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公开(公告)号：US20240180083A1
公开(公告)日：2024-06-06
申请号：US18486332
申请日：2023-10-13
申请人： Sara Blumenstein , Phil Cook
发明人： Sara Blumenstein , Phil Cook
IPC分类号： A01G5/04
CPC分类号： A01G5/04
摘要： A mounting system for securing a decorative structure to an object includes an assembly configured to be secured to the object and a holder coupled to the assembly. The holder defines a first slot through a first end face of the holder. The first slot is configured to receive a portion of the decorative structure to secure the decorative structure to the holder and the assembly when the assembly is coupled to the object. The first slot may have a Y-shaped configuration.
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2.发明授权FGF-2 variants having N-terminal deletions and increased receptor selectivity and uses thereof 有权具有N末端缺失和增加的受体选择性的FGF-2变体及其用途公开(公告)号：US08962556B2
公开(公告)日：2015-02-24
申请号：US12443638
申请日：2007-10-07
申请人： Avner Yayon , Eran Rom , Irina Chumakov , Sara Blumenstein
发明人： Avner Yayon , Eran Rom , Irina Chumakov , Sara Blumenstein
CPC分类号： C07K14/503 , A61K38/00 , A61K38/1825 , C07K14/50
摘要： The present invention relates to the design, manufacture and use of fibroblast growth factor (FGF) polypeptides having improved receptor specificity. In particular, the invention relates to isolated FGF2 and FGF4 polypeptides that include a truncated N-terminus and optionally N-terminal amino acid substitutions. The present invention provides polypeptides, nucleic acids encoding the polypeptides, compositions of the same and methods for use thereof.
摘要翻译： 本发明涉及具有改善的受体特异性的成纤维细胞生长因子（FGF）多肽的设计，制造和应用。 特别地，本发明涉及分离的FGF2和FGF4多肽，其包括截短的N-末端和任选的N-末端氨基酸取代。 本发明提供多肽，编码多肽的核酸，其组合物及其使用方法。
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3.发明申请METHODS AND KITS FOR DETERMINING A RISK TO DEVELOP CANCER, FOR EVALUATING AN EFFECTIVENESS AND DOSAGE OF CANCER THERAPY AND FOR CORRELATING BETWEEN AN ACTIVITY OF A DNA REPAIR ENZYME AND A CANCER 审中-公开用于确定癌症风险的方法和工具，用于评估癌症治疗的有效性和剂量以及与DNA修复酶和癌症活性之间的相关性公开(公告)号：US20110294134A1
公开(公告)日：2011-12-01
申请号：US13204737
申请日：2011-08-08
申请人： ZVI LIVNEH , TAMAR PAZ-ELIZUR , SARA BLUMENSTEIN
发明人： ZVI LIVNEH , TAMAR PAZ-ELIZUR , SARA BLUMENSTEIN
CPC分类号： G01N33/574 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N2333/924 , G01N2333/988 , G01N2800/52
摘要： Methods and kits for (i) determining a risk of a subject to develop cancer; (ii) evaluating an effectiveness and dosage of cancer therapy administered to a cancer patient; and (iii) determining a presence of correlation or non-correlation between an activity of at least one DNA repair enzyme and at least one cancer, are disclosed.
摘要翻译： 方法和试剂盒，用于（i）确定受试者发展癌症的风险; （ii）评估给予癌症患者的癌症治疗的有效性和剂量; 并且（iii）确定至少一种DNA修复酶与至少一种癌症的活性之间的相关性或非相关性的存在。
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4.发明授权Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer 有权用于确定发展癌症的风险的方法和试剂盒，用于评估癌症治疗的有效性和剂量以及DNA修复酶与癌症的活性之间的相关性公开(公告)号：US08043807B2
公开(公告)日：2011-10-25
申请号：US10469992
申请日：2002-03-21
申请人： Zvi Livneh , Tamar Paz-Elizur , Sara Blumenstein
发明人： Zvi Livneh , Tamar Paz-Elizur , Sara Blumenstein
CPC分类号： G01N33/574 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158 , G01N2333/924 , G01N2333/988 , G01N2800/52
摘要： Methods and kits for (i) determining a risk of a subject to develop cancer; (ii) evaluating an effectiveness and dosage of cancer therapy administered to a cancer patient; and (iii) determining a presence of correlation or non-correlation between an activity of at least one DNA repair enzyme and at least one cancer, are disclosed.
摘要翻译： 方法和试剂盒，用于（i）确定受试者发展癌症的风险; （ii）评估给予癌症患者的癌症治疗的有效性和剂量; 并且（iii）确定至少一种DNA修复酶与至少一种癌症的活性之间的相关性或非相关性的存在。
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5.发明申请N-TERMINAL FGF VARIANTS HAVING INCREASED RECEPTOR SELECTIVITY AND USES THEREOF 有权具有增加的受体选择性的N-末端FGF变体及其用途公开(公告)号：US20110053841A1
公开(公告)日：2011-03-03
申请号：US12443638
申请日：2007-10-07
申请人： Avner Yayon , Eran Rom , Irina Chumakov , Sara Blumenstein
发明人： Avner Yayon , Eran Rom , Irina Chumakov , Sara Blumenstein
IPC分类号： A61K38/18 , C07K14/50 , C07H21/00 , C12N15/63 , C12N1/21 , A61K31/7088 , C12N5/071 , C12N5/078 , C12N5/077 , A61P17/02 , A61P19/08 , A61P9/00
CPC分类号： C07K14/503 , A61K38/00 , A61K38/1825 , C07K14/50
摘要： The present invention relates to the design, manufacture and use of fibroblast growth factor (FGF) polypeptides having improved receptor specificity. In particular, the invention relates to isolated FGF2 and FGF4 polypeptides that include a truncated N-terminus and optionally N-terminal amino acid substitutions. The present invention provides polypeptides, nucleic acids encoding the polypeptides, compositions of the same and methods for use thereof.
摘要翻译： 本发明涉及具有改善的受体特异性的成纤维细胞生长因子（FGF）多肽的设计，制造和应用。 特别地，本发明涉及分离的FGF2和FGF4多肽，其包括截短的N-末端和任选的N-末端氨基酸取代。 本发明提供多肽，编码多肽的核酸，其组合物及其使用方法。
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