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1.发明申请公开(公告)号：US20160025752A1
公开(公告)日：2016-01-28
申请号：US14747659
申请日：2015-06-23
IPC分类号： G01N33/94
CPC分类号： G01N33/948 , B01L3/5023 , B01L2200/027 , B01L2300/043 , B01L2300/047 , B01L2300/0825 , B01L2400/0406 , B01L2400/0683 , G01N15/0612 , G01N21/8483 , G01N33/94 , G01N33/946 , G01N2015/0065 , G01N2021/8488 , G01N2035/00108 , G08C17/02
摘要： The present disclosure relates to devices and methods for determining a target analyte in a sample (e.g., a bodily fluid sample such as sweat, blood, urine, lavage, plasma, saliva, tears) using an analysis device (e.g., a bodily fluid analysis device). The device may include a lateral flow assay in some embodiments. Certain embodiments involve determining a concentration of a target analyte in a sample by generating a volumetric calculation of the sample and/or by use of a non-target analyte. The devices and methods can be used for obtaining and processing a sample to determine the presence and/or concentration of such analytes. In some cases, the methods and/or devices can be used to determine impairment (e.g., drug impairment) in a subject.
摘要翻译： 本公开涉及使用分析装置（例如，体液分析法）来确定样品中的目标分析物（例如，体液样品，例如汗液，血液，尿液，灌洗液，血浆，唾液，眼泪）的装置和方法 设备）。 在一些实施方案中，该装置可以包括侧流测定。 某些实施方案涉及通过产生样品的体积计算和/或通过使用非目标分析物来确定样品中目标分析物的浓度。 这些装置和方法可用于获得和处理样品以确定这些分析物的存在和/或浓度。 在某些情况下，方法和/或装置可用于确定受试者的损伤（例如药物损伤）。
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公开(公告)号：US20150093329A1
公开(公告)日：2015-04-02
申请号：US14485199
申请日：2014-09-12
发明人： Gary Johnson , Brian W. Lee
IPC分类号： A61K49/00
CPC分类号： A61K49/0056 , A61K49/0008 , A61K49/0043 , A61K49/0052
摘要： The invention provides methods and products, such as kits, useful for determining the apoptotic state of cells in an organism, comprising detecting the presence or abundance of at least one caspase affinity labeling agent in the cells of an animal into which at least one caspase affinity labeling agent has been introduced, wherein the presence or abundance of the caspase affinity labeling agent correlates with the apoptotic state of the cells.
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