blood system also has a sample element that is situated in the optical path of the beam. The sample element has a sample cell and a sample cell wall that does not eliminate transmittance of the beam of radiation in the spectral band.
摘要翻译： 能够在患者附近部署的无试剂全血分析物检测系统具有能够发射包括光谱带的辐射束的源。 全血系统还具有光束的光路中的检测器。 全血系统还具有容纳源和检测器的壳体。 全血系统还具有位于束的光路中的样品元件。 样品元件具有不消除光谱带中的辐射束的透射率的样品池和样品池壁。
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