公开(公告)号：USD672014S1

公开(公告)日：2012-12-04

申请号：US29376320

申请日：2010-10-05

Applicant: Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

Designer： Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

公开(公告)号：US20090091125A1

公开(公告)日：2009-04-09

申请号：US12230401

申请日：2008-08-28

Applicant: Hideyuki Takeda ,  Tetsuya Ishihara ,  Ryo Muramatsu

Inventor： Hideyuki Takeda ,  Tetsuya Ishihara ,  Ryo Muramatsu

IPC: F16L21/08

CPC classification number: F16L23/08 ,  B25B27/10 ,  B25B27/16 ,  F16L23/06 ,  F16L47/14

Abstract: For simply and reliably coupling first and second fluid devices, a fluid device connecting structure is arranged to couple first and second connection parts of the first and second fluid devices by use a coupling member by placing a resin seal member in seal grooves formed in the connection parts. The first connection part includes a first mounting groove for attachment jig and a first fitting groove provided between the first mounting groove and an end face of the first connection part to receive the coupling member. The second connection part includes a second mounting groove for the jig and a second fitting groove provided between the second mounting groove and an end face of the second connection part to receive the coupling member. The coupling member includes a plurality of split members each including a first projecting portion held in contact with an end-face-side inside surface of the first fitting groove and a second projecting portion held in contact with an end-face-side inside surface of the second fitting groove, the first and second projecting portions being arranged at a predetermined distance.

Abstract translation: 为了简单且可靠地联接第一和第二流体装置，流体装置连接结构被布置成通过使用联接构件来将第一和第二流体装置的第一和第二连接部分联接，将树脂密封构件放置在形成在连接中的密封槽中 部分。 第一连接部分包括用于附接夹具的第一安装槽和设置在第一安装槽和第一连接部件的端面之间的第一配合槽，用于接纳联接构件。 第二连接部分包括用于夹具的第二安装槽和设置在第二安装槽和第二连接部的端面之间的第二配合槽，用于接纳联接构件。 联接构件包括多个分割构件，每个分割构件包括与第一装配槽的端面侧内表面保持接触的第一突出部分和与第一装配槽的端面侧内表面接触的第二突出部分 第二装配槽，第一和第二突出部分以预定距离布置。

公开(公告)号：US5767235A

公开(公告)日：1998-06-16

申请号：US367758

申请日：1995-01-03

Applicant: Eriko Nukui ,  Koichi Wada ,  Masaharu Nakano ,  Tadanori Morikawa ,  Kyoichi Kobashi ,  Ryo Muramatsu ,  Akiko Sukesada ,  Satoru Misawa

Inventor： Eriko Nukui ,  Koichi Wada ,  Masaharu Nakano ,  Tadanori Morikawa ,  Kyoichi Kobashi ,  Ryo Muramatsu ,  Akiko Sukesada ,  Satoru Misawa

IPC: A61K38/00 ,  C07K14/815 ,  A61K38/08

CPC classification number: C07K14/815 ,  A61K38/00

Abstract: The present invention relates to hirudin variants having high anti-thrombin and anti-platelet activity, methods for producing them, and anti-coagulants having said variants as active ingredients. Hirudin variants shown in formula (I) having tyrosine residues or having their hydroxyl group sulfated. Methods for producing hirudin variants by sulfating hydroxyl group of said tyrosine residues, and anti-coagulants having hirudin variants shown in formula (I) as active ingredients. Phe-Glu-A-Ile-Pro-B-Tyr(R)-Tyr(R) (I) �In the formula, A represents Glu or Pro, B represents Glu, Tyr (R), Glu-Asp or Glu-Tyr(R), and (R) represents the hydroxy group or its sulfated ester (--O--SO.sub.3 H) of tyrosine residue.!

Abstract translation: 本发明涉及具有高抗凝血酶和抗血小板活性的水蛭素变体，其制备方法和具有所述变体作为活性成分的抗凝血剂。 具有酪氨酸残基或其羟基硫酸化的式（I）所示的水蛭素变体。 通过将所述酪氨酸残基的羟基硫酸化制备水蛭变体的方法和具有式（I）所示水蛭素变体的抗凝血剂作为活性成分。Phe-Glu-A-Ile-Pro-B-Tyr（R）-Tyr R）（I）[式中，A表示Glu或Pro，B表示Glu，Tyr（R），Glu-Asp或Glu-Tyr（R），（R）表示羟基或其硫酸酯（ - O-SO3H）酪氨酸残基。

