Abstract:
The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
Abstract:
A perfusion device (10) is described, particularly for electro-physiological and/or optical examinations on biological objects (1) which comprises a chamber body (20) in which a perfusion chamber (21, 25) is formed with at least one input opening (22, 23) and at least one discharge (24), and a holding device (30) for holding at least one object (1) to be examined in the perfusion chamber, the holding device (30) comprising a projection that forms a seat (31) on its upper end for the object (1) to be examined and is level-adjustably arranged in the perfusion chamber (21, 25) and, if the holding device (30) protrudes into the perfusion chamber (21, 25), a circumferential perfusion gap (25) being formed laterally and relative to the chamber body (20), which gap is connected to the discharge (24).
Abstract:
In an apparatus used for perfusion-treating objects within a defined treatment area of a liquid bath, the apparatus having a ring having a lower edge which is sealingly placeable on the bottom of the liquid bath and an interior for connection to a liquid conveying device. The ring includes a holding member for receiving an inlet member of the liquid conveying device, or a wall having at least one wall chamber which communicates with the holding member on the ring and with the interior of the ring.
Abstract:
The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
Abstract:
Disclosed is a liquid holder mechanism (10) which is designed to form a liquid environment at a capillary tip (22) of a patch clamp pipette (20) and includes a holding element (11.2) for retaining a liquid drop (1) and at least one rod (12.2, 12.3) for positioning the holding element (11.2) on the capillary tip (22). The at least one rod (12.2, 12.3) is designed such that the holding element (11.2) can be separated from the capillary (21) in a state in which the liquid holder mechanism (10) is connected to the patch clamp pipette (20). Also disclosed are a measuring instrument that is equipped with said liquid holder mechanism (10) as well as a method for electrophysically analyzing a biological cell with the help of the liquid holder mechanism (10).
Abstract:
The present invention is directed to compounds, intermediates and methods for making valerenic acid and its derivatives as well as the use of such compounds as GABAA receptor ligands.
Abstract:
An ultrasonic probe with an ultrasonic head (K), which is arranged on or in a shaft (S) and is moveable with or in this shaft, and a positioning apparatus (P) for at least one examination or operating device is described, which is connected with the shaft. Also, medical operating apparatuses with examination probes and uses of the ultrasonic probe and the medical implements are described.