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1.发明授权Hand held micro PCR device including microcontroller for exchanging information with a communications interface 有权手持式微PCR装置，包括用于与通信接口交换信息的微控制器公开(公告)号：US09370774B2
公开(公告)日：2016-06-21
申请号：US12682555
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah , Sudip Mondal , Venkatakrishnan Venkataraman
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah , Sudip Mondal , Venkatakrishnan Venkataraman
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a hand held micro PCR device comprising a LTCC micro PCR chip comprising a heater, a reaction chamber to load a sample. It also comprises a heater control to regulate the heater on basis of input received from a temperature sensor. It further has an optical system having an optical fiber to detect a fluorescence signal from the sample, and at least one communication interface to interact with other device(s).
摘要翻译： 本发明涉及一种手持式微PCR装置，其包含LTCC微PCR芯片，其包括加热器，负载样品的反应室。 它还包括加热器控制，以根据从温度传感器接收的输入来调节加热器。 它还具有光学系统，其具有用于检测来自样品的荧光信号的光纤，以及至少一个通信接口以与其他设备相互作用。
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公开(公告)号：US20100240044A1
公开(公告)日：2010-09-23
申请号：US12682581
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a micro chip comprising plurality of layers of LTCC wherein a reaction chamber is formed in plurality of top layers to load samples. A heater embedded in at least one of the layers below the reaction chamber and a temperature sensor is embedded in at least one of the layers between the heater and the reaction chamber for analyzing the sample. The temperature sensor can be placed outside the chip to measure the chip temperature.
摘要翻译： 即时发明是关于包括多层LTCC的微芯片，其中反应室形成在多个顶层中以加载样品。 嵌入在反应室下面的至少一个层的加热器和温度传感器被嵌入在加热器和反应室之间的至少一个层中，用于分析样品。 温度传感器可以放置在芯片外部以测量芯片温度。
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公开(公告)号：US09044754B2
公开(公告)日：2015-06-02
申请号：US12682581
申请日：2008-10-13
申请人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
发明人： Kishore Krishna Kumar , Raviprakash Jayaraman , Sankaranand Kaipa Narasimha , Renjith Mahiladevi Radhakrishnan , Sathyadeep Viswanathan , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao , Manjula Jagannath , Shilpa Chennakrishnaiah
CPC分类号： B01L7/52 , B01L3/5027 , B01L2300/0627 , B01L2300/0851 , B01L2300/0887 , B01L2300/16 , B01L2300/1805
摘要： Instant invention is about a micro chip comprising plurality of layers of LTCC wherein a reaction chamber is formed in plurality of top layers to load samples. A heater embedded in at least one of the layers below the reaction chamber and a temperature sensor is embedded in at least one of the layers between the heater and the reaction chamber for analyzing the sample. The temperature sensor can be placed outside the chip to measure the chip temperature.
摘要翻译： 即时发明是关于包括多层LTCC的微芯片，其中反应室形成在多个顶层中以加载样品。 嵌入在反应室下面的至少一个层的加热器和温度传感器被嵌入在加热器和反应室之间的至少一个层中，用于分析样品。 温度传感器可以放置在芯片外部以测量芯片温度。
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4.发明授权Non contact real time micro polymerase chain reaction system and method thereof 有权非接触式实时微聚合酶链反应体系及其方法公开(公告)号：US09404151B2
公开(公告)日：2016-08-02
申请号：US13695254
申请日：2011-04-28
申请人： Swetha Chandra , Sudip Mondal , Venkataraman Venkatakrishnan , Sathyadeep Viswanathan , Renjith Mahiladevi Radhakrishnan , Raviprakash Jayaraman , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao
发明人： Swetha Chandra , Sudip Mondal , Venkataraman Venkatakrishnan , Sathyadeep Viswanathan , Renjith Mahiladevi Radhakrishnan , Raviprakash Jayaraman , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao
CPC分类号： C12Q1/686 , B01L7/52 , B01L2200/027 , B01L2200/0684 , B01L2200/147 , B01L2300/0816 , B01L2300/0887 , B01L2300/12 , B01L2300/1816 , C12Q3/00
摘要： The present disclosure provides a non-contact real time micro Polymerase Chain Reaction (PCR) system comprising; a chip having a reaction chamber for holding a sample and an embedded metal heater below the reaction chamber for heating the sample; an optical unit comprising an associated LED driver and a photo detector amplifier placed above the chip to detect fluorescence; an induction heater mounted around the chip and inductively coupled to the metal heater; an infrared temperature sensor mounted below the chip for measuring a temperature of the metal heater, wherein the infrared temperature sensor is interfaced with a signal conditioner; and a controller interfaced with the signal conditioner and the induction heater for regulating the power to the induction heater based on feedback received from the infrared temperature sensor through the signal conditioner.