公开(公告)号：USD671194S1

公开(公告)日：2012-11-20

申请号：US29376298

申请日：2010-10-05

Applicant: Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

Designer： Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

公开(公告)号：US08033579B2

公开(公告)日：2011-10-11

申请号：US12230401

申请日：2008-08-28

Applicant: Hideyuki Takeda ,  Tetsuya Ishihara ,  Ryo Muramatsu

Inventor： Hideyuki Takeda ,  Tetsuya Ishihara ,  Ryo Muramatsu

IPC: F16L23/08 ,  F16L23/16

CPC classification number: F16L23/08 ,  B25B27/10 ,  B25B27/16 ,  F16L23/06 ,  F16L47/14

Abstract: For simply and reliably coupling first and second fluid devices, a fluid device connecting structure is arranged to couple first and second connection parts of the first and second fluid devices by use a coupling member by placing a resin seal member in seal grooves formed in the connection parts. The first connection part includes a first mounting groove for attachment jig and a first fitting groove provided between the first mounting groove and an end face of the first connection part to receive the coupling member. The second connection part includes a second mounting groove for the jig and a second fitting groove provided between the second mounting groove and an end face of the second connection part to receive the coupling member. The coupling member includes a plurality of split members each including a first projecting portion held in contact with an end-face-side inside surface of the first fitting groove and a second projecting portion held in contact with an end-face-side inside surface of the second fitting groove, the first and second projecting portions being arranged at a predetermined distance.

Abstract translation: 为了简单且可靠地联接第一和第二流体装置，流体装置连接结构被布置成通过使用联接构件来将第一和第二流体装置的第一和第二连接部分联接，将树脂密封构件放置在形成在连接中的密封槽中 部分。 第一连接部分包括用于附接夹具的第一安装槽和设置在第一安装槽和第一连接部件的端面之间的第一配合槽，用于接纳联接构件。 第二连接部分包括用于夹具的第二安装槽和设置在第二安装槽和第二连接部的端面之间的第二配合槽，用于接纳联接构件。 联接构件包括多个分割构件，每个分割构件包括与第一装配槽的端面侧内表面保持接触的第一突出部分和与第一装配槽的端面侧内表面接触的第二突出部分 第二装配槽，第一和第二突出部分以预定距离布置。

公开(公告)号：USD672013S1

公开(公告)日：2012-12-04

申请号：US29376296

申请日：2010-10-05

Applicant: Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

Designer： Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

公开(公告)号：USD671621S1

公开(公告)日：2012-11-27

申请号：US29376294

申请日：2010-10-05

Applicant: Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

Designer： Shinji Ikenoya ,  Naofumi Murata ,  Hiroyuki Murase ,  Hideyuki Takeda ,  Ryo Muramatsu

公开(公告)号：US20110194201A1

公开(公告)日：2011-08-11

申请号：US12957753

申请日：2010-12-01

Applicant: Ryo MURAMATSU

Inventor： Ryo MURAMATSU

IPC: B60R1/06

CPC classification number: B60R1/06 ,  B60J5/0404

Abstract: If a lip portion of a gasket is brought into contact with a peripheral wall face on the upper side of a door mirror mounting portion strongly from an arrow A direction, an elastic portion is largely deformed so as to deflect outward when the lip portion is retreated, and the lip portion controls a force that hits the peripheral wall face of the door mirror mounting portion. Therefore, whether a distal end portion of the lip portion hits the peripheral wall face of the door mirror mounting portion disposed on a front door weakly or strongly due to variation in accuracy of a component, the distal end portion of the lip portion and the peripheral wall face of the door mirror mounting portion can be reliably brought into close contact with each other. And a gap is hardly generated between the peripheral wall face on the upper side of the door mirror mounting portion and the lip portion, generation of a wind noise can be prevented, water tightness can be improved, and contribution is made to improvement of an appearance quality of a joint when a door mirror is attached to the front door.

