公开(公告)号：US08562826B2

公开(公告)日：2013-10-22

申请号：US12704336

申请日：2010-02-11

Applicant: Daniel M. Bailey ,  Philippe Vernot ,  Sebastien Lefebvre

Inventor： Daniel M. Bailey ,  Philippe Vernot ,  Sebastien Lefebvre

IPC: B01D15/08

CPC classification number: B01D15/22 ,  G01N30/6047

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract translation: 在制备色谱柱中用作上壳体的柱塞由一个或多个杆悬挂，所述杆由框架支撑，框架上的联接连接件可以相对于框架固定杆的位置，而位置 的杆由一个悬挂在柱上方的电动驱动系统控制。 驱动系统安装在柱盖或定位在柱盖上方短距离的功能板上。 这些结构允许柱塞被升高和降低，使得柱和其部件可以更换，而不需要起重机或起重机。

公开(公告)号：US20100193441A1

公开(公告)日：2010-08-05

申请号：US12755249

申请日：2010-04-06

Applicant: Maurice Agee ,  Sebastien Lefebvre ,  Sebastien Magnaud ,  Philippe Vernot

Inventor： Maurice Agee ,  Sebastien Lefebvre ,  Sebastien Magnaud ,  Philippe Vernot

IPC: B01D15/22

CPC classification number: G01N30/6004 ,  B01D15/20 ,  B01D15/206 ,  B01D15/22 ,  G01N30/56

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.

Abstract translation: 制备色谱柱配备有一个或多个阀，每个阀都可以用于将塔填料注入塔中或从塔中抽出用过的填料，除了清洁与阀本身相关的供给和排出管线之外，全部由 将可动塞移动到阀体内，而不会突出到柱内部。 每个阀门安装在立柱底部的过滤板正上方的柱的侧壁上，并且塞子可以在闭合位置之间移动，其中塞子的端面与柱的内壁齐平，并且打开 插头凹入孔内的位置。 每个阀在其阀体中具有两个附加端口，定位成使得当塞子闭合时，两个端口都对阀孔开放，并且当塞子打开时，至少一个端口对孔开放。 插头在阀孔内的位置决定了阀门的功能。

公开(公告)号：USD467502S1

公开(公告)日：2002-12-24

申请号：US29109468

申请日：1999-08-16

Applicant: Gilles Keller ,  Sebastien Lefebvre ,  Frank Haesendonckx ,  Laurent Degroote ,  Cor Jansen

Designer： Gilles Keller ,  Sebastien Lefebvre ,  Frank Haesendonckx ,  Laurent Degroote ,  Cor Jansen

公开(公告)号：US20100140174A1

公开(公告)日：2010-06-10

申请号：US12709698

申请日：2010-02-22

Applicant: Daniel M. Bailey ,  Philippe Vernot ,  Sebastien Lefebvre

Inventor： Daniel M. Bailey ,  Philippe Vernot ,  Sebastien Lefebvre

IPC: B01D15/14 ,  B23P19/00

CPC classification number: B01D15/22 ,  G01N30/6047

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract translation: 在制备色谱柱中用作上壳体的柱塞由一个或多个杆悬挂，所述杆由框架支撑，框架上的联接连接件可以相对于框架固定杆的位置，而位置 的杆由一个悬挂在柱上方的电动驱动系统控制。 驱动系统安装在柱盖或定位在柱盖上方短距离的功能板上。 这些结构允许柱塞被升高和降低，使得柱和其部件可以更换，而不需要起重机或起重机。

公开(公告)号：US07718058B2

公开(公告)日：2010-05-18

申请号：US12107916

申请日：2008-04-23

Applicant: Maurice Agee ,  Sebastien Lefebvre ,  Sebastien Magnaud ,  Philippe Vernot

Inventor： Maurice Agee ,  Sebastien Lefebvre ,  Sebastien Magnaud ,  Philippe Vernot

IPC: B01D15/08

CPC classification number: G01N30/6004 ,  B01D15/20 ,  B01D15/206 ,  B01D15/22 ,  G01N30/56

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.

