公开(公告)号：US07317014B2

公开(公告)日：2008-01-08

申请号：US10469647

申请日：2003-07-21

Applicant: Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

Inventor： Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

IPC: C07D239/30 ,  C07D239/48 ,  A61K31/505

CPC classification number: C07D239/30 ,  C07D239/36 ,  C07D239/38 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/56

Abstract: The present invention relates to novel derivatives of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention more particularly provides novel pyrimidine derivatives of the general formula (I)

Abstract translation: 本发明涉及通式（I）的新衍生物，其衍生物，其类似物，其互变异构形式，它们的立体异构体，其多晶型物，它们的水合物，它们的溶剂化物，其药学上可接受的盐和含有它们的药学上可接受的组合物。 本发明更具体地提供了通式（I）的新型嘧啶衍生物，

公开(公告)号：US07101873B2

公开(公告)日：2006-09-05

申请号：US10409153

申请日：2003-04-09

Applicant: Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

Inventor： Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

IPC: A61K31/54

CPC classification number: C07D239/54

Abstract: Pyrimidinedione derivatives of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them are useful for the treatment of inflammation and immunological diseases

Abstract translation: 通式（I）的嘧啶二酮衍生物，其衍生物，类似物，互变异构体形式，立体异构体，多晶型物，水合物，溶剂合物，药学上可接受的盐和含有它们的药学上可接受的组合物可用于治疗炎症和免疫疾病

公开(公告)号：US07399760B2

公开(公告)日：2008-07-15

申请号：US11414229

申请日：2006-05-01

Applicant: Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

Inventor： Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

IPC: A61K31/54

CPC classification number: C07D239/54

Abstract: Pyrimidinedione derivatives of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them are useful for the treatment of inflammation and immunological diseases.

Abstract translation: 通式（I）的嘧啶二酮衍生物，其衍生物，类似物，互变异构形式，立体异构体，多晶型物，水合物，溶剂化物，药学上可接受的盐和含有它们的药学上可接受的组合物可用于治疗炎症和免疫疾病。

公开(公告)号：US07365069B2

公开(公告)日：2008-04-29

申请号：US10827368

申请日：2004-04-20

Applicant: Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar ,  Debendranath Dey ,  Biswajit Nag

Inventor： Shiv Kumar Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar ,  Debendranath Dey ,  Biswajit Nag

IPC: C07D239/36 ,  A61K31/513

CPC classification number: C07D239/36 ,  C07C69/738 ,  C07C257/18 ,  C07C317/44 ,  C07C317/48 ,  C07C317/50 ,  C07C323/42 ,  C07C323/44 ,  C07C323/62 ,  C07C327/48 ,  C07C327/58 ,  C07D239/48 ,  C07D239/54 ,  C07D239/56 ,  C07D265/06

Abstract: The present invention relates to novel pyrimidones of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention more particularly novel pyrimidones of the general formula (I)

Abstract translation: 本发明涉及通式（I）的新型嘧啶，它们的衍生物，它们的类似物，它们的互变异构形式，它们的立体异构体，它们的多晶形物，它们的水合物，它们的溶剂化物，它们的药学上可接受的盐和含有它们的药学上可接受的组合物。 本发明更具体地是通式（I）的新颖的嘧啶酮，

公开(公告)号：US20060194799A1

公开(公告)日：2006-08-31

申请号：US11414229

申请日：2006-05-01

Applicant: Shiv Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

Inventor： Shiv Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

IPC: C07D413/12 ,  A61K31/54 ,  A61K31/655

CPC classification number: C07D239/54

Abstract: Pyrimidinedione derivatives of the general formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, hydrates, solvates, pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them are useful for the treatment of inflammation and immunological diseases.

Abstract translation: 通式（I）的嘧啶二酮衍生物，其衍生物，类似物，互变异构形式，立体异构体，多晶型物，水合物，溶剂化物，药学上可接受的盐和含有它们的药学上可接受的组合物可用于治疗炎症和免疫疾病。

公开(公告)号：US20050107413A1

公开(公告)日：2005-05-19

申请号：US10469647

申请日：2003-07-21

Applicant: Shiv Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

Inventor： Shiv Agarwal ,  Ravikumar Tadiparthi ,  Pawan Aggarwal ,  Savithiri Shivakumar

IPC: C07D239/30 ,  A61K31/505 ,  A61K31/513 ,  A61P1/04 ,  A61P1/18 ,  A61P3/10 ,  A61P7/00 ,  A61P9/00 ,  A61P9/10 ,  A61P11/00 ,  A61P11/02 ,  A61P11/06 ,  A61P17/00 ,  A61P17/06 ,  A61P19/00 ,  A61P19/02 ,  A61P19/06 ,  A61P19/10 ,  A61P21/00 ,  A61P25/00 ,  A61P29/00 ,  A61P29/02 ,  A61P31/00 ,  A61P31/16 ,  A61P31/18 ,  A61P31/22 ,  A61P35/00 ,  A61P35/02 ,  A61P37/02 ,  A61P37/08 ,  A61P43/00 ,  C07D239/34 ,  C07D239/36 ,  C07D239/38 ,  C07D239/42 ,  C07D239/46 ,  C07D239/48 ,  C07D239/56

CPC classification number: C07D239/30 ,  C07D239/36 ,  C07D239/38 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/56

Abstract: The present invention relates to novel derivatives of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them. The present invention more particularly provides novel pyrimidine derivatives of the general formula (I).

Abstract translation: 本发明涉及通式（I）的新衍生物，其衍生物，其类似物，其互变异构形式，它们的立体异构体，其多晶型物，它们的水合物，它们的溶剂化物，其药学上可接受的盐和含有它们的药学上可接受的组合物。 本发明更具体地提供了通式（I）的新型嘧啶衍生物。