Abstract translation: 如果垫圈的唇部与箭头A方向上的车门反射镜安装部的上侧的周壁面接触，则当唇部退避时，弹性部分发生大的变形，从而向外偏转 并且唇部控制撞击车门后视镜安装部的周壁面的力。 因此，由于部件的精度的变化，唇部的前端部分是否轻微或强烈地撞击设置在前门上的车门后视镜安装部的周壁面，唇部的前端部分和周边 门镜安装部的壁面能够可靠地彼此紧密接触。 并且，在门镜安装部的上侧的周壁面与唇部之间几乎不产生间隙，能够防止风噪声的产生，可以提高防水性，并且有助于提高外观 当门镜连接到前门时，接头的质量。

公开(公告)号：US5880258A

公开(公告)日：1999-03-09

申请号：US909735

申请日：1997-08-12

Applicant: Ryo Muramatsu ,  Akiko Sukesada ,  Satoru Misawa ,  Eriko Nukui ,  Koichi Wada ,  Masaharu Nakano ,  Tadanori Morikawa ,  Kyoichi Kobashi

Inventor： Ryo Muramatsu ,  Akiko Sukesada ,  Satoru Misawa ,  Eriko Nukui ,  Koichi Wada ,  Masaharu Nakano ,  Tadanori Morikawa ,  Kyoichi Kobashi

IPC: A61K38/00 ,  C07K14/815 ,  C07K14/00

CPC classification number: C07K14/815 ,  A61K38/00

Abstract: The present invention relates to hirudin variants having high anti-thrombin and anti-platelet activity, methods for producing them, and anti-coagulants having said variants as active ingredients.Hirudin variants shown in formula (I) having tyrosine residues or having their hydroxyl group sulfated.Methods for producing hirudin variants by sulfating hydroxyl group of said tyrosine residues, and anti-coagulants having hirudin variants shown in formula (I) as active ingredients.Phe-Glu-A-Ile-Pro-D-Tyr(R) Tyr(R) (I)�In the formula, A represents Glu or Pro, R represents Glu, Tyr (R), Glu-Asp or Glu-Tyr(R), and (R) represents the hydroxy group or its sulfated ester (--O--SO.sub.3 H) of tyrosine residue.!

Abstract translation: 本发明涉及具有高抗凝血酶和抗血小板活性的水蛭素变体，其制备方法和具有所述变体作为活性成分的抗凝血剂。 具有酪氨酸残基或其羟基硫酸化的式（I）所示的水蛭素变体。 通过硫酸化所述酪氨酸残基的羟基来生产水蛭变异体的方法和具有式（I）所示的水蛭素变体的抗凝血剂作为活性成分。Phe-Glu-A-Ile-Pro-D-Tyr（R）Tyr ）（I）[式中，A表示Glu或Pro，R表示Glu，Tyr（R），Glu-Asp或Glu-Tyr（R），（R）表示羟基或其硫酸酯 -SO3H）酪氨酸残基。

公开(公告)号：US5226987A

公开(公告)日：1993-07-13

申请号：US715051

申请日：1991-06-12

Applicant: Yo Matsumoto ,  Tetsuto Ueno ,  Ryo Muramatsu

Inventor： Yo Matsumoto ,  Tetsuto Ueno ,  Ryo Muramatsu

IPC: B60C9/18 ,  B60C11/00

CPC classification number: B60C9/18 ,  B60C11/00 ,  B60C11/005 ,  Y10T152/1081

Abstract: A radial tire for heavy load vehicles having a steel cord-reinforced belt interposed between the carcass of radial structure and the tread, which comprises a rubber reinforcing layer extending from the center toward the edges along the inside of the tread and having at least one quarter the tread width, said rubber reinforcing layer being made of a rubber composition containing resorcin or a resorcin derivative as a reinforcing agent in addition to carbon black and silica and also containing hexamethylenetetramine or a melamine derivative as a methylene donor, said rubber reinforcing layer having a reinforcing factor of 2.2 to 5.7 which is defined by .sqroot.E'.multidot.d [where E' denotes the dynamic modulus (MPa) of the rubber reinforcing layer and d denotes the thickness (mm) of the rubber reinforcing layer].

Abstract translation: 一种用于重载车辆的子午线轮胎，其具有插入在径向结构的胎体之间的钢丝绳加强带和胎面，其包括沿着胎面的内部从中心向边缘延伸的橡胶加强层，并且具有至少四分之一 所述橡胶增强层除了炭黑和二氧化硅之外还包含含有间苯二酚或间苯二酚衍生物作为增强剂的橡胶组合物，并且还含有六亚甲基四胺或作为亚甲基供体的三聚氰胺衍生物，所述橡胶增强层具有 由2ROOT E'xd [其中E'表示橡胶增强层的动态模量（MPa），d表示橡胶增强层的厚度（mm）]定义的2.2至5.7的增强因子。