Abstract translation: 制备色谱柱配备有一个或多个阀，每个阀都可以用于将塔填料注入塔中或从塔中抽出用过的填料，除了清洁与阀本身相关的供给和排出管线之外，全部由 将可动塞移动到阀体内，而不会突出到柱内部。 每个阀门安装在立柱底部的过滤板正上方的柱的侧壁上，并且塞子可以在闭合位置之间移动，其中塞子的端面与柱的内壁齐平，并且打开 插头凹入孔内的位置。 每个阀在其阀体中具有两个附加端口，定位成使得当塞子闭合时，两个端口都对阀孔开放，并且当塞子打开时，至少一个端口对孔开放。 插头在阀孔内的位置决定了阀门的功能。

公开(公告)号：US20090134441A1

公开(公告)日：2009-05-28

申请号：US12365475

申请日：2009-02-04

Applicant: Philippe Candellier ,  Thierry Devoivre ,  Emmanuel Josse ,  Sebastien Lefebvre

Inventor： Philippe Candellier ,  Thierry Devoivre ,  Emmanuel Josse ,  Sebastien Lefebvre

IPC: H01L29/94 ,  H01L21/8242

CPC classification number: H01L27/0207 ,  H01L27/112 ,  H01L27/11206 ,  H01L27/11246

Abstract: A non-volatile memory element includes a transistor for selecting the element and a capacitor for recording a binary value by electrical breakdown of an insulating layer of the capacitor. A structure of the memory element is modified in order to allow a higher degree of integration of the element within an electronic circuit of the MOS type. In addition, the memory element is made more robust with respect to a high electrical voltage (VDD) used for recording the binary value. The transistor includes a drain in the substrate with electric field drift in a longitudinal direction extending towards the capacitor. The electric field drift region for the drain includes a first extension underneath the gate of the transistor opposite the source and a second extension underneath the insulating layer of the capacitor. Doping of the substrate for the electric field drift region is limited to a region substantially corresponding to a distance between the gate and an electrode of the capacitor.

Abstract translation: 非易失性存储元件包括用于选择元件的晶体管和用于通过电容器的绝缘层的电击穿来记录二进制值的电容器。 修改存储元件的结构，以便允许元件在MOS类型的电子电路内更高程度的集成。 此外，存储元件相对于用于记录二进制值的高电压（VDD）更加鲁棒。 该晶体管包括在衬底中的漏极，该漏极沿朝向该电容器延伸的纵向方向具有电场漂移。 用于漏极的电场漂移区域包括与源极相对的晶体管的栅极下面的第一延伸部分和在电容器的绝缘层下方的第二延伸部分。 用于电场漂移区域的衬底的掺杂限于基本上对应于电容器的栅极和电极之间的距离的区域。

公开(公告)号：US20080264837A1

公开(公告)日：2008-10-30

申请号：US12107916

申请日：2008-04-23

Applicant: Maurice Agee ,  Sebastien Lefebvre ,  Sebastien Magnaud ,  Philippe Vernot

Inventor： Maurice Agee ,  Sebastien Lefebvre ,  Sebastien Magnaud ,  Philippe Vernot

IPC: B07C5/34

CPC classification number: G01N30/6004 ,  B01D15/20 ,  B01D15/206 ,  B01D15/22 ,  G01N30/56

Abstract: A preparative chromatography column is equipped with one or more valves that can each be used to both inject a column packing into the column or withdraw used packing from the column, in addition to cleaning the supply and discharge lines associated with the valve itself, all by moving a movable plug within the valve body and all without protruding into the column interior. Each valve is mounted on the lateral wall of the column just above the filter plate at the column floor, and the plug is movable between a closed position in which the end surface of the plug is flush with the inner wall of the column and an open position in which the plug is recessed within the bore. Each valve has two additional ports in its valve body, positioned such that when the plug is closed, both ports are open to the valve bore, and when the plug is open, at least one of the ports is open to the bore. The position of the plug within the valve bore determines the valve function.

Abstract translation: 制备色谱柱配备有一个或多个阀，每个阀都可以用于将塔填料注入塔中或者从塔中抽出用过的填料，除了清洗与阀本身相关联的供给和排出管线之外，全部由 将可动塞移动到阀体内，而不会突出到柱内部。 每个阀门安装在立柱底部的过滤板正上方的柱的侧壁上，并且塞子可以在闭合位置之间移动，其中塞子的端面与柱的内壁齐平，并且打开 插头凹入孔内的位置。 每个阀在其阀体中具有两个附加端口，定位成使得当塞子闭合时，两个端口都对阀孔开放，并且当塞子打开时，至少一个端口对孔开放。 插头在阀孔内的位置决定了阀门的功能。