摘要翻译： 本公开提供了非接触式实时微聚合酶链式反应（PCR）系统，其包含： 具有用于保持样品的反应室和用于加热样品的反应室下面的嵌入式金属加热器的芯片; 光学单元，包括相关联的LED驱动器和放置在芯片上方以检测荧光的光电检测放大器; 安装在芯片周围并感应耦合到金属加热器的感应加热器; 安装在所述芯片下方的用于测量所述金属加热器的温度的红外温度传感器，其中所述红外温度传感器与信号调节器接口; 以及与信号调节器和感应加热器接口的控制器，其基于通过信号调节器从红外温度传感器接收的反馈来调节对感应加热器的电力。
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5.发明申请NON CONTACT REAL TIME MICRO POLYMERASE CHAIN REACTION SYSTEM AND METHOD THEREOF 有权非接触实时微聚合物链反应体系及其方法公开(公告)号：US20130101983A1
公开(公告)日：2013-04-25
申请号：US13695254
申请日：2011-04-28
申请人： Swetha Chandra , Sudip Mondal , Venkataraman Venkatakrishnan , Sathyadeep Viswanathan , Renjith Mahiladevi Radhakrishnan , Raviprakash Jayaraman , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao
发明人： Swetha Chandra , Sudip Mondal , Venkataraman Venkatakrishnan , Sathyadeep Viswanathan , Renjith Mahiladevi Radhakrishnan , Raviprakash Jayaraman , Chandrasekhar Bhaskaran Nair , Pillarisetti Venkata Subbarao
CPC分类号： C12Q1/686 , B01L7/52 , B01L2200/027 , B01L2200/0684 , B01L2200/147 , B01L2300/0816 , B01L2300/0887 , B01L2300/12 , B01L2300/1816 , C12Q3/00
摘要： The present disclosure provides a non contact real time micro Polymerase Chain Reaction [PCR] system comprises; a chip having a reaction chamber for holding a sample and an embedded metal heater below the reaction chamber for heating the sample; an optical unit comprising associated LED driver and photo detector amplifier placed above the chip to detect the fluorescence; an induction heater mounted around the chip and is inductively coupled to the metal heater; an infrared temperature sensor mounted below the chip for measuring a temperature of the metal heater, wherein said infrared temperature sensor is interfaced with a signal conditioner; and a controller interfaced with the signal conditioner and the induction heater for regulating the power to the induction heater based on feedback received from the infrared temperature sensor through the signal conditioner.
摘要翻译： 本公开提供了非接触式实时微聚合酶链式反应[PCR]系统，包括： 具有用于保持样品的反应室和用于加热样品的反应室下面的嵌入式金属加热器的芯片; 光学单元，包括放置在芯片上方的相关联的LED驱动器和光电检测放大器，以检测荧光; 感应加热器，安装在芯片周围，并感应耦合到金属加热器; 安装在所述芯片下方的用于测量所述金属加热器的温度的红外温度传感器，其中所述红外温度传感器与信号调节器接口; 以及控制器，其与信号调节器和感应加热器接口，用于基于通过信号调节器从红外温度传感器接收的反馈来调节对感应加热器的电力。
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