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    Drug eluting folded stent and stent delivery system
    3.
    发明授权
    Drug eluting folded stent and stent delivery system 有权

    公开(公告)号：US09615948B2

    公开(公告)日：2017-04-11

    申请号：US12767099

    申请日：2010-04-26

    申请人： Robert Melder

    发明人： Robert Melder

    IPC分类号： A61F2/84 ,  A61F2/91 ,  A61F2/958

    CPC分类号： A61F2/91 ,  A61F2/958 ,  A61F2230/0054 ,  A61F2250/0068 ,  Y10T29/49982

    摘要： The drug eluting folded stent and a stent delivery system, which includes a stent having a plurality of struts interconnected to form a tubular body. At least one of the struts includes a U-shaped strut having in cross-section a first leg, a second leg, and a closed end connecting the first leg and the second leg, wherein the first leg, the second leg, and the closed end define a recess having a drug release opening opposite the closed end; and a drug coating disposed on the first leg, the second leg, and the closed end within the recess. The drug release opening is sized to release a drug from the drug coating at a predetermined drug elution rate.

    Apparatus and Methods for Loading a Drug Eluting Medical Device
    4.
    发明申请
    Apparatus and Methods for Loading a Drug Eluting Medical Device 有权

    公开(公告)号：US20120067454A1

    公开(公告)日：2012-03-22

    申请号：US12884501

    申请日：2010-09-17

    申请人： Robert Melder

    发明人： Robert Melder

    IPC分类号： B65B3/04

    CPC分类号： A61F2/915 ,  A61F2/88 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2240/001 ,  A61F2250/0067 ,  A61F2250/0068 ,  A61L31/16 ,  A61L2300/00 ,  A61L2420/02

    摘要： Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

    Apparatus and methods for loading a drug eluting medical device
    5.
    发明授权
    Apparatus and methods for loading a drug eluting medical device 有权

    公开(公告)号：US08678046B2

    公开(公告)日：2014-03-25

    申请号：US12884501

    申请日：2010-09-17

    申请人： Robert Melder ,  Barry Wohl

    发明人： Robert Melder ,  Barry Wohl

    IPC分类号： B65B3/04

    CPC分类号： A61F2/915 ,  A61F2/88 ,  A61F2002/91575 ,  A61F2210/0004 ,  A61F2240/001 ,  A61F2250/0067 ,  A61F2250/0068 ,  A61L31/16 ,  A61L2300/00 ,  A61L2420/02

    摘要： Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

    Method of Treating Erectile Dysfunction
    6.
    发明申请
    Method of Treating Erectile Dysfunction 审中-公开
    治疗勃起功能障碍的方法

    公开(公告)号：US20100261737A1

    公开(公告)日：2010-10-14

    申请号：US12421768

    申请日：2009-04-10

    申请人： Garrett Pilcher ,  Mark J. Dolan ,  Robert Melder ,  Christopher Bingham

    发明人： Garrett Pilcher ,  Mark J. Dolan ,  Robert Melder ,  Christopher Bingham

    IPC分类号： A61K31/519

    CPC分类号： A61K31/519

    摘要： A combined therapy for treatment of a patient having erectile dysfunction at least in part caused by vascular disease within a pelvic vessel is disclosed that includes placement of a stent within a stenosed region of the pelvic vessel in conjunction with the administration of a drug for treatment of erectile dysfunction.

    摘要翻译： 公开了用于治疗至少部分由骨盆内血管疾病引起的勃起功能障碍的患者的联合疗法，其包括将支架放置在骨盆容器的狭窄区域内，同时施用用于治疗 勃起功能障碍。

    Textured medical devices
    9.
    发明授权
    Textured medical devices 有权
    纹理医疗器械

    公开(公告)号：US07753962B2

    公开(公告)日：2010-07-13

    申请号：US11668708

    申请日：2007-01-30

    申请人： Robert Melder

    发明人： Robert Melder

    IPC分类号： A61F2/28 ,  A61F2/06

    CPC分类号： A61L27/28 ,  A61L27/50 ,  A61L29/08 ,  A61L29/14 ,  A61L31/08 ,  A61L31/14 ,  A61L2400/18

    摘要： Disclosed are medical devices having textured surfaces and biocompatible coatings disposed thereon. The textured surfaces allow for durable coatings to be applied to the medical device without a previous pre-coating having been applied. The biocompatible coating can further comprise a bioactive agent.

    摘要翻译： 公开了具有纹理表面和设置在其上的生物相容性涂层的医疗装置。 纹理表面允许将耐用涂层施加到医疗装置，而不施加先前的预涂层。 生物相容性涂层还可包含生物活性剂。