公开(公告)号：US20080290016A1

公开(公告)日：2008-11-27

申请号：US11955497

申请日：2007-12-13

Applicant: Daniel M. Bailey ,  Philippe Vernot ,  Sebastien Lefebvre

Inventor： Daniel M. Bailey ,  Philippe Vernot ,  Sebastien Lefebvre

IPC: G01N30/02

CPC classification number: B01D15/22 ,  G01N30/6047

Abstract: The plunger used as the upper enclosure in a preparative chromatography column is suspended by one or more rods that are supported by a frame through coupling connections on the frame that can fix the position of the rod(s) relative to the frame, while the position of the rod(s) is controlled by a motorized drive system that is suspended above the column. The drive system is mounted either to the column lid or to a functional plate positioned a short distance above the column lid. These constructions allow the plunger to be raised and lowered so that the column and its parts can be exchanged, all without the need for a hoist or crane.

Abstract translation: 在制备色谱柱中用作上壳体的柱塞由一个或多个杆悬挂，所述杆由框架支撑，框架上的联接连接件可以相对于框架固定杆的位置，而位置 的杆由一个悬挂在柱上方的电动驱动系统控制。 驱动系统安装在柱盖或位于柱盖上方短距离的功能板上。 这些结构允许柱塞被升高和降低，使得柱和其部件可以更换，而不需要起重机或起重机。

公开(公告)号：US20070211520A1

公开(公告)日：2007-09-13

申请号：US11706865

申请日：2007-02-14

Applicant: Laurent Dedieu ,  Sebastien Lefebvre

Inventor： Laurent Dedieu ,  Sebastien Lefebvre

IPC: G11C11/00

CPC classification number: G11C11/412 ,  H03K3/356008 ,  H03K3/356104

Abstract: An embodiment of the invention relates to a device for memorisation of a memory bit, provided with a bistable circuit with complementary first and second read/write terminals, wherein the device comprises an initialization input connected to said bistable circuit, said input being designed to go into a first state controlling a pre-load phase of said bistable circuit and following said preload phase, to go into a second state controlling setting up of said memory bit and its complement at said read/write terminals.

Abstract translation: 本发明的一个实施例涉及一种用于存储存储器位的装置，其具有互补的第一和第二读/写端子的双稳态电路，其中所述器件包括连接到所述双稳态电路的初始化输入，所述输入被设计为去 控制所述双稳态电路的预加载阶段并遵循所述预加载阶段的第一状态进入控制在所述读/写端子处所述存储器位及其补码的设置的第二状态。

公开(公告)号：US20070114596A1

公开(公告)日：2007-05-24

申请号：US11600584

申请日：2006-11-15

Applicant: Philippe Candelier ,  Thierry Devoivre ,  Emmanuel Josse ,  Sebastien Lefebvre

Inventor： Philippe Candelier ,  Thierry Devoivre ,  Emmanuel Josse ,  Sebastien Lefebvre

IPC: H01L29/792

CPC classification number: H01L27/0207 ,  H01L27/112 ,  H01L27/11206 ,  H01L27/11246

Abstract: A non-volatile memory element includes a transistor for selecting the element and a capacitor for recording a binary value by electrical breakdown of an insulating layer (13) of the capacitor. A structure of the memory element is modified in order to allow a higher degree of integration of the element within an electronic circuit of the MOS type. In addition, the memory element is made more robust with respect to a high electrical voltage (VDD) used for recording the binary value. The transistor includes a drain in the substrate with electric field drift in a longitudinal direction extending towards the capacitor. The electric field drift region for the drain includes a first extension underneath the gate of the transistor opposite the source and a second extension underneath the insulating layer of the capacitor. Doping of the substrate for the electric field drift region is limited to a region substantially corresponding to a distance between the gate and an electrode of the capacitor.

Abstract translation: 非易失性存储元件包括用于选择元件的晶体管和用于通过电容器的绝缘层（13）的电击穿记录二进制值的电容器。 修改存储元件的结构，以便允许元件在MOS类型的电子电路内更高程度的集成。 此外，存储元件相对于用于记录二进制值的高电压（VDD）更加鲁棒。 该晶体管包括在衬底中的漏极，该漏极沿朝向该电容器延伸的纵向方向具有电场漂移。 用于漏极的电场漂移区域包括与源极相对的晶体管的栅极下面的第一延伸部分和在电容器的绝缘层下方的第二延伸部分。 用于电场漂移区域的衬底的掺杂限于基本上对应于电容器的栅极和电极之间的距离的区域。