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    Systems and methods for determining physiological parameters using measured analyte values
    3.
    发明授权
    Systems and methods for determining physiological parameters using measured analyte values 有权
    使用测量的分析物值确定生理参数的系统和方法

    公开(公告)号：US08412293B2

    公开(公告)日：2013-04-02

    申请号：US12174501

    申请日：2008-07-16

    Applicant: Peter Rule

    Inventor： Peter Rule

    IPC: A61K5/00

    CPC classification number: A61B5/150992 ,  A61B5/029 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150267 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150862 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/412 ,  A61M2005/1404 ,  G01N21/359 ,  G06F19/00

    Abstract: Systems and methods for determining a physiological parameter in a patient are provided. In certain embodiments, a system can include an analyte detection system configured to measure first analyte data in a fluid sample received from a patient, a medical sensor configured to measure second analyte data in the patient, and a processor configured to receive the first analyte data and the second analyte data and to determine a physiological parameter based at least in part on the first analyte data and the second analyte data. In certain such embodiments, the medical sensor may be a pulse oximeter, and the physiological parameter may include a cardiovascular parameter including, for example, cardiac output.

    Abstract translation: 提供了用于确定患者生理参数的系统和方法。 在某些实施例中，系统可以包括分析物检测系统，其被配置为测量从患者接收的流体样品中的第一分析物数据，被配置为测量患者中的第二分析物数据的医学传感器，以及被配置为接收第一分析物数据 和第二分析物数据，并且至少部分地基于第一分析物数据和第二分析物数据来确定生理参数。 在某些这样的实施例中，医疗传感器可以是脉搏血氧计，并且生理参数可以包括包括例如心输出量的心血管参数。

    Systems And Methods For Determining Physiological Parameters Using Measured Analyte Values
    8.
    发明申请
    Systems And Methods For Determining Physiological Parameters Using Measured Analyte Values 有权
    使用测量的分析物值确定生理参数的系统和方法

    公开(公告)号：US20090043171A1

    公开(公告)日：2009-02-12

    申请号：US12174501

    申请日：2008-07-16

    Applicant: Peter Rule

    Inventor： Peter Rule

    IPC: A61B5/00

    CPC classification number: A61B5/150992 ,  A61B5/029 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14551 ,  A61B5/14557 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150267 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150862 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/412 ,  A61M2005/1404 ,  G01N21/359 ,  G06F19/00

    Abstract: Systems and methods for determining a physiological parameter in a patient are provided. In certain embodiments, a system can include an analyte detection system configured to measure first analyte data in a fluid sample received from a patient, a medical sensor configured to measure second analyte data in the patient, and a processor configured to receive the first analyte data and the second analyte data and to determine a physiological parameter based at least in part on the first analyte data and the second analyte data. In certain such embodiments, the medical sensor may be a pulse oximeter, and the physiological parameter may include a cardiovascular parameter including, for example, cardiac output.

    Abstract translation: 提供了用于确定患者生理参数的系统和方法。 在某些实施例中，系统可以包括分析物检测系统，其被配置为测量从患者接收的流体样品中的第一分析物数据，被配置为测量患者中的第二分析物数据的医学传感器，以及被配置为接收第一分析物数据 和第二分析物数据，并且至少部分地基于第一分析物数据和第二分析物数据来确定生理参数。 在某些这样的实施例中，医疗传感器可以是脉搏血氧计，并且生理参数可以包括包括例如心输出量的心血管参数。

    DUAL MEASUREMENT ANALYTE DETECTION SYSTEM
    9.
    发明申请
    DUAL MEASUREMENT ANALYTE DETECTION SYSTEM 审中-公开
    双测量分析仪检测系统

    公开(公告)号：US20080268486A1

    公开(公告)日：2008-10-30

    申请号：US12171205

    申请日：2008-07-10

    Applicant: James R. Braig ,  Peter Rule ,  Kenneth G. Witte ,  Philip C. Hartstein ,  Bernhard B. Sterling

    Inventor： James R. Braig ,  Peter Rule ,  Kenneth G. Witte ,  Philip C. Hartstein ,  Bernhard B. Sterling

    IPC: C12Q1/54 ,  C12M1/00

    CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/14546

    Abstract: An analyte detection system is configured to measure concentrations of at least first and second analytes in a single material sample supported by a sample element. The measurement of a second analyte can be conditioned on a quantitative or qualitative result of the first measurement. In one embodiment, the first analyte is glucose and the second analyte is a ketone. According to such an embodiment the ketone is measured if the result of the glucose measurement exceeds a previously-specified value or falls outside of a previously-specified range.

    Abstract translation: 分析物检测系统被配置为测量由样品元素支持的单个材料样品中的至少第一和第二分析物的浓度。 第二分析物的测量可以对第一次测量的定量或定性结果进行调节。 在一个实施方案中，第一分析物是葡萄糖，第二分析物是酮。 根据这样的实施方案，如果葡萄糖测量结果超过预先规定的值或者超出预先规定的范围，则测量酮。

    Near-patient module for analyte detection system
    10.
    发明申请
    Near-patient module for analyte detection system 审中-公开
    用于分析物检测系统的近距离模块

    公开(公告)号：US20070082342A1

    公开(公告)日：2007-04-12

    申请号：US11316681

    申请日：2005-12-21

    Applicant: James Braig ,  Kenneth Witte ,  Mark Wechsler ,  Peter Rule ,  Richard Keenan

    Inventor： James Braig ,  Kenneth Witte ,  Mark Wechsler ,  Peter Rule ,  Richard Keenan

    IPC: C12Q1/68 ,  C12M1/34

    CPC classification number: A61B5/14546 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150755 ,  A61B5/150862 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61B5/4839 ,  A61M5/14212 ,  A61M2230/20 ,  G01N35/1095

    Abstract: In certain embodiments, an apparatus for analyzing the composition of bodily fluid includes a first fluid passageway having a patient end which is configured to provide fluid communication with a bodily fluid within a patient. The apparatus further includes at least one pump coupled to the first fluid passageway. The at least one pump has an infusion mode in which the pump is operable to deliver infusion fluid to the patient through the patient end, and a sample draw mode in which the pump is operable to draw a sample of the bodily fluid from the patient through the patient end. The apparatus further includes an analyte detection system accessible via the first fluid passageway such that the analyte detection system can receive at least one component of the drawn sample of bodily fluid and determine a concentration of at least one analyte. The analyte detection system is spaced from the patient end of the first fluid passageway. The apparatus further includes a fluid sensor located at or near the patient end of the first fluid passageway and spaced from the analyte detection system. The fluid sensor is configured to sense a property of a fluid within the first fluid passageway.

    Abstract translation: 在某些实施例中，用于分析体液组成的装置包括具有患者端的第一流体通道，该患者端构造成提供与患者体内的体液的流体连通。 该装置还包括耦合到第一流体通道的至少一个泵。 所述至少一个泵具有输注模式，其中所述泵可操作以通过患者端向患者输送输注流体，以及抽样模式，其中所述泵可操作以从患者抽取体液样本通过 病人结束 该装置还包括可经由第一流体通道接近的分析物检测系统，使得分析物检测系统可以接收抽取的体液样本的至少一个组分并确定至少一种分析物的浓度。 分析物检测系统与第一流体通道的患者端隔开。 该装置还包括位于第一流体通道的患者端处或附近的流体传感器，并与分析物检测系统间隔开。 流体传感器构造成感测第一流体通道内的流体的性质。

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