公开(公告)号：US09649036B2

公开(公告)日：2017-05-16

申请号：US13096904

申请日：2011-04-28

申请人： Rodrigo Teixeira

发明人： Rodrigo Teixeira

IPC分类号： A61B5/0205 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/0402

CPC分类号： A61B5/0205 ,  A61B5/0402 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7278

摘要： A probabilistic digital signal processor is described. Initial probability distribution functions are input to a dynamic state-space model, which operates on state and/or model probability distribution functions to generate a prior probability distribution function, which is input to a probabilistic updater. The probabilistic updater integrates sensor data with the prior to generate a posterior probability distribution function passed (1) to a probabilistic sampler, which estimates one or more parameters using the posterior, which is output or re-sampled in an iterative algorithm or (2) iteratively to the dynamic state-space model. For example, the probabilistic processor operates using a physical model on data from a mechanical system or a medical meter or instrument, such as an electrocardiogram. Output of the physical model yields an enhanced output of the original data, an output to a second physical parameter not output by the medical meter, or a prediction, such as an arrhythmia warning.

公开(公告)号：US20120022336A1

公开(公告)日：2012-01-26

申请号：US13181247

申请日：2011-07-12

申请人： Rodrigo Teixeira

发明人： Rodrigo Teixeira

IPC分类号： A61B5/00

CPC分类号： A61B5/0205 ,  A61B5/0402 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7242 ,  A61B5/725 ,  A61B5/7264

摘要： A probabilistic digital signal processor using data from multiple instruments is described. In one example, a digital signal processor is integrated into a biomedical device. The processor is configured to: use a dynamic state-space model configured with a physiological model of a body system to provide a prior probability distribution function; receive sensor data input from at least two data sources; and iteratively use a probabilistic updater to integrate the sensor data as a fused data set and generate a posterior probability distribution function using all of: (1) the fused data set; (2) an application of Bayesian probability; and (3) the prior probability distribution function. The processor further generates an output of a biomedical state using the posterior probability function.

摘要翻译： 描述了使用来自多个仪器的数据的概率数字信号处理器。 在一个示例中，将数字信号处理器集成到生物医学装置中。 处理器被配置为：使用配置有身体系统的生理模型的动态状态空间模型来提供先验概率分布函数; 从至少两个数据源接收传感器数据输入; 并迭代地使用概率更新器将传感器数据作为融合数据集进行集成，并使用以下所有方法生成后验概率分布函数：（1）融合数据集; （2）贝叶斯概率的应用; 和（3）先验概率分布函数。 处理器使用后验概率函数进一步产生生物医学状态的输出。

公开(公告)号：US08450111B2

公开(公告)日：2013-05-28

申请号：US12970484

申请日：2010-12-16

申请人： Roberto Di Salvo ,  Alton Reich ,  H. Waite H. Dykes, Jr. ,  Rodrigo Teixeira

发明人： Roberto Di Salvo ,  Alton Reich ,  H. Waite H. Dykes, Jr. ,  Rodrigo Teixeira

IPC分类号： C12N1/12 ,  C12N5/00 ,  C12N5/02 ,  C12P1/00 ,  C12P39/00

CPC分类号： C07H1/08 ,  C08H8/00 ,  C10G2300/1014 ,  C10L1/02 ,  C11B1/02 ,  C11B1/10 ,  C12M47/06 ,  C12M47/10 ,  C12P7/6463 ,  Y02P30/20

摘要： A one-step process for the lysis of microalgae cell walls and separation of the cellular lipids for use in biofuel production by utilizing a hydrophilic ionic liquid, 1-butyl-3-methylimidazolium. The hydrophilic ionic liquid both lyses the microalgae cell walls and forms two immiscible layers, one of which consists of the lipid contents of the lysed cells. After mixture of the hydrophilic ionic liquid with a suspension of microalgae cells, gravity causes a hydrophobic lipid phase to move to a top phase where it is removed from the mixture and purified. The hydrophilic ionic liquid is recycled to lyse new microalgae suspensions.

摘要翻译： 通过使用亲水性离子液体1-丁基-3-甲基咪唑，微藻细胞壁的裂解和用于生物燃料生产的细胞脂质的分离的一步法。 亲水离子液体两者都溶解微藻细胞壁并形成两个不混溶层，其中之一由裂解细胞的脂质含量组成。 在将亲水离子液体与微藻细胞的悬浮液混合后，重力使疏水性脂质相移动至顶部相，并将其从混合物中除去并纯化。 亲水离子液体被再循环以溶解新的微藻悬浮液。

公开(公告)号：US20110076748A1

公开(公告)日：2011-03-31

申请号：US12970512

申请日：2010-12-16

申请人： Roberto Di Salvo ,  Alton Reich ,  H. Walte H. Dykes, JR. ,  Rodrigo Teixeira

发明人： Roberto Di Salvo ,  Alton Reich ,  H. Walte H. Dykes, JR. ,  Rodrigo Teixeira

IPC分类号： C12N1/12

CPC分类号： C12N1/06 ,  C12M47/06 ,  C12M47/10 ,  Y02W10/37

摘要： The invention relates to use of an active ionic liquid to dissolve algae cell walls. The ionic liquid is used to, in an energy efficient manner, dissolve and/or lyse an algae cell walls, which releases algae constituents used in the creation of energy, fuel, and/or cosmetic components. The ionic liquids include ionic salts having multiple charge centers, low, very low, and ultra low melting point ionic liquids, and combinations of ionic liquids.An algae treatment system is described, which processes wet algae in a lysing reactor, separates out algae constituent products, and optionally recovers the ionic liquid in an energy efficient manner.

