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    Optimizing a file system interface in a virtualized computing environment
    1.
    发明授权
    Optimizing a file system interface in a virtualized computing environment 有权
    在虚拟化计算环境中优化文件系统界面

    公开(公告)号：US09229757B2

    公开(公告)日：2016-01-05

    申请号：US12838508

    申请日：2010-07-19

    Applicant: Shmuel Ben-Yehuda ,  Eran Borovik ,  Eran Rom ,  Avishay Traeger

    Inventor： Shmuel Ben-Yehuda ,  Eran Borovik ,  Eran Rom ,  Avishay Traeger

    IPC: G06F9/455 ,  G06F12/08

    CPC classification number: G06F9/4555 ,  G06F9/45558 ,  G06F9/5016 ,  G06F12/0802 ,  G06F12/0875 ,  G06F2009/45579 ,  G06F2212/452

    Abstract: Systems and methods for optimizing write operations to a storage device in a virtualized computing environment comprise monitoring write operations issued by an application running on a virtual machine's (VM) operating system, wherein the VM is hosted by a hypervisor providing access to a storage device in a virtualized computing environment; and causing a virtual file system (VFS) supported by the operating system to call on a first para-virtualized file system (PVFS FE) supported by the operating system to execute a write operation, in response to determining that the write operation is to write data to the storage device, wherein data that is to be written to the storage device is first written to a VM memory area allocated to the VM and accessible to the hypervisor hosting the VM.

    Abstract translation: 用于优化对虚拟化计算环境中的存储设备的写入操作的系统和方法包括监视由在虚拟机（VM）操作系统上运行的应用程序发出的写入操作，其中VM由管理程序托管，该管理程序提供对存储设备的访问 虚拟化计算环境; 以及使所述操作系统支持的虚拟文件系统（VFS）在所述操作系统支持的第一副虚拟化文件系统（PVFS FE）上执行写入操作，响应于确定所述写入操作要写入 数据到存储设备，其中要写入存储设备的数据首先被写入分配给虚拟机的VM存储器区域，并且可以由托管虚拟机的管理程序访问。

    Efficient file system object-based deduplication
    2.
    发明授权
    Efficient file system object-based deduplication 失效
    高效的文件系统对象重复数据删除

    公开(公告)号：US08706703B2

    公开(公告)日：2014-04-22

    申请号：US13169069

    申请日：2011-06-27

    Applicant: Michael Factor ,  Joseph Samuel Glider ,  Danny Harnik ,  Elliot K. Kolodner ,  Dalit Naor ,  Demyn Lee Plantenberg ,  Eran Rom ,  Sivan Tal ,  Paula Ta-Shma

    Inventor： Michael Factor ,  Joseph Samuel Glider ,  Danny Harnik ,  Elliot K. Kolodner ,  Dalit Naor ,  Demyn Lee Plantenberg ,  Eran Rom ,  Sivan Tal ,  Paula Ta-Shma

    IPC: G06F7/20

    CPC classification number: G06F17/30156

    Abstract: In accordance with one or more embodiments, an inode implemented file system may be utilized to support both offline and inline deduplication. When the first content is stored in the storage medium, one inode is used to associate a filename with the data blocks where the first content is stored. When a second content that is a duplicate of the first content is to be stored, then a parent inode is created to point to the data blocks in which a copy of the first content is stored. Further, two inodes are created, one representing the first content and the other representing the second content. Both inodes point to the same parent inode that points to the data blocks where the first content is stored.

    Abstract translation: 根据一个或多个实施例，可以使用inode实现的文件系统来支持脱机和内联重复数据删除。 当第一内容存储在存储介质中时，使用一个inode来将文件名与存储第一内容的数据块相关联。 当要存储与第一内容重复的第二内容时，创建父节点，以指向存储第一内容的副本的数据块。 此外，创建两个inode，一个代表第一内容，另一个代表第二内容。 两个inode指向同一个父节点，它指向存储第一个内容的数据块。

    EFFICIENT FILE SYSTEM OBJECT-BASED DEDUPLICATION
    3.
    发明申请
    EFFICIENT FILE SYSTEM OBJECT-BASED DEDUPLICATION 失效
    高效的文件系统基于对象的重用

    公开(公告)号：US20120330904A1

    公开(公告)日：2012-12-27

    申请号：US13169069

    申请日：2011-06-27

    Applicant: Michael Factor ,  Joseph Samuel Glider ,  Danny Harnik ,  Elliot K. Kolodner ,  Dalit Naor ,  Demyn Lee Plantenberg ,  Eran Rom ,  Sivan Tal ,  Paula Ta-Shma

    Inventor： Michael Factor ,  Joseph Samuel Glider ,  Danny Harnik ,  Elliot K. Kolodner ,  Dalit Naor ,  Demyn Lee Plantenberg ,  Eran Rom ,  Sivan Tal ,  Paula Ta-Shma

    IPC: G06F17/30

    CPC classification number: G06F17/30156

    Abstract: In accordance with one or more embodiments, an inode implemented file system may be utilized to support both offline and inline deduplication. When the first content is stored in the storage medium, one inode is used to associate a filename with the data blocks where the first content is stored. When a second content that is a duplicate of the first content is to be stored, then a parent inode is created to point to the data blocks in which a copy of the first content is stored. Further, two inodes are created, one representing the first content and the other representing the second content. Both inodes point to the same parent inode that points to the data blocks where the first content is stored.

