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公开(公告)号:US20030009076A1
公开(公告)日:2003-01-09
申请号:US10236680
申请日:2002-09-06
IPC分类号: A61N005/00
CPC分类号: A61F2/82 , A61F2/07 , A61F2/91 , A61F2/92 , A61F2210/0095 , A61F2250/0039 , A61K51/1272 , A61N5/1002 , A61N2005/1004
摘要: A device, method, and kit for conveying a radioactive agent to a site of stenosis. The device includes a body portion to be disposed about the surface of a stent. The device comprises a radioactive agent. The device is capable of expanding, thus following the deployment movement of the stent, and is used to counter restenosis.
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公开(公告)号:US20020183831A1
公开(公告)日:2002-12-05
申请号:US10159969
申请日:2002-05-31
发明人: Giovanni Rolando , Paolo Gaschino
IPC分类号: A61F002/06
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91541 , A61F2002/9155 , A61F2002/91583 , A61F2230/0054 , A61F2250/0036
摘要: This invention is a stent having a substantially tubular body defining a longitudinal axis comprising first and second adjacent annular segments, each segment defining a substantially sinusoidal shape having a plurality of peaks and valleys, the peaks of the first segment extending toward the second segment and being aligned longitudinally with the valleys of the second segment. The stent has a plurality of bridge elements having a U-shaped portion between first and second connector arms, the first connector arm of one bridge element being connected between a first peak and a first valley of the first segment and the second connector arm being connected between a first peak and a first valley of the second segment.
摘要翻译: 本发明是一种支架,其具有限定纵向轴线的基本上管状的主体,该纵向轴线包括第一和第二相邻的环形段,每个段限定具有多个峰和谷的基本正弦形状,第一段的峰向第二段延伸, 与第二段的谷部纵向对齐。 支架具有在第一和第二连接器臂之间具有U形部分的多个桥接元件,一个桥接元件的第一连接臂连接在第一段的第一峰与第一谷之间,第二连接臂连接 在第二段的第一峰和第一谷之间。
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公开(公告)号:US20020117264A1
公开(公告)日:2002-08-29
申请号:US10135639
申请日:2002-04-30
IPC分类号: A61L002/00
CPC分类号: A61L27/00 , A61F2/0077 , A61F2/0095 , A61F2/02 , A61F2/06 , A61F2/2409 , A61L33/0005 , Y10T156/1744
摘要: A prosthesis having an apertured structure is located in a chamber (11) which is taken to sub-atmospheric pressure. Once sub-atmospheric pressure has been reached, a liquid, optionally containing pharmacological agents, is introduced into the chamber. Drawn by the sub-atmospheric pressure, the liquid saturates the apertured structure of the prosthesis. In this way, the invention eliminates the risk of air being trapped in the apertured structure that could give rise to the formation of blood clots after implantation of the prosthesis. The liquid can contain drugs that penetrate the prosthesis, performing their therapeutic action locally and over time after implantation.
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公开(公告)号:US20010049541A1
公开(公告)日:2001-12-06
申请号:US09299862
申请日:1999-04-26
IPC分类号: A61N001/362
CPC分类号: A61N1/3622 , A61N1/3962
摘要: An implantable heart-stimulation apparatus having a plurality of stimulation electrodes which can be applied to the heart muscle in one or more chambers of the heart in order to apply electrical stimulation signals thereto, and stimulation-control means for applying stimulation signals to the electrodes in accordance with a time plan determined individually and separately for each of the plurality of electrodes. The preferred application is for the correction of myocardial electrical conduction defects, for example, in atrial fibrillation and cardiac insufficiency.
摘要翻译: 一种植入式心脏刺激装置,其具有多个刺激电极,其能够施加到心脏的一个或多个腔室中的心脏肌肉以便向其施加电刺激信号,以及刺激控制装置,用于向电极施加刺激信号 根据对于多个电极中的每一个分别确定的时间表。 优选的应用是用于校正心肌电传导缺陷,例如心房颤动和心脏功能不全。
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公开(公告)号:US20040153140A1
公开(公告)日:2004-08-05
申请号:US10626292
申请日:2003-07-24
发明人: Giovanni Rolando , Paolo Gaschino
IPC分类号: A61F002/06
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/9155 , A61F2002/91566
摘要: An angioplasty stent comprises a body comprising a plurality of successive segments connected in pairs by bridge means so that the successive segments can be oriented relative to one another for the purposes of bending of the body in any direction defined by a linear combination of respective orientation axes defined by the bridge connection means. During the radial expansion of the stent, the axial contraction of the segments resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements from the respective concave portions. The wall of the body comprises arms for supporting a lumen as well as regions which are selectively deformable during the expansion of the stent, the arms and the selectively deformable regions having different cross-sections and/or cross-sectional areas. At least one portion of the body may have a substantially reticular structure, the branches of which define geometrical figures identifiable as fractals.
摘要翻译: 血管成形术支架包括主体,其包括通过桥接装置成对连接的多个连续部分,使得连续部分可以相对于彼此定向,用于在由相应定向轴线性组合限定的任何方向上弯曲身体 由桥连接装置限定。 在支架的径向膨胀期间,由相应的凹部的桥接元件的轴向突出来补偿由各个环的打开引起的段的轴向收缩。 主体的壁包括用于支撑内腔的臂以及在支架膨胀期间可选择性地变形的区域,臂和可选择性地变形的区域具有不同的横截面积和/或横截面积。 身体的至少一部分可以具有基本上网状结构,其分支限定可识别为分形的几何图形。
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公开(公告)号:US20020052647A1
公开(公告)日:2002-05-02
申请号:US10001519
申请日:2001-10-30
IPC分类号: A61F002/06
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/9155 , A61F2002/91566
摘要: An angioplasty stent comprises a body comprising a plurality of successive segments connected in pairs by bridge means so that the successive segments can be oriented relative to one another for the purposes of bending of the body in any direction defined by a linear combination of respective orientation axes defined by the bridge connection means. During the radial expansion of the stent, the axial contraction of the segments resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements from the respective concave portions. The wall of the body comprises arms for supporting a lumen as well as regions which are selectively deformable during the expansion of the stent, the arms and the selectively deformable regions having different cross-sections and/or cross-sectional areas. At least one portion of the body may have a substantially reticular structure, the branches of which define geometrical figures identifiable as fractals.
摘要翻译: 血管成形术支架包括主体,其包括通过桥接装置成对连接的多个连续部分,使得连续部分可以相对于彼此定向,用于在由相应定向轴线性组合限定的任何方向上弯曲身体 由桥连接装置限定。 在支架的径向膨胀期间,由相应的凹部的桥接元件的轴向突出来补偿由各个环的打开引起的段的轴向收缩。 主体的壁包括用于支撑内腔的臂以及在支架膨胀期间可选择性地变形的区域,臂和可选择性地变形的区域具有不同的横截面积和/或横截面积。 身体的至少一部分可以具有基本上网状结构,其分支限定可识别为分形的几何图形。
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公开(公告)号:US20040172124A1
公开(公告)日:2004-09-02
申请号:US10790649
申请日:2004-03-01
发明人: Franco Vallana , Giovanni Rolando , Maria Curcio , Paolo Gaschino
IPC分类号: A61F002/06
CPC分类号: A61F2/91 , A61F2/915 , A61F2002/91541 , A61F2002/9155 , A61F2002/91583 , A61F2230/0054 , A61F2250/0068
摘要: A stent for use at an implant site in a vessel having recesses containing one or more active agents. The stent is a tubular body having a plurality of sinusoidal shaped annular elements and connection elements. The recesses are formed so as to leave substantially unaltered the bending moments of these elements. The recesses may be continuous or discontinuous and may be distributed uniformly or nonuniformly.
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公开(公告)号:US20030195613A1
公开(公告)日:2003-10-16
申请号:US10431557
申请日:2003-05-07
发明人: Maria Curcio , Giovanni Rolando , Franco Vallana
IPC分类号: A61F002/06
CPC分类号: A61F2/82 , A61F2/0077 , A61F2/86 , A61F2250/0025 , A61F2250/0068 , A61F2310/00574 , A61F2310/0058 , A61L31/022 , A61L31/084 , A61L31/14 , A61L31/16 , A61L33/025 , A61L2300/416 , A61L2300/42 , A61L2400/18 , Y10T29/49885 , Y10T29/49995
摘要: A stent has surface sculpturing, preferably on its outer surface only, having, for example, microspheres, having the function of increasing the actual geometric surface area of the stent, of creating undercuts and roughness to encourage the application of coatings of active or activatable agents, as well as of improving the attachment of the stent to the blood vessel wall.
摘要翻译: 支架具有表面雕刻,优选仅在其外表面上具有例如具有增加支架的实际几何表面积的功能的微球,产生底切和粗糙度以促进施加活性或可激活剂的涂层 ,以及改善支架到血管壁的附着。
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公开(公告)号:US20020072793A1
公开(公告)日:2002-06-13
申请号:US10002783
申请日:2001-10-30
发明人: Giovanni Rolando , Paolo Gaschino
IPC分类号: A61F002/06
CPC分类号: A61F2/915 , A61F2/91 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/9155 , A61F2002/91566
摘要: An angioplasty stent comprises a body comprising a plurality of successive segments connected in pairs by bridge means so that the successive segments can be oriented relative to one another for the purposes of bending of the body in any direction defined by a linear combination of respective orientation axes defined by the bridge connection means. During the radial expansion of the stent, the axial contraction of the segments resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements from the respective concave portions. The wall of the body comprises arms for supporting a lumen as well as regions which are selectively deformable during the expansion of the stent, the arms and the selectively deformable regions having different cross-sections and/or cross-sectional areas. At least one portion of the body may have a substantially reticular structure, the branches of which define geometrical figures identifiable as fractals.
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公开(公告)号:US20010018600A1
公开(公告)日:2001-08-30
申请号:US09852874
申请日:2001-05-10
IPC分类号: A61N001/362
CPC分类号: A61N1/3622 , A61N1/368
摘要: Electrodes can generate electrical stimulation pulses at least one first intensity level and at least one second intensity level. The first and second intensity levels are above and below a given stimulation threshold, respectively. The synchronous or asynchronous delivery of second-level pulses enables the conduction of the atrioventricular node to be modulated by electrotonic effect, for example, to reduce ventricular frequency in the event of atrial fibrillation.
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