摘要翻译： 本发明涉及使用活性离子液体来溶解藻类细胞壁。 离子液体以能量有效的方式被用于溶解和/或溶解藻类细胞壁，其释放用于产生能量，燃料和/或化妆品组分的藻类成分。 离子液体包括具有多个电荷中心，低，非常低和超低熔点离子液体的离子盐，以及离子液体的组合。描述了一种在裂解反应器中处理湿藻类的藻类处理系统，将藻类成分 产品，并且以能量有效的方式任选地回收离子液体。

公开(公告)号：US20120022350A1

公开(公告)日：2012-01-26

申请号：US13181027

申请日：2011-07-12

申请人： Rodrigo Teixeira

发明人： Rodrigo Teixeira

IPC分类号： A61B5/0205 ,  G06F17/18

CPC分类号： A61B5/0205 ,  A61B5/0402 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7278

摘要： A probabilistic digital signal processor using data from multiple instruments is described. Initial probability distribution functions are input to a dynamic state-space model, which operates on state and/or model probability distribution functions to generate a prior probability distribution function, which is input to a probabilistic updater. The probabilistic updater integrates sensor data from multiple instruments with the prior to generate a posterior probability distribution function passed (1) to a probabilistic sampler, which estimates one or more parameters using the posterior, which is output or re-sampled in an iterative algorithm or (2) iteratively to the dynamic state-space model. For example, the probabilistic processor operates on fused data using a physical model, where the data originates from a mechanical system or a medical meter or instrument, such as an electrocardiogram or pulse oximeter to generate new parameter information and/or enhanced parameter information.

摘要翻译： 描述了使用来自多个仪器的数据的概率数字信号处理器。 初始概率分布函数被输入到动态状态空间模型，该模型对状态和/或模型概率分布函数进行操作，以生成输入到概率更新器的先验概率分布函数。 概率更新器将来自多个仪器的传感器数据与先前的传感器数据进行整合，以生成经过（1）的后验概率分布函数到概率采样器，该概率采样器使用后验估计一个或多个参数，后者以迭代算法输出或重新采样， （2）迭代到动态状态空间模型。 例如，概率处理器使用物理模型对融合数据进行操作，其中数据源自机械系统或诸如心电图或脉搏血氧计的医疗仪表或仪器，以产生新的参数信息和/或增强的参数信息。

公开(公告)号：US20110130551A1

公开(公告)日：2011-06-02

申请号：US12970484

申请日：2010-12-16

申请人： Roberto Di Salvo ,  Alton Reich ,  H. Waite H. Dykes ,  Rodrigo Teixeira

发明人： Roberto Di Salvo ,  Alton Reich ,  H. Waite H. Dykes ,  Rodrigo Teixeira

IPC分类号： C11B1/00 ,  C07K1/14 ,  C07H1/08 ,  C08B1/00 ,  C12N1/12

CPC分类号： C07H1/08 ,  C08H8/00 ,  C10G2300/1014 ,  C10L1/02 ,  C11B1/02 ,  C11B1/10 ,  C12M47/06 ,  C12M47/10 ,  C12P7/6463 ,  Y02P30/20

摘要： A one-step process for the lysis of microalgae cell walls and separation of the cellular lipids for use in biofuel production by utilizing a hydrophilic ionic liquid, 1-butyl-3-methylimidazolium. The hydrophilic ionic liquid both lyses the microalgae cell walls and forms two immiscible layers, one of which consists of the lipid contents of the lysed cells. After mixture of the hydrophilic ionic liquid with a suspension of microalgae cells, gravity causes a hydrophobic lipid phase to move to a top phase where it is removed from the mixture and purified. The hydrophilic ionic liquid is recycled to lyse new microalgae suspensions.

摘要翻译： 通过使用亲水性离子液体1-丁基-3-甲基咪唑，微藻细胞壁的裂解和用于生物燃料生产的细胞脂质的分离的一步法。 亲水离子液体两者都溶解微藻细胞壁并形成两个不混溶层，其中之一由裂解细胞的脂质含量组成。 在将亲水离子液体与微藻细胞的悬浮液混合后，重力使疏水性脂质相移动至顶部相，并将其从混合物中除去并纯化。 亲水离子液体被再循环以溶解新的微藻悬浮液。

公开(公告)号：US20120022844A1

公开(公告)日：2012-01-26

申请号：US13181140

申请日：2011-07-12

申请人： Rodrigo Teixeira

发明人： Rodrigo Teixeira

IPC分类号： G06G7/60 ,  G06G7/48

CPC分类号： A61B5/0205 ,  A61B5/0402 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7214 ,  G06K9/00496 ,  G06K9/6289

摘要： A probabilistic digital signal processor using data from multiple instruments is described. In one example, an analyzer is configured to: receive discrete first and second input data, related to a first and second sub-system of the system, from a first and second instrument, respectively. A system processor is used to fuse the first and second input data into fused data. The system processor optionally includes: (1) a probabilistic processor configured to convert the fused data into at least two probability distribution functions and (2) a dynamic state-space model, the dynamic state-space model including at least one probabilistic model configured to operate on the at least two probability distribution functions. The system processor iteratively circulates the at least two probability distribution functions in the dynamic state-space model in synchronization with receipt of updated input data, processes the probability distribution functions, and generates an output related to the state of the system.

摘要翻译： 描述了使用来自多个仪器的数据的概率数字信号处理器。 在一个示例中，分析器被配置为：分别从第一和第二仪器接收与系统的第一和第二子系统相关的离散的第一和第二输入数据。 系统处理器用于将第一和第二输入数据融合成融合数据。 所述系统处理器可选地包括：（1）概率处理器，被配置为将所述融合数据转换成至少两个概率分布函数，以及（2）动态状态空间模型，所述动态状态空间模型包括至少一个概率模型， 对至少两个概率分布函数进行操作。 与动态状态空间模型中的至少两个概率分布函数迭代地循环地传递更新的输入数据的接收，处理概率分布函数，并产生与系统的状态相关的输出。

公开(公告)号：US20120022384A1

公开(公告)日：2012-01-26

申请号：US13096904

申请日：2011-04-28

申请人： Rodrigo Teixeira

发明人： Rodrigo Teixeira

IPC分类号： A61B5/0402 ,  A61B5/02

CPC分类号： A61B5/0205 ,  A61B5/0402 ,  A61B5/14551 ,  A61B5/7203 ,  A61B5/7214 ,  A61B5/7278

摘要： A probabilistic digital signal processor is described. Initial probability distribution functions are input to a dynamic state-space model, which operates on state and/or model probability distribution functions to generate a prior probability distribution function, which is input to a probabilistic updater. The probabilistic updater integrates sensor data with the prior to generate a posterior probability distribution function passed (1) to a probabilistic sampler, which estimates one or more parameters using the posterior, which is output or re-sampled in an iterative algorithm or (2) iteratively to the dynamic state-space model. For example, the probabilistic processor operates using a physical model on data from a mechanical system or a medical meter or instrument, such as an electrocardiogram. Output of the physical model yields an enhanced output of the original data, an output to a second physical parameter not output by the medical meter, or a prediction, such as an arrhythmia warning.

摘要翻译： 描述概率数字信号处理器。 初始概率分布函数被输入到动态状态空间模型，该模型对状态和/或模型概率分布函数进行操作，以生成输入到概率更新器的先验概率分布函数。 概率更新器将传感器数据与先前集成，生成经过（1）的后验概率分布函数到概率采样器，该概率采样器使用后验估计一个或多个参数，后者以迭代算法输出或重新采样，或（2） 迭代到动态状态空间模型。 例如，概率处理器使用物理模型对来自机械系统或医疗仪表或仪器（例如心电图）的数据进行操作。 物理模型的输出产生原始数据的增强的输出，不由医疗计量器输出的第二物理参数的输出或诸如心律失常警告之类的预测。

公开(公告)号：US08303818B2

公开(公告)日：2012-11-06

申请号：US12970512

申请日：2010-12-16

申请人： Roberto Di Salvo ,  Alton Reich ,  H. Waite H. Dykes, Jr. ,  Rodrigo Teixeira

发明人： Roberto Di Salvo ,  Alton Reich ,  H. Waite H. Dykes, Jr. ,  Rodrigo Teixeira

IPC分类号： B01D11/02 ,  C12N1/12 ,  B01D11/04 ,  C02F1/26

CPC分类号： C12N1/06 ,  C12M47/06 ,  C12M47/10 ,  Y02W10/37

摘要： The invention relates to use of an active ionic liquid to dissolve algae cell walls. The ionic liquid is used to, in an energy efficient manner, dissolve and/or lyse an algae cell walls, which releases algae constituents used in the creation of energy, fuel, and/or cosmetic components. The ionic liquids include ionic salts having multiple charge centers, low, very low, and ultra low melting point ionic liquids, and combinations of ionic liquids. An algae treatment system is described, which processes wet algae in a lysing reactor, separates out algae constituent products, and optionally recovers the ionic liquid in an energy efficient manner.

摘要翻译： 本发明涉及使用活性离子液体来溶解藻类细胞壁。 离子液体以能量有效的方式被用于溶解和/或溶解藻类细胞壁，其释放用于产生能量，燃料和/或化妆品组分的藻类成分。 离子液体包括具有多个电荷中心，低，非常低和超低熔点离子液体的离子盐以及离子液体的组合。 描述了一种藻类处理系统，其在裂解反应器中处理湿藻类，分离出藻类成分产物，并且以能量有效的方式任选地回收离子液体。