    Abstract translation: 根据一个或多个实施例，可以使用inode实现的文件系统来支持脱机和内联重复数据删除。 当第一内容存储在存储介质中时，使用一个inode来将文件名与存储第一内容的数据块相关联。 当要存储与第一内容重复的第二内容时，创建父节点，以指向存储第一内容的副本的数据块。 此外，创建两个inode，一个代表第一内容，另一个代表第二内容。 两个inode指向同一个父节点，它指向存储第一个内容的数据块。

    ANTIBODIES BLOCKING FIBROBLAST GROWTH FACTOR RECEPTOR ACTIVATION AND METHODS OF USE THEREOF
    5.
    发明申请
    ANTIBODIES BLOCKING FIBROBLAST GROWTH FACTOR RECEPTOR ACTIVATION AND METHODS OF USE THEREOF 有权
    抗体阻断纤维生长因子受体激活及其使用方法

    公开(公告)号：US20100047251A1

    公开(公告)日：2010-02-25

    申请号：US12304638

    申请日：2007-06-17

    Applicant: Avner Yayon ,  Eran Rom

    Inventor： Avner Yayon ,  Eran Rom

    IPC: A61K39/395 ,  C07K16/18 ,  C07K16/22 ,  A61P35/00

    CPC classification number: C07K16/2863 ,  C07K2317/21 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/76

    Abstract: The present invention is related to antibodies with binding affinity to fibroblast growth factor receptor 2 (FGFR2) optionally with binding affinity to other FGF receptors, which block both ligand-dependent and constitutive ligand independent receptor activation. Specifically, the present invention relates to antibodies with high affinity to more than one FGF receptor subtype, and fragments thereof, useful in treating disorders including cell proliferative diseases.

    Abstract translation: 本发明涉及对成纤维细胞生长因子受体2（FGFR2）具有结合亲和力的任何与其它FGF受体结合亲和力的抗体，其阻断配体依赖性和组成型配体独立受体活化。 具体地，本发明涉及对多于一种FGF受体亚型具有高亲和力的抗体及其片段，其可用于治疗包括细胞增殖性疾病的病症。

    TREATMENT OF B-CELL MALIGNANCIES
    7.
    发明申请
    TREATMENT OF B-CELL MALIGNANCIES 审中-公开
    B细胞恶性肿瘤的治疗

    公开(公告)号：US20090175866A1

    公开(公告)日：2009-07-09

    申请号：US11718530

    申请日：2005-11-03

    Applicant: Avner Yayon ,  Eran Rom ,  Suzanne Trudel

    Inventor： Avner Yayon ,  Eran Rom ,  Suzanne Trudel

    IPC: A61K39/395

    CPC classification number: C07K16/2863 ,  A61K2039/505 ,  C07K2317/55 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/76

    Abstract: The present invention generally relates to a pharmaceutical composition and to an improved method of preventing, attenuating and treating multiple myeloma by administering to an individual in need thereof at least one antibody to fibroblast growth factor receptor 3 (FGFR3). In particular, the at least one FGR3 antibody induces apoptosis of myeloma cells expressing wild type FGFR3.

    Abstract translation: 本发明一般涉及一种药物组合物和通过向有需要的个体施用至少一种成纤维细胞生长因子受体3（FGFR3）抗体来预防，减弱和治疗多发性骨髓瘤的改进方法。 特别地，至少一种FGR3抗体诱导表达野生型FGFR3的骨髓瘤细胞的凋亡。

    OPTIMIZING A FILE SYSTEM INTERFACE IN A VIRTUALIZED COMPUTING ENVIRONMENT
    10.
    发明申请
    OPTIMIZING A FILE SYSTEM INTERFACE IN A VIRTUALIZED COMPUTING ENVIRONMENT 有权
    优化虚拟化计算环境中的文件系统界面

    公开(公告)号：US20120017209A1

    公开(公告)日：2012-01-19

    申请号：US12838518

    申请日：2010-07-19

    Applicant: Shmuel Ben-Yehuda ,  Eran Borovik ,  Eran Rom ,  Avishay Traeger

    Inventor： Shmuel Ben-Yehuda ,  Eran Borovik ,  Eran Rom ,  Avishay Traeger

    IPC: G06F9/455

    CPC classification number: G06F9/45558 ,  G06F2009/45579

    Abstract: Systems and methods for optimizing read operations from a storage device in a virtualized computing environment are provided. One method comprises monitoring read operations issued by an application running on a virtual machine's (VM) operating system, wherein the VM is hosted by a hypervisor providing access to a storage device in a virtualized computing environment; and causing a virtual file system (VFS) supported by the operating system to call on a first para-virtualized file system (PVFS FE) supported by the operating system to execute a read operation, in response to determining that the read operation is for reading target data from the storage device.

    Abstract translation: 提供了用于在虚拟化计算环境中优化来自存储设备的读取操作的系统和方法。 一种方法包括监视由在虚拟机（VM）操作系统上运行的应用程序发出的读取操作，其中VM由虚拟机管理程序托管，虚拟机管理程序提供对虚拟化计算环境中的存储设备的访问; 以及使所述操作系统支持的虚拟文件系统（VFS）在所述操作系统支持的第一副虚拟化文件系统（PVFS FE）上呼叫以执行读取操作，以响应于所述读取操作用于读取 来自存储设备的目标数据。

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