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公开(公告)号：US20070140987A1
公开(公告)日：2007-06-21
申请号：US11701848
申请日：2007-02-01
IPC分类号： A61K9/68 , A61K31/4745 , A61K8/00 , A23K1/165 , A61K31/44
CPC分类号： A61Q11/00 , A61K8/347 , A61K8/416 , A61K8/43 , A61K8/49 , A61K8/4926 , A61K9/006 , A61K31/05 , A61K31/14 , A61K31/155 , A61K31/44 , A61K31/4745 , A61K33/24 , A61K33/30 , A61K33/34 , A61K45/06
摘要： The present invention relates to promoting whole body health in humans and animals by using topical oral compositions comprising a safe and effective amount of an antimicrobial agent in admixture with a pharmaceutically acceptable carrier, said compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and in inhibiting the spread into the bloodstream of pathogenic oral bacteria, associated bacterial toxins and endotoxins, and resultant inflammatory cytokines and mediators. The present invention also encompasses methods of use of these compositions by topically applying to the oral cavity, a safe and effective amount of an antimicrobial agent to promote and/or enhance whole body health in humans and other animals.
摘要翻译： 本发明涉及通过使用包含安全有效量的抗微生物剂与药学上可接受的载体混合的局部口服组合物来促进人和动物的全身健康，所述组合物有效地控制细菌介导的疾病和病症 口腔和抑制扩散到病原性口腔细菌，相关细菌毒素和内毒素的血液中，以及产生的炎性细胞因子和介质。 本发明还包括通过局部施用于口腔使用这些组合物的方法，一种安全有效量的抗微生物剂以促进和/或增强人和其他动物的全身健康。
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公开(公告)号：US20060193790A1
公开(公告)日：2006-08-31
申请号：US11409850
申请日：2006-04-24
IPC分类号： A61K36/18 , A61K9/68 , A61K31/675 , A61K38/43 , A61K31/60 , A61K31/525 , A61K31/353 , A61K31/198 , A61K31/192
CPC分类号： A61Q11/00 , A61K8/4946 , A61K8/4973 , A61K31/00 , A61K31/407 , A61K31/4164 , A61K31/426 , A61K31/662 , A61K45/06
摘要： The present invention relates to promoting whole body health in humans and animals by using topical oral compositions comprising a safe and effective amount of a host-response modulating agent in admixture with a pharmaceutically acceptable carrier, said compositions being effective in mediating host reaction to the presence of periodontal pathogens in the oral cavity as well as the toxins and endotoxins released by these pathogens and the inflammatory cytokines and mediators prompted by these oral pathogens.
摘要翻译： 本发明涉及通过使用包含安全有效量的宿主 - 反应调节剂与药学上可接受的载体混合的局部口服组合物来促进人和动物的全身健康，所述组合物有效地介导宿主对存在的反应 的牙周病原体以及由这些病原体释放的毒素和内毒素以及由这些口腔病原体引起的炎性细胞因子和介质。
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公开(公告)号：US20050163727A1
公开(公告)日：2005-07-28
申请号：US10854065
申请日：2004-05-25
IPC分类号： A61K8/00 , A01N33/12 , A61K8/20 , A61K8/33 , A61K8/34 , A61K8/40 , A61K8/41 , A61K8/43 , A61K8/49 , A61K8/64 , A61K9/68 , A61K31/05 , A61K31/085 , A61K31/14 , A61K31/155 , A61K31/44 , A61K31/4425 , A61K33/00 , A61K33/24 , A61K33/30 , A61K33/34 , A61K45/00 , A61K45/06 , A61P1/02 , A61P3/10 , A61P9/00 , A61P9/10 , A61P11/00 , A61P15/00 , A61P31/02 , A61Q11/00 , A61K7/16 , A61K7/20
CPC分类号： A61Q11/00 , A61K8/347 , A61K8/416 , A61K8/43 , A61K8/49 , A61K8/4926 , A61K9/006 , A61K31/05 , A61K31/14 , A61K31/155 , A61K31/44 , A61K31/4745 , A61K33/24 , A61K33/30 , A61K33/34 , A61K45/06
摘要： The present invention relates to promoting whole body health in humans and animals by using topical oral compositions comprising a safe and effective amount of an antimicrobial agent in admixture with a pharmaceutically acceptable carrier, said compositions being effective in controlling bacterial-mediated diseases and conditions present in the oral cavity and in inhibiting the spread into the bloodstream of pathogenic oral bacteria, associated bacterial toxins and endotoxins, and resultant inflammatory cytokines and mediators. The present invention also encompasses methods of use of these compositions by topically applying to the oral cavity, a safe and effective amount of an antimicrobial agent to promote and/or enhance whole body health in humans and other animals.
摘要翻译： 本发明涉及通过使用包含安全有效量的抗微生物剂与药学上可接受的载体混合的局部口服组合物来促进人和动物的全身健康，所述组合物有效地控制细菌介导的疾病和病症 口腔和抑制扩散到病原性口腔细菌，相关细菌毒素和内毒素的血液中，以及产生的炎性细胞因子和介质。 本发明还包括通过局部施用于口腔使用这些组合物的方法，一种安全有效量的抗微生物剂以促进和/或增强人和其他动物的全身